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Cancer Chemotherapy and Pharmacology

Ausgabe 1/2021

Inhalt (18 Artikel)

Review Article

Use of cucurbitacins for lung cancer research and therapy

Min Liu, Qijia Yan, Bi Peng, Yuan Cai, Shuangshuang Zeng, Zhijie Xu, Yuanliang Yan, Zhicheng Gong

Review Article

Cardiovascular toxicity of breast cancer treatment: an update

Christos Papageorgiou, Angeliki Andrikopoulou, Meletios-Athanasios Dimopoulos, Flora Zagouri

Open Access Original Article

Niraparib with androgen receptor-axis-targeted therapy in patients with metastatic castration-resistant prostate cancer: safety and pharmacokinetic results from a phase 1b study (BEDIVERE)

Fred Saad, Kim N. Chi, Neal D. Shore, Julie N. Graff, Edwin M. Posadas, Jean-Baptiste Lattouf, Byron M. Espina, Eugene Zhu, Alex Yu, Anasuya Hazra, Marc De Meulder, Rao N. V. S. Mamidi, Branislav Bradic, Peter Francis, Vinny Hayreh, Arash Rezazadeh Kalebasty

Original Article

Pharmacogenomics and functional imaging to predict irinotecan pharmacokinetics and pharmacodynamics: the predict IR study

Michael Michael, Winston Liauw, Sue-Anne McLachlan, Emma Link, Annetta Matera, Michael Thompson, Michael Jefford, Rod J. Hicks, Carleen Cullinane, Athena Hatzimihalis, Ian G. Campbell, Simone Rowley, Phillip J. Beale, Christos S. Karapetis, Timothy Price, Mathew E. Burge

Original Article

Dynamics of leucocyte DNA thioguanine nucleotide levels during maintenance therapy of childhood acute lymphoblastic leukemia

Rikke Hebo Larsen, Lisa Lyngsie Hjalgrim, Matilda Degn, Jacob Nersting, Bodil Als-Nielsen, Kathrine Grell, Kjeld Schmiegelow

Original Article

Oral recombinant methioninase combined with paclitaxel arrests recalcitrant ovarian clear cell carcinoma growth in a patient-derived orthotopic xenograft (PDOX) nude-mouse model

Norihiko Sugisawa, Takashi Higuchi, Qinghong Han, Chihiro Hozumi, Jun Yamamoto, Yoshihiko Tashiro, Hiroto Nishino, Kei Kawaguchi, Michael Bouvet, Takuya Murata, Michiaki Unno, Robert M. Hoffman

Original Article

Selinexor population pharmacokinetic and exposure–response analyses to support dose optimization in patients with diffuse large B-cell lymphoma

Hongmei Xu, Hanbin Li, Russ Wada, Justin C. Bader, Shijie Tang, Jatin Shah, Sharon Shacham

Open Access Original Article

The pharmacokinetics of pamiparib in the presence of a strong CYP3A inhibitor (itraconazole) and strong CYP3A inducer (rifampin) in patients with solid tumors: an open-label, parallel-group phase 1 study

Song Mu, Chester Lin, Anna Skrzypczyk-Ostaszewicz, Iurie Bulat, Marina Maglakelidze, Viera Skarbova, Claudia Andreu-Vieyra, Srikumar Sahasranaman

Original Article

Changes in expression of lysosomal membrane proteins in leucocytes of cancer patients treated with tyrosine kinase inhibitors

N. Pastvova, J. Havlasek, P. Dolezel, K. Kikalova, H. Studentova, A. Zemankova, B. Melichar, P. Mlejnek

Original Article

Phase I study of tamibarotene monotherapy in pediatric and young adult patients with recurrent/refractory solid tumors

Chika Nitani, Junichi Hara, Hiroshi Kawamoto, Tomoaki Taguchi, Toshimi Kimura, Kenichi Yoshimura, Akinobu Hamada, Shigehisa Kitano, Naoko Hattori, Toshikazu Ushijima, Hiromi Ono, Masako Nakamoto, Tsukiko Higuchi, Akihiro Sato

Original Article

Impact of adverse events of adjuvant and neoadjuvant chemotherapies on outcomes of patients with pancreatic ductal adenocarcinoma

Shozo Mori, Taku Aoki, Yuhki Sakuraoka, Takayuki Shimizu, Takamune Yamaguchi, Kyung-Hwa Park, Takatsugu Matsumoto, Takayuki Shiraki, Yukihiro Iso, Keiichi Kubota

Original Article

Pharmacokinetics, safety, activity, and biomarker analysis of palbociclib plus letrozole as first-line treatment for ER+/HER2– advanced breast cancer in Chinese women

Binghe Xu, Huiping Li, Qingyuan Zhang, Wan Sun, Yanke Yu, Wei Li, Shusen Wang, Ning Liao, Peng Shen, Yuan Liu, Yaling Huang, Carlos Linn, Huadong Zhao, John Jiang, Diane Wang

Original Article

Sorafenib combined with dasatinib therapy inhibits cell viability, migration, and angiogenesis synergistically in hepatocellular carcinoma

Chiung-Chi Cheng, Wei-Ting Chao, Jing-Hao Shih, Yih-Shyong Lai, Yung-Hsiang Hsu, Yi-Hsiang Liu

Open Access Short Communication

Deep and ongoing response of castrate-resistant prostate cancer on very low-dose enzalutamide in an elderly chemotherapy–naïve patient: a case report

Emmy Boerrigter, Thomas Havenith, Nielka P. van Erp, John-John B. Schnog

Correction

Correction to: Combination efficacy of pertuzumab and trastuzumab for trastuzumab emtansine-resistant cells exhibiting attenuated lysosomal trafficking or efflux pumps upregulation

Yoriko Yamashita‑Kashima, Sei Shu, Masahiro Osada, Takaaki Fujimura, Shigeki Yoshiura, Naoki Harada, Yasushi Yoshimura

Correction

Correction to: Formulae recently proposed to estimate renal glomerular filtration rate improve the prediction of carboplatin clearance

Melanie White-Koning, Marie Noëlle Paludetto, Félicien Le Louedec, Laurence Gladieff, Christine Chevreau, Etienne Chatelut, Florent Puisset

Update Onkologie

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