Ausgabe 3/2010
Inhalt (24 Artikel)
Paclitaxel combined with ifosfamide in anthracycline- and docetaxel-pretreated metastatic breast cancer: activity independence of prior docetaxel resistance
Yong Wha Moon, Joo Hyuk Sohn, Hye Jin Choi, Hyun Chang, Byeong-Woo Park, Seung Il Kim, Seho Park, Ja Seung Koo, Yong Tai Kim, Jae Kyung Roh, Hyun Cheol Chung, Joo-Hang Kim
GCS induces multidrug resistance by regulating apoptosis-related genes in K562/AO2 cell line
Yan Liu, Ke-Ming Xie, Guo-Qing Yang, Xiao-Ming Bai, Yuan-Ping Shi, Hui-Jun Mu, Wei-Zhen Qiao, Bin Zhang, Ping Xie
A phase I dose escalation and pharmacokinetic study of vatalanib (PTK787/ZK 222584) in combination with paclitaxel in patients with advanced solid tumors
E. Gabriela Chiorean, Srikar Malireddy, Anne E. Younger, David R. Jones, Mary-Jane Waddell, Melissa I. Sloop, Menggang Yu, Stephen D. Hall, Bryan Schneider, Christopher J. Sweeney
Phase II study of carboplatin combined with weekly docetaxel in patients with advanced non-small cell lung cancer
Lian Jiang, Dao-yuan Wang, Zhi-hua Zhu, Liang-fa Tang, Xin-heng Hou, Hong-da Zhao, Zheng Xie, Dan-feng Wang
Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines
Ying Wang, Arun K. Rishi, Vineshkumar T. Puliyappadamba, Sunita Sharma, Huanjie Yang, Adi Tarca, Q. Ping Dou, Fulvio Lonardo, John C. Ruckdeschel, Harvey I. Pass, Anil Wali
Putative chemopreventive molecules can increase Nrf2-regulated cell defense in some human cancer cell lines, resulting in resistance to common cytotoxic therapies
Liangao Hu, Weimin Miao, Martin Loignon, Mustapha Kandouz, Gerald Batist
Differential apoptotic response of human cancer cells to organoselenium compounds
Maiko Suzuki, Manabu Endo, Fumiaki Shinohara, Seishi Echigo, Hidemi Rikiishi
DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma
Rikke L. Hedeland, Kristian Hvidt, Jacob Nersting, Susanne Rosthøj, Kim Dalhoff, Birgitte Lausen, Kjeld Schmiegelow
The combination of ERCC1 and XRCC1 gene polymorphisms better predicts clinical outcome to oxaliplatin-based chemotherapy in metastatic colorectal cancer
Jun Liang, Tao Jiang, Ru-yong Yao, Zi-min Liu, Hong-ying Lv, Wei-wei Qi
Influence of DNA repair RAD51 gene variants in overall survival of non-small cell lung cancer patients treated with first line chemotherapy
Augusto Nogueira, Raquel Catarino, Ana Coelho, António Araújo, Mónica Gomes, Rui Medeiros
Patterns of relapse and metastatic spread in HER2-overexpressing breast cancer according to estrogen receptor status
Yeon Hee Park, Soohyeon Lee, Eun Yoon Cho, Yoon La Choi, Jeong Eon Lee, Seok Jin Nam, Jung-Hyun Yang, Jin Seok Ahn, Young-Hyuck Im
Toxicity against gastric cancer cells by combined treatment with 5-fluorouracil and mitomycin c: implication in oxidative stress
Toshiyuki Matsunaga, Yoshitaka Tsuji, Kairyu Kaai, Saki Kohno, Renzo Hirayama, David H. Alpers, Tsugikazu Komoda, Akira Hara
A phase II study of induction chemotherapy with gemcitabine plus S-1 followed by chemoradiotherapy for locally advanced pancreatic cancer
Kohei Nakachi, Junji Furuse, Taira Kinoshita, Mitsuhiko Kawashima, Hiroshi Ishii, Masafumi Ikeda, Shuichi Mitsunaga, Satoshi Shimizu
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells
Andrew J. Massey, Douglas S. Williamson, Helen Browne, James B. Murray, Pawel Dokurno, Terry Shaw, Alba T. Macias, Zoe Daniels, Stephanie Geoffroy, Melanie Dopson, Paul Lavan, Natalia Matassova, Geraint L. Francis, Christopher J. Graham, Rachel Parsons, Yikang Wang, Antony Padfield, Mike Comer, Martin J. Drysdale, Mike Wood
Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines
Sara Nannizzi, Gareth J. Veal, Elisa Giovannetti, Valentina Mey, Simona Ricciardi, Christopher J. Ottley, Mario Del Tacca, Romano Danesi
Phase II study of sequential cisplatin plus 5-fluorouracil/leucovorin (5-FU/LV) followed by irinotecan plus 5-FU/LV followed by docetaxel plus 5-FU/LV in patients with metastatic gastric or gastro-oesophageal junction adenocarcinoma
Fotios Loupakis, Gianluca Masi, Lorenzo Fornaro, Enrico Vasile, Giacomo Allegrini, Eloise Fontana, Cristina Granetto, Lisa Salvatore, Lucia Mentuccia, Michele Andreuccetti, Enrico Cortesi, Marco Merlano, Stefano Cascinu, Alfredo Falcone
Anemia response and safety to epoetin-beta treatment in patients with neoadjuvant therapy prior to primary digestive tract tumor surgery
Antonio Gómez, Mercedes Salgado, Manuel Valladares-Ayerbes, Mónica Jorge, Ana Carballo, Sonia Candamio, Enrique Castro, Rafael López
Synergistic interactions between aminoflavone, paclitaxel and camptothecin in human breast cancer cells
Kathryn E. Reinicke, Mary J. Kuffel, Matthew P. Goetz, Matthew M. Ames
Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells
Seema-Maria Nathwani, Stephen Butler, Darren Fayne, Naomi N. McGovern, Balazs Sarkadi, Mary J. Meegan, David G. Lloyd, Giuseppe Campiani, Mark Lawler, D. Clive Williams, Daniela M. Zisterer
Ixabepilone plus capecitabine for Chinese patients with metastatic breast cancer progressing after anthracycline and taxane treatment
Jiayu Wang, Ying Fan, Binghe Xu
Acquired KRAS mutations during progression of colorectal cancer metastases: possible implications for therapy and prognosis
Mohamed Bouchahda, Abdoulaye Karaboué, Raphaël Saffroy, Pasquale Innominato, Lee Gorden, Catherine Guettier, René Adam, Francis Lévi
The histone deacetylase inhibitor vorinostat induces calreticulin exposure in childhood brain tumour cells in vitro
Jürgen Sonnemann, Stephanie Greßmann, Sabine Becker, Susan Wittig, Mareike Schmudde, James F. Beck
MDR1 C2005T polymorphism changes substrate specificity
Lijuan Liu, Lan Fan, Xiangdong Peng, Dongli Hu, Honghao Zhou