Ausgabe 3/2014
Inhalt (26 Artikel)
Clinical challenges in targeting anaplastic lymphoma kinase in advanced non-small cell lung cancer
Namrata Vijayvergia, Ranee Mehra
Phase II trial of gemcitabine plus UFT as salvage treatment in oxaliplatin, irinotecan and fluoropyrimidine-refractory metastatic colorectal cancer
Keun-Wook Lee, Yu Jung Kim, Kyung-Hun Lee, Sae-Won Han, Tae-Yong Kim, Do-Youn Oh, Seock-Ah Im, Tae-You Kim, Yung-Jue Bang, In Sil Choi, Jee Hyun Kim
Correlation of toxicity and efficacy with pharmacokinetics (PK) of pegylated liposomal doxorubicin (PLD) (Caelyx®)
Marye J. Boers-Sonderen, Carla M. L. van Herpen, Winette T. A. van der Graaf, Ingrid M. E. Desar, Mirjam G. W. Arens- van der Logt, Yvo M. de Beer, Petronella B. Ottevanger, Nielka P. van Erp
Phase Ib study of dovitinib in combination with gemcitabine plus cisplatin or gemcitabine plus carboplatin in patients with advanced solid tumors
Matthew D. Galsky, Marshall Posner, Randall F. Holcombe, Karen M. Lee, Krzysztof Misiukiewicz, Che-Kai Tsao, James Godbold, Rothschild Soto, Kiev Gimpel-Tetra, Nancy Lowe, William K. Oh
Studies on assessment methods of malignant ascites residue and changes of verapamil concentration in intraperitoneal perfusion chemotherapy
Chengtao Wen, Qiaohong Duan, Tengyue Zhang, Yabei Liu, Yang Wu, Kelong Ma, Pingsheng Fan, Weidong Jia
A multicenter phase II study of G17DT immunogen plus irinotecan in pretreated metastatic colorectal cancer progressing on irinotecan
Caio Max Rocha-Lima, Eriberto de Queiroz Marques Junior, Soley Bayraktar, Paul Broome, Charles Weissman, Marek Nowacki, Martin Leslie, Shabbir Susnerwala
KPT-330 inhibitor of XPO1-mediated nuclear export has anti-proliferative activity in hepatocellular carcinoma
Yun Zheng, Sigal Gery, Haibo Sun, Sharon Shacham, Michael Kauffman, H. Phillip Koeffler
A phase II study of amrubicin and carboplatin for previously untreated patients with extensive-disease small cell lung cancer
Takaya Ikeda, Minoru Fukuda, Yoichi Nakamura, Akitoshi Kinoshita, Hiroaki Senju, Hirofumi Nakano, Takeshi Kitazaki, Daiki Ogawara, Hirokazu Taniguchi, Kohei Motoshima, Hiroyuki Yamaguchi, Katsumi Nakatomi, Midori Shimada, Seiji Nagashima, Kazuhiro Tsukamoto, Shigeru Kohno
Biweekly S-1 plus paclitaxel (SPA) as second-line chemotherapy after failure from fluoropyrimidine and platinum in advanced gastric cancer: a phase II study
Yulong Zheng, Weijia Fang, Chenyu Mao, Joing Qian, Peng Zhao, Xiaochen Zhang, Haiping Jiang, Yi Zheng, Nong Xu
Inhibition of Hec1 as a novel approach for treatment of primary liver cancer
Lynn YL Huang, Chia-chi Chang, Ying-Shuan Lee, Jiann-Jyh Huang, Shih-Hsien Chuang, Jia-Ming Chang, Kuo-Jang Kao, Gillian MG Lau, Pei-Yi Tsai, Chia-wei Liu, Her-Sheng Lin, Robert G. Gish, Johnson YN Lau
Clinicopathological features of early failure of neoadjuvant chemotherapy in locally advanced breast cancer
Moon Ki Choi, Yeon Hee Park, Won Ho Kil, Jeong Eon Lee, Seok Jin Nam, Jin Seok Ahn, Young-Hyuck Im
RETRACTED ARTICLE: Aplysin enhances temozolomide sensitivity in glioma cells by increasing miR-181 level
Anjing Gong, Na Ge, Weicheng Yao, Luxiang Lu, Hui Liang
No pharmacokinetic alteration of docetaxel following coadministration of aprepitant 3 h before docetaxel infusion
Toshikado Kaneta, Ken-ichi Fujita, Yuko Akiyama, Kaori Kawara, Yu Sunakawa, Asuka Kawachi, Ken Shimada, Yasutsuna Sasaki
Validation of a novel procedure for quantification of the formation of phosphoramide mustard by individuals treated with cyclophosphamide
Hans von Stedingk, Hanjing Xie, Thomas Hatschek, Theodoros Foukakis, Andreas Rydén, Jonas Bergh, Per Rydberg
Modulatory effects of meloxicam on cardiotoxicity and antitumor activity of doxorubicin in mice
Memy H. Hassan, Hesham A. El-Beshbishy, Hamdy Aly, Sabry M. Attia, Saleh A. Bahashwan, Mohamed M. Ghobara
Population pharmacokinetics of peritoneal, plasma ultrafiltrated and protein-bound oxaliplatin concentrations in patients with disseminated peritoneal cancer after intraperitoneal hyperthermic chemoperfusion of oxaliplatin following cytoreductive surgery: correlation between oxaliplatin exposure and thrombocytopenia
Quentin Chalret du Rieu, Mélanie White-Koning, Laetitia Picaud, Isabelle Lochon, Sabrina Marsili, Laurence Gladieff, Etienne Chatelut, Gwenaël Ferron
A phase 1 study to evaluate effect of food on veliparib pharmacokinetics and relative bioavailability in subjects with solid tumors
Nael M. Mostafa, Yi-Lin Chiu, Lee S. Rosen, Alberto Bessudo, Xenia Kovacs, Vincent L. Giranda
Mechanism-based pharmacokinetic/pharmacodynamic meta-analysis of navitoclax (ABT-263) induced thrombocytopenia
Aksana Kaefer, Jianning Yang, Peter Noertersheuser, Sven Mensing, Rod Humerickhouse, Walid Awni, Hao Xiong
Tamoxifen plus tegafur-uracil (TUFT) versus tamoxifen plus Adriamycin (doxorubicin) and cyclophosphamide (ACT) as adjuvant therapy to treat node-positive premenopausal breast cancer (PreMBC): results of Japan Clinical Oncology Group Study 9404
Tadahiko Shien, Hiroji Iwata, Takashi Fukutomi, Kenichi Inoue, Kenjiro Aogi, Takayuki Kinoshita, Jiro Ando, Seiki Takashima, Kenichi Nakamura, Taro Shibata, Haruhiko Fukuda
Liposomal anthracycline chemotherapy and the risk of second malignancies in patients with Kaposi’s sarcoma (KS)
M. Bendle, J. Pealing, P. Papanastasopoulos, M. Bower
Determining the mechanisms of lapatinib-induced diarrhoea using a rat model
Joanne M. Bowen, Bronwen J. Mayo, Erin Plews, Emma Bateman, Anthony Wignall, Andrea M. Stringer, Frances M. Boyle, Dorothy M. K. Keefe
Phase I dose-escalation study of the HSP90 inhibitor AUY922 in Japanese patients with advanced solid tumors
Toshihiko Doi, Yusuke Onozawa, Nozomu Fuse, Takayuki Yoshino, Kentaro Yamazaki, Junichiro Watanabe, Mikhail Akimov, Matthew Robson, Narikazu Boku, Atsushi Ohtsu
Phase I clinical trial of pegylated liposomal mitoxantrone plm60-s: pharmacokinetics, toxicity and preliminary efficacy
Jianliang Yang, Yuankai Shi, Chunlei Li, Lin Gui, Xi Zhao, Peng Liu, Xiaohong Han, Yuanyuan Song, Ning Li, Ping Du, Shuxiang Zhang
Metronomics chemotherapy: time for computational decision support
Dominique Barbolosi, Joseph Ciccolini, Christophe Meille, Xavier Elharrar, Christian Faivre, Bruno Lacarelle, Nicolas André, Fabrice Barlesi
Bortezomib-associated peripheral neuropathy requiring medical treatment is decreased by administering the medication by subcutaneous injection in Korean multiple myeloma patients
Youngil Koh, So Young Lee, Inho Kim, Ji-Hyun Kwon, Sung-Soo Yoon, Seonyang Park, Mi Hye Chung, Sung Yun Suh, Kwi Suk Kim, Hyang Sook Kim
Erratum to: No clinically significant drug interactions between lenalidomide and P-glycoprotein substrates and inhibitors: results from controlled phase I studies in healthy volunteers
Nianhang Chen, Daniel Weiss, Josephine Reyes, Liangang Liu, Claudia Kasserra, Xiaomin Wang, Simon Zhou, Gondi Kumar, Lilia Weiss, Maria Palmisano