Ausgabe 3/2017
Inhalt (24 Artikel)
A review of oral cannabinoids and medical marijuana for the treatment of chemotherapy-induced nausea and vomiting: a focus on pharmacokinetic variability and pharmacodynamics
Melissa E. Badowski
sIL-24 peptide, a human interleukin-24 isoform, induces mitochondrial-mediated apoptosis in human cancer cells
Samira Valiyari, Mona Salami, Reza Mahdian, Mohammad Ali Shokrgozar, Mana Oloomi, Azadeh Mohammadi Farsani, Saeid Bouzari
Carboplatin plus weekly nanoparticle albumin-bound paclitaxel in elderly patients with previously untreated advanced squamous non-small-cell lung cancer selected based on Mini Nutritional Assessment short-form scores: a multicenter phase 2 study
Takayuki Shiroyama, Motohiro Tamiya, Seigo Minami, So Takata, Kentaro Masuhiro, Yu Futami-Nishijima, Takeshi Uenami, Masahide Mori, Taro Koba, Takanori Matsuki, Takayuki Takimoto, Hidekazu Suzuki, Norio Okamoto, Kiyoshi Komuta, Tomonori Hirashima, Atsushi Kumanogoh, Takashi Kijima
Short infusion of paclitaxel imbalances plasmatic lipid metabolism and correlates with cardiac markers of acute damage in patients with breast cancer
C. Panis, R. Binato, S. Correa, V. J. Victorino, V. Dias-Alves, A. C. S. A. Herrera, R. Cecchini, A. N. C. Simão, D. S. Barbosa, L. Pizzatti, E. Abdelhay
Impact of an alternative steroid on the relative bioavailability and bioequivalence of a novel versus the originator formulation of abiraterone acetate
Azra Hussaini, Anthony J. Olszanski, Cy A. Stein, Bill Bosch, Paul Nemeth
Risk of venous and arterial thromboembolic events associated with VEGFR-TKIs: a meta-analysis
Bo Liu, Fengxia Ding, Deying Zhang, Guang-hui Wei
A phase II trial of erlotinib monotherapy in advanced pancreatic cancer as a first- or second-line agent
Christos Fountzilas, Ravi Chhatrala, Nikhil Khushalani, Wei Tan, Charles LeVea, Alan Hutson, Chris Tucker, Wen Wee Ma, Graham Warren, Patrick Boland, Renuka Iyer
Sunitinib is effective and tolerable in Chinese patients with advanced pancreatic neuroendocrine tumors: a multicenter retrospective study in China
Yuhong Wang, Kaizhou Jin, Huangying Tan, Pan Zhang, Qiuchen Yang, Wei Wang, Jie Li, Chenghao Shao, Ling Xue, Shiting Feng, Minhu Chen, Xianjun Yu, Jie Chen
Doxycycline and its quaternary ammonium derivative for adjuvant therapies of chondrosarcoma
Imen Miladi, Magali Vivier, Marie-Mélanie Dauplat, Morgane Chatard, Sophie Besse, Aurélien Vidal, Karine Chassain, Betty Jean, Christiane Forestier, Jean-Michel Chezal, Francoise Rédini, Francoise Degoul, Elisabeth Miot-Noirault
Clarithromycin co-administration does not increase irinotecan (CPT-11) toxicity in colorectal cancer patients
Katsuya Makihara, Sayaka Nakamura, Kazuyo Miyagi, Hiroyuki Ueno, Izumi Nakata
Pharmacokinetics of intravenous pan-class I phosphatidylinositol 3-kinase (PI3K) inhibitor [14C]copanlisib (BAY 80-6946) in a mass balance study in healthy male volunteers
Michael Gerisch, Thomas Schwarz, Dieter Lang, Gabriele Rohde, Stefanie Reif, Isabelle Genvresse, Susanne Reschke, Dorina van der Mey, Camille Granvil
Case series on the association between blood levels and side effects of afatinib maleate
Junya Sato, Naoto Morikawa, Ryosuke Chiba, Satoru Nihei, Satoshi Moriguchi, Heisuke Saito, Kohei Yamauchi, Kenzo Kudo
Psoas muscle volume as a predictor of peripheral neurotoxicity induced by primary chemotherapy in ovarian cancers
Tomoyuki Yoshikawa, Masashi Takano, Morikazu Miyamoto, Isao Yajima, Yukihiro Shimizu, Yusuke Aizawa, Yuki Suguchi, Miki Moriiwa, Tadashi Aoyama, Hiroaki Soyama, Tomoko Goto, Junko Hirata, Ayako Suzuki, Hidenori Sasa, Isao Nagaoka, Hitoshi Tsuda, Kenichi Furuya
A phase I study to investigate the metabolism, excretion, and pharmacokinetics of [14C]fruquintinib, a novel oral selective VEGFR inhibitor, in healthy Chinese male volunteers
Sufeng Zhou, Feng Shao, Zhaoqiang Xu, Lu Wang, Ke Jin, Lijun Xie, Juan Chen, Yun Liu, Hongwen Zhang, Ning Ou
Efficacy and safety of taxane monotherapy in advanced gastric cancer refractory to triplet chemotherapy with docetaxel, cisplatin, and S-1: a multicenter retrospective study
Sakura Iizumi, Atsuo Takashima, Yukiya Narita, Masahiro Tajika, Kei Muro, Sadayuki Kawai, Hirofumi Yasui, Tomohiro Matsushima, Daisuke Takahari, Kengo Nagashima, Narikazu Boku
Clinical predictors of survival in patients with castration-resistant prostate cancer receiving sipuleucel-T cellular immunotherapy
Mehmet Asim Bilen, Kenneth R. Hess, Sumit K. Subudhi, Ana Aparicio, Jeri Kim, Amado J. Zurita-Saavedra, John C. Araujo, Paul G. Corn, Jessica Stover, Sue-Hwa Lin, Christopher J. Logothetis, Shi-Ming Tu
Comparison of RECIST to immune-related response criteria in patients with non-small cell lung cancer treated with immune-checkpoint inhibitors
Hee Kyung Kim, Mi Hwa Heo, Han Sang Lee, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Keunchil Park, Myung-Ju Ahn
Exposure–response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial
Allen Lee Cohn, Takayuki Yoshino, Volker Heinemann, Radka Obermannova, György Bodoky, Jana Prausová, Rocio Garcia-Carbonero, Tudor Ciuleanu, Pilar Garcia-Alfonso, David C. Portnoy, Eric Van Cutsem, Kentaro Yamazaki, Philip R. Clingan, Jonathon Polikoff, Sara Lonardi, Lisa M. O’Brien, Ling Gao, Ling Yang, David Ferry, Federico Nasroulah, Josep Tabernero
Survival data for postoperative adjuvant chemotherapy comprising cisplatin plus vinorelbine after complete resection of non-small cell lung cancer
Hirotsugu Kenmotsu, Yasuhisa Ohde, Kazushige Wakuda, Kazuhisa Nakashima, Shota Omori, Akira Ono, Tateaki Naito, Haruyasu Murakami, Hideaki Kojima, Shoji Takahashi, Mitsuhiro Isaka, Masahiro Endo, Toshiaki Takahashi
A retrospective study of amrubicin monotherapy for the treatment of relapsed small cell lung cancer in elderly patients
Hisao Imai, Tomohide Sugiyama, Tomohiro Tamura, Hiroyuki Minemura, Kyoichi Kaira, Kenya Kanazawa, Hiroshi Yokouchi, Takashi Kasai, Takayuki Kaburagi, Koichi Minato
Concurrent paclitaxel, capecitabine, mitomycin C and pelvic radiation therapy for patients with squamous cell anal carcinoma
Sergey S. Gordeyev, Arsen O. Rasulov, Vera A. Gorbounova, Sergey I. Tkachev, Valeriya V. Glebovskaya, Mikhail Yu. Fedyanin, Nataliya S. Besova, Yulia E. Surayeva
Phase I study of veliparib in combination with gemcitabine
Ronald Stoller, John C. Schmitz, Fei Ding, Shannon Puhalla, Chandra P. Belani, Leonard Appleman, Yan Lin, Yixing Jiang, Salah Almokadem, Daniel Petro, Julianne Holleran, Brian F. Kiesel, R. Ken Czambel, Benedito A. Carneiro, Emmanuel Kontopodis, Pamela A. Hershberger, Madani Rachid, Alice Chen, Edward Chu, Jan H. Beumer
A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript
Patrick J. Grohar, John Glod, Cody J. Peer, Tristan M. Sissung, Fernanda I. Arnaldez, Lauren Long, William D. Figg, Patricia Whitcomb, Lee J. Helman, Brigitte C. Widemann
Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer
Litaty C. Mbatchi, Matthieu Gassiot, Philippe Pourquier, Alejando Goberna, Hakim Mahammedi, Loic Mourey, Florence Joly, Serge Lumbroso, Alexandre Evrard, Nadine Houede