Ausgabe 5/2016
Inhalt (23 Artikel)
The druggability of intracellular nucleotide-degrading enzymes
Chiara Rampazzo, Maria Grazia Tozzi, Charles Dumontet, Lars Petter Jordheim
The selective estrogen receptor modulators in breast cancer prevention
Fangxuan Li, Jinli Dou, Lijuan Wei, Shixia Li, Juntian Liu
Development of anti-angiogenic tyrosine kinases inhibitors: molecular structures and binding modes
Jingya Zhang, Linna Zhang, Yuanyou Wang, Guisen Zhao
Predicting survival of pancreatic cancer patients treated with gemcitabine using longitudinal tumour size data
Thierry Wendling, Hitesh Mistry, Kayode Ogungbenro, Leon Aarons
Bleomycin pharmacokinetics of bolus bleomycin dose in elderly cancer patients treated with electrochemotherapy
Ales Groselj, Mojca Krzan, Tina Kosjek, Masa Bosnjak, Gregor Sersa, Maja Cemazar
A phase II, open-label trial of bortezomib (VELCADE®) in combination with gemcitabine and cisplatin in patients with locally advanced or metastatic non-small cell lung cancer
E. Kontopodis, A. Kotsakis, N. Kentepozidis, K. Syrigos, N. Ziras, M. Moutsos, G. Filippa, A. Mala, L. Vamvakas, D. Mavroudis, V. Georgoulias, S. Agelaki
A phase II prospective study of the trastuzumab combined with 5-weekly S-1 and CDDP therapy for HER2-positive advanced gastric cancer
Hiromi Kataoka, Yoshinori Mori, Takaya Shimura, Hirotada Nishie, Makoto Natsume, Hisato Mochizuki, Yoshikazu Hirata, Satoshi Sobue, Takashi Mizushima, Hitoshi Sano, Yusuke Mizuno, Makoto Nakamura, Atsuyuki Hirano, Kenji Tsuchida, Kazunori Adachi, Kyoji Seno, Mika Kitagawa, Takashi Kawai, Takashi Joh
Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation
Fei Zhao, Jia Ming, Yan Zhou, Linjun Fan
Phase I dose escalation study of temsirolimus in combination with metformin in patients with advanced/refractory cancers
Muhammad R. Khawaja, Alpa M. Nick, Vinu Madhusudanannair, Siqing Fu, David Hong, Lacey M. McQuinn, Chaan S. Ng, Sarina A. Piha-Paul, Filip Janku, Vivek Subbiah, Apostolia Tsimberidou, Daniel Karp, Funda Meric-Bernstam, Karen H. Lu, Aung Naing
Role of adjuvant therapy after R0 resection for patients with distal cholangiocarcinoma
Young Saing Kim, In Gyu Hwang, Song-Ee Park, Se-Il Go, Jung-Hun Kang, Inkeun Park, Sung Yong Oh, Jun Ho Ji, Haa-Na Song, Se Hoon Park, Seung Tae Kim, Joon Oh Park
Population pharmacokinetic analysis of patritumab, a HER3 inhibitor, in subjects with advanced non-small cell lung cancer (NSCLC) or solid tumors
Satoshi Yoshiba, Mendel Jansen, Nobuko Matsushima, Shuquan Chen, Jeanne Mendell
A first-in-Asian phase 1 study to evaluate safety, pharmacokinetics and clinical activity of VS-6063, a focal adhesion kinase (FAK) inhibitor in Japanese patients with advanced solid tumors
Toshio Shimizu, Kazuya Fukuoka, Masayuki Takeda, Tutomu Iwasa, Takeshi Yoshida, Joanna Horobin, Mitchell Keegan, Lou Vaickus, Ajit Chavan, Mahesh Padval, Kazuhiko Nakagawa
Development of a skin rash within the first week and the therapeutic effect in afatinib monotherapy for EGFR-mutant non-small cell lung cancer (NSCLC): Okayama Lung Cancer Study Group experience
Kenichiro Kudo, Katsuyuki Hotta, Akihiro Bessho, Naoyuki Nogami, Toshiyuki Kozuki, Shoichi Kuyama, Koji Inoue, Shingo Harita, Toshiaki Okada, Kenichi Gemba, Masanori Fujii, Nagio Takigawa, Naohiro Oda, Mitsune Tanimoto, Katsuyuki Kiura
Changes in cross-sectional area of pulmonary vessels on chest computed tomography after chemotherapy in patients with advanced non-squamous non-small-cell lung cancer
Masato Karayama, Naoki Inui, Hideki Kusagaya, Seiichiro Suzuki, Yusuke Inoue, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Takafumi Suda
Analysis of a single-codon E746 deletion in exon 19 of the epidermal growth factor receptor
Masahito Ogasawara, Yutaka Nakamura, Naoto Morikawa, Hiroo Nitanai, Satoshi Moriguchi, Ryosuke Chiba, Heisuke Saito, Mika Ohta, Tatsuo Tanita, Tamotsu Sugai, Kazutaka Maeyama, Kohei Yamauchi, Yutaka Takaoka
Distinctive impact of pre-existing interstitial lung disease on the risk of chemotherapy-related lung injury in patients with lung cancer
Yuichi Ozawa, Daisuke Akahori, Keigo Koda, Takefumi Abe, Hirotsugu Hasegawa, Takashi Matsui, Masayuki Tanahashi, Hiroshi Niwa, Kazunari Yamada, Koshi Yokomura, Takafumi Suda
Sorafenib metabolism, transport, and enterohepatic recycling: physiologically based modeling and simulation in mice
Andrea N. Edginton, Eric I. Zimmerman, Aksana Vasilyeva, Sharyn D. Baker, John C. Panetta
Favorable outcome of primary mediastinal large B-cell lymphoma patients treated with sequential RCHOP-RICE regimen without radiotherapy
Neta Goldschmidt, Geffen Kleinstern, Marina Orevi, Ora Paltiel, Dina Ben-Yehuda, Alex Gural, Diana Libster, David Lavie, Moshe E Gatt
Silence of long noncoding RNA UCA1 inhibits malignant proliferation and chemotherapy resistance to adriamycin in gastric cancer
Chao Shang, Yan Guo, Jiaxing Zhang, Baojun Huang
Oral vinorelbine in combination with trastuzumab as a first-line therapy of metastatic or locally advanced HER2-positive breast cancer
Fadi Farhat, Joseph G. Kattan, Marwan Ghosn
A phase I dose escalation study of NK012, an SN-38 incorporating macromolecular polymeric micelle
Howard A. Burris, Jeffrey R. Infante, F. Anthony Greco, Dana S. Thompson, John H. Barton, Johanna C. Bendell, Yoshihiro Nambu, Noriko Watanabe, Suzanne F. Jones
The anti-angiogenic effect of dexamethasone in a murine hepatocellular carcinoma model by augmentation of gluconeogenesis pathway in malignant cells
Fei Shang, Mingming Liu, Bingwei Li, Xiaoyan Zhang, Youming Sheng, Shuying Liu, Jianqun Han, Hongwei Li, Ruijuan Xiu
Phase I clinical trial of lenalidomide in combination with bevacizumab in patients with advanced cancer
Rabih Said, Eugenia Kakadiaris, Sarina Piha-Paul, Siqing Fu, Gerald Falchook, Filip Janku, Jennifer J. Wheler, Ralph Zinner, David S. Hong, Razelle Kurzrock, Apostolia M. Tsimberidou