Ausgabe 6/2016
Inhalt (21 Artikel)
Overcoming treatment challenges in myelofibrosis and polycythemia vera: the role of ruxolitinib
Jeffrey C. Bryan, Srdan Verstovsek
Phase II trial of biweekly docetaxel, cisplatin, and 5-fluorouracil chemotherapy for advanced esophageal squamous cell carcinoma
Yoshihiro Tanaka, Kazuhiro Yoshida, Atsuko Yamada, Toshiyuki Tanahashi, Naoki Okumura, Nobuhisa Matsuhashi, Kazuya Yamaguchi, Tatsuhiko Miyazaki
Erratum to: Phase II trial of biweekly docetaxel, cisplatin, and 5-fluorouracil chemotherapy for advanced esophageal squamous cell carcinoma
Yoshihiro Tanaka, Kazuhiro Yoshida, Atsuko Yamada, Toshiyuki Tanahashi, Naoki Okumura, Nobuhisa Matsuhashi, Kazuya Yamaguchi, Tatsuhiko Miyazaki
A phase I study of binimetinib (MEK162) in Japanese patients with advanced solid tumors
K. Watanabe, S. Otsu, Y. Hirashima, R. Morinaga, K. Nishikawa, Y. Hisamatsu, T. Shimokata, M. Inada-Inoue, T. Shibata, H. Takeuchi, T. Watanabe, K. Tokushige, H. Maacke, K. Shiaro, Y. Ando
The combination of HLA-B*15:01 and DRB1*15:01 is associated with gemcitabine plus erlotinib-induced interstitial lung disease in patients with advanced pancreatic cancer
Meiko Nishimura, Masanori Toyoda, Kei Takenaka, Yoshinori Imamura, Naoko Chayahara, Naomi Kiyota, Toru Mukohara, Takeshi Kotake, Akihito Tsuji, Kosuke Saito, Yoshiro Saito, Hironobu Minami
Tanshinone I induces apoptosis and pro-survival autophagy in gastric cancers
Xiaoping Jing, Yichun Xu, Weiwei Cheng, Sheng Guo, Ya Zou, Li He
A meta-analysis identifies ERCC1 gene polymorphism as a predictor of better patient response to treatment with radiochemotherapy
Fengying Li, Xinyou Xie, Xiaobin Ren, Jun Zhang
Phase I study of safety and tolerability of sunitinib in combination with sirolimus in patients with refractory solid malignancies and determination of VEGF (VEGF-A) and soluble VEGF-R2 (sVEGFR2) in plasma
Jia Li, Harriet Kluger, Lesley Devine, James J. Lee, William Kevin Kelly, Linda Rink, Muhammad Wasif Saif
A phase 0 clinical trial of novel candidate extended-release formulations of capecitabine
Bart A.W. Jacobs, Jelte Meulenaar, Hilde Rosing, Dick Pluim, Matthijs M. Tibben, Niels de Vries, Bastiaan Nuijen, Alwin D.R. Huitema, Jos H. Beijnen, Jan H.M. Schellens, Serena Marchetti
Hypomagnesemia is a reliable predictor for efficacy of anti-EGFR monoclonal antibody used in combination with first-line chemotherapy for metastatic colorectal cancer
Hironori Fujii, Hirotoshi Iihara, Akio Suzuki, Ryo Kobayashi, Nobuhisa Matsuhashi, Takao Takahashi, Kazuhiro Yoshida, Yoshinori Itoh
YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo
De Cai, Zhiqing Qiu, Weimin Yao, Yuyu Liu, Haixiang Huang, Sihai Liao, Qun Luo, Liming Xie, Zhixiu Lin
Evaluation of artemisinins for the treatment of acute myeloid leukemia
Christina D. Drenberg, Jassada Buaboonnam, Shelley J. Orwick, Shuiying Hu, Lie Li, Yiping Fan, Anang A. Shelat, R. Kiplin Guy, Jeffrey Rubnitz, Sharyn D. Baker
Safety and efficacy of S-1 in combination with carboplatin in non-small cell lung cancer patients with interstitial lung disease: a pilot study
Akimasa Sekine, Hiroaki Satoh, Tomohisa Baba, Satoshi Ikeda, Ryo Okuda, Takeshi Shinohara, Shigeru Komatsu, Eri Hagiwara, Tae Iwasawa, Takashi Ogura, Terufumi Kato
A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors
Toshihiko Doi, Kohei Shitara, Takashi Kojima, Takayuki Yoshino, Aruna Dontabhaktuni, Hans Rebscher, Shande Tang, Jan Cosaert, Atsushi Ohtsu
Mechanism-based modeling of the clinical effects of bevacizumab and everolimus on vestibular schwannomas of patients with neurofibromatosis type 2
Aziz Ouerdani, Stéphane Goutagny, Michel Kalamarides, Iñaki F. Trocóniz, Benjamin Ribba
Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors
Johanna C. Bendell, Manish R. Patel, Kenichiro Yoshida, Jabed Seraj, Racquel Weaver, Charlotte Lemech, Thomas G. Todaro, Shubham Pant, Hendrik-Tobias Arkenau
Predictive value of GSTP1 Ile105Val polymorphism in clinical outcomes of chemotherapy in gastric and colorectal cancers: a systematic review and meta-analysis
Xiaobing Shen, Jia Wang, Xiaoluan Yan, Xiaofeng Ren, Fan Wang, Xiaowei Chen, Yuchao Xu
A comprehensive pharmacokinetic/pharmacodynamics analysis of the novel IGF1R/INSR inhibitor BI 893923 applying in vitro, in vivo and in silico modeling techniques
Melanie I. Titze, Otmar Schaaf, Marco H. Hofmann, Michael P. Sanderson, Stephan K. Zahn, Jens Quant, Thorsten Lehr
Phase II trial of concurrent bio-chemoradiotherapy using docetaxel, cisplatin, and cetuximab for locally advanced head and neck squamous cell carcinoma
Goshi Nishimura, Takahide Taguchi, Masahiro Takahashi, Osamu Shiono, Masanori Komatsu, Daisuke Sano, Kenichiro Yabuki, Yasuhiro Arai, Hideaki Takahashi, Masaharu Hata, Nobuhiko Oridate
Erratum to: Investigation of ototoxicity of artesunate as add-on therapy in patients with metastatic or locally advanced breast cancer: new audiological results from a prospective, open, uncontrolled, monocentric phase I study
Miriam König, Cornelia von Hagens, Sebastian Hoth, Ingo Baumann, Ingeborg Walter-Sack, Lutz Edler, Serkan Sertel