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Zeitschrift

Cancer Chemotherapy and Pharmacology

Cancer Chemotherapy and Pharmacology 6/2017

Ausgabe 6/2017

Inhaltsverzeichnis ( 24 Artikel )

28.04.2017 | Review Article | Ausgabe 6/2017

Neurotoxicity after high-dose methotrexate (MTX) is adequately explained by insufficient folinic acid rescue

Ian Joseph Cohen

19.04.2017 | Original Article | Ausgabe 6/2017 Open Access

Pharmacokinetics and safety of carfilzomib in patients with relapsed multiple myeloma and end-stage renal disease (ESRD): an open-label, single-arm, phase I study

Hang Quach, Darrell White, Andrew Spencer, P. Joy Ho, Divaya Bhutani, Mike White, Sandeep Inamdar, Chris Morris, Ying Ou, Martin Gyger

17.04.2017 | Original Article | Ausgabe 6/2017 Open Access

Gene expression levels of gamma-glutamyl hydrolase in tumor tissues may be a useful biomarker for the proper use of S-1 and tegafur-uracil/leucovorin in preoperative chemoradiotherapy for patients with rectal cancer

Sotaro Sadahiro, T. Suzuki, A. Tanaka, K. Okada, G. Saito, H. Miyakita, T. Ogimi, H. Nagase

20.04.2017 | Original Article | Ausgabe 6/2017

Induction chemotherapy followed by concurrent chemoradiotherapy vs. concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma: a retrospective cohort study

Jianyuan Zhang, Shaojun Chen, Guisheng Li, Weihua Zhang, Tingting Qin, Ping Yin, Haixin Huang, Hongwei Jiang

18.04.2017 | Original Article | Ausgabe 6/2017

A prospective comparison of intra-arterial chemotherapy combined with intravesical chemotherapy and intravesical chemotherapy alone after transurethral resection with a thulium laser in high-risk non-muscle invasive bladder cancer

Feng Sun, Ruizhe Zhao, Yiyong Zhu, Di Cui, Xiaohai Wang, Bangmin Han, Shengjie Liang, Haitao Liu, Xiaowen Sun, Fujun Zhao, Dongliang Xu, Shujie Xia

13.05.2017 | Original Article | Ausgabe 6/2017

UGT1A1 polymorphisms with irinotecan-induced toxicities and treatment outcome in Asians with Lung Cancer: a meta-analysis

Xuewei Chen, Liping Liu, Zhihua Guo, Wenhua Liang, Jiaxi He, Liyan Huang, Qiuhua Deng, Hailing Tang, Hui Pan, Minzhang Guo, Yang Liu, Qihua He, Jianxing He

19.04.2017 | Original Article | Ausgabe 6/2017

Assessment of drug–drug interaction potential between ceritinib and proton pump inhibitors in healthy subjects and in patients with ALK-positive non-small cell lung cancer

Yvonne Y. Lau, Wen Gu, Tiffany Lin, Kalyanee Viraswami-Appanna, Can Cai, Jeffrey W. Scott, Michael Shi

12.05.2017 | Original Article | Ausgabe 6/2017

CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis

Yen-Yun Wang, Yuk-Kwan Chen, Stephen Chu-Sung Hu, Ya-Ling Hsu, Chun-Hao Tsai, Tsung-Chen Chi, Wan-Ling Huang, Pei-Wen Hsieh, Shyng-Shiou F. Yuan

12.05.2017 | Original Article | Ausgabe 6/2017

Circularly permuted TRAIL plus thalidomide and dexamethasone versus thalidomide and dexamethasone for relapsed/refractory multiple myeloma: a phase 2 study

Yun Leng, Jian Hou, Jie Jin, Mei Zhang, Xiaoyan Ke, Bin Jiang, Ling Pan, Linhua Yang, Fang Zhou, Jianmin Wang, Zhao Wang, Li Liu, Wei Li, Zhixiang Shen, Lugui Qiu, Naibai Chang, Jianyong Li, Jing Liu, Hongyan Pang, Haitao Meng, Peng Wei, Hua Jiang, Yan Liu, Xiangjun Zheng, Shifang Yang, Wenming Chen

27.04.2017 | Original Article | Ausgabe 6/2017

Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy

Christopher P. Leamon, Joseph A. Reddy, Iontcho R. Vlahov, Ryan Dorton, Alicia Bloomfield, Marilynn Vetzel, Patrick J. Klein, Elaine Westrick, Le-cun Xu, Yu Wang

26.04.2017 | Original Article | Ausgabe 6/2017

Adjuvant concurrent chemoradiotherapy with low-dose daily cisplatin for extrahepatic bile duct cancer

Sang-Won Kim, O Kyu Noh, Ji Hun Kim, Mison Chun, Young-Taek Oh, Seok Yun Kang, Hyun Woo Lee, Rae Woong Park, Dukyong Yoon

27.04.2017 | Original Article | Ausgabe 6/2017

Phase 1b study of galunisertib in combination with gemcitabine in Japanese patients with metastatic or locally advanced pancreatic cancer

Masafumi Ikeda, Hideaki Takahashi, Shunsuke Kondo, Michael Mauritius Fabio Lahn, Ken Ogasawara, Karim A. Benhadji, Hisaki Fujii, Hideki Ueno

26.04.2017 | Original Article | Ausgabe 6/2017

Paclitaxel-induced sensory peripheral neuropathy is associated with an ABCB1 single nucleotide polymorphism and older age in Japanese

Yuko Tanabe, Chikako Shimizu, Akinobu Hamada, Kenji Hashimoto, Kazutaka Ikeda, Daisuke Nishizawa, Junko Hasegawa, Akihiko Shimomura, Yukinori Ozaki, Nobuko Tamura, Harukaze Yamamoto, Mayu Yunokawa, Kan Yonemori, Toshimi Takano, Hidetaka Kawabata, Kenji Tamura, Yasuhiro Fujiwara

26.04.2017 | Original Article | Ausgabe 6/2017

MITF suppression by CH5552074 inhibits cell growth in melanoma cells

Satoshi Aida, Yukiko Sonobe, Munehiro Yuhki, Kiyoaki Sakata, Toshihiko Fujii, Hiroshi Sakamoto, Takakazu Mizuno

27.04.2017 | Original Article | Ausgabe 6/2017

In vitro and in vivo assessments of two novel hydrazide compounds against breast cancer as well as mammary tumor cells

Elham Mousavi, Shahrzad Tavakolfar, Ali Almasirad, Zahra Kooshafar, Soudeh Dehghani, Ahoo Afsharinasab, Amir Amanzadeh, Samira Shafiee, Mona Salimi

10.05.2017 | Original Article | Ausgabe 6/2017 Open Access

FOXC1 overexpression is a marker of poor response to anthracycline-based adjuvant chemotherapy in sporadic triple-negative breast cancer

Y. L. Xu, R. Yao, J. Li, Y. D. Zhou, F. Mao, B. Pan, Q. Sun

28.04.2017 | Original Article | Ausgabe 6/2017

Phase II study of S-1 plus bevacizumab combination therapy for patients previously treated for non-squamous non-small cell lung cancer

Yu Nishijima-Futami, Seigo Minami, Shinji Futami, Taro Koba, Masayoshi Higashiguchi, Motohiro Tamiya, Hidekazu Suzuki, Tomonori Hirashima, Kiyoshi Komuta, Takashi Kijima

05.05.2017 | Original Article | Ausgabe 6/2017

A phase I study of cilengitide and paclitaxel in patients with advanced solid tumors

Tufia Haddad, Rui Qin, Ruth Lupu, Daniel Satele, Matthew Eadens, Matthew P. Goetz, Charles Erlichman, Julian Molina

28.04.2017 | Original Article | Ausgabe 6/2017

The incidence and risk factors of febrile neutropenia in chemotherapy-naïve lung cancer patients receiving etoposide plus platinum

Takumi Fujiwara, Hirotsugu Kenmotsu, Tateaki Naito, Takahisa Kawamura, Nobuaki Mamesaya, Mie Kotake, Haruki Kobayashi, Shota Omori, Kazuhisa Nakashima, Kazushige Wakuda, Akira Ono, Tetsuhiko Taira, Haruyasu Murakami, Katsuhiro Omae, Keita Mori, Masahiro Endo, Toshiaki Takahashi

11.05.2017 | Original Article | Ausgabe 6/2017

Accelerating drug development by efficiently using emerging PK/PD data from an adaptable entry-into-human trial: example of lumretuzumab

Georgina Meneses-Lorente, Christine McIntyre, Joy C. Hsu, Marlene Thomas, Wolfgang Jacob, Celine Adessi, Martin Weisser

12.05.2017 | Original Article | Ausgabe 6/2017

Reversing glioma malignancy: a new look at the role of antidepressant drugs as adjuvant therapy for glioblastoma multiforme

Anna M. Bielecka-Wajdman, Marta Lesiak, Tomasz Ludyga, Aleksander Sieroń, Ewa Obuchowicz

19.04.2017 | Clinical Trial Report | Ausgabe 6/2017

Phase I dose-escalation study of milciclib in combination with gemcitabine in patients with refractory solid tumors

Sandrine Aspeslagh, Kunwar Shailubhai, Rastilav Bahleda, Anas Gazzah, Andréa Varga, Antoine Hollebecque, Christophe Massard, Anna Spreafico, Michele Reni, Jean-Charles Soria

19.04.2017 | Short Communication | Ausgabe 6/2017

Pharmacodynamic effects in the cerebrospinal fluid of rats after intravenous administration of different asparaginase formulations

Andrea Ballerini, Federico Moro, Ilaria Fuso Nerini, Claudio Marcello Marzo, Angelo Di Clemente, Mariella Ferrari, Maurizio D’Incalci, Andrea Biondi, Antonella Colombini, Valentino Conter, Luca Porcu, Luigi Cervo, Carmelo Rizzari, Massimo Zucchetti

27.04.2017 | Short Communication | Ausgabe 6/2017

Hemodialysis does not impact axitinib exposure: clinical case of a patient with metastatic renal cell carcinoma

Antoine Thiery-Vuillemin, Emeline Orillard, Guillaume Mouillet, Fabien Calcagno, Nadège Devillard, Stéphane Bouchet, Bernard Royer

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