Ausgabe 6/2021
Inhalt (13 Artikel)
Renal toxicity of targeted therapies for renal cell carcinoma in patients with normal and impaired kidney function
Łukasz Mielczarek, Anna Brodziak, Paweł Sobczuk, Maciej Kawecki, Agnieszka Cudnoch-Jędrzejewska, Anna M. Czarnecka
Clinical pharmacology strategies in supporting drug development and approval of antibody–drug conjugates in oncology
Stephanie N. Liu, Chunze Li
Associations among plasma concentrations of regorafenib and its metabolites, adverse events, and ABCG2 polymorphisms in patients with metastatic colorectal cancers
Kazuo Kobayashi, Erika Sugiyama, Eiji Shinozaki, Takeru Wakatsuki, Masataka Tajima, Hiyori Kidokoro, Takeshi Aoyama, Yasuhiro Nakano, Kazuyoshi Kawakami, Koki Hashimoto, Mitsukuni Suenaga, Takashi Ichimura, Mariko Ogura, Keisho Chin, Izuma Nakayama, Akira Ooki, Daisuke Takahari, Wataru Suzuki, Takashi Yokokawa, Yuichi Minowa, Tomoko Hiraoka, Kenichi Suzuki, Hitoshi Sato, Toshihiro Hama, Kensei Yamaguchi
A phase I pharmacokinetic and safety study of Paclitaxel Injection Concentrate for Nano-dispersion (PICN) alone and in combination with carboplatin in patients with advanced solid malignancies and biliary tract cancers
Wen Wee Ma, Mojun Zhu, Elaine T. Lam, Jennifer R. Diamond, Grace K. Dy, George A. Fisher, Laura Williams Goff, Steven Alberts, Lynne A. Bui, Akhil Sanghal, Mudgal Kothekar, Ajay Khopade, Geetanjali Chimote, Robert Faulkner, S. Gail Eckhardt, Alex A. Adjei, Antonio Jimeno
Clinical significance of circulating tumor cells in the response to trastuzumab for HER2-negative metastatic gastric cancer
Daisuke Matsushita, Yoshikazu Uenosono, Takaaki Arigami, Shigehiro Yanagita, Keishi Okubo, Takashi Kijima, Futoshi Miyazono, Masahiro Hamanoue, Shuichi Hokita, Saburo Nakashima, Takao Ohtsuka, Shoji Natsugoe
Pharmacokinetics of UGN-101, a mitomycin-containing reverse thermal gel instilled via retrograde catheter for the treatment of low-grade upper tract urothelial carcinoma
Ahmad Shabsigh, Nir Kleinmann, Angela B. Smith, Douglas Scherr, Elyse Seltzer, Mark Schoenberg, Seth P. Lerner
A pharmacologically-based approach to high dose methotrexate administration to investigate nephrotoxicity and acute kidney injury biomarkers in children and adolescents with newly diagnosed osteosarcoma
Elizabeth Fox, Christine Busch, Alexander DeBernardo, Blair Segers, Joseph Gottschalk, Richard Womer, Naomi Balamuth, Rochelle Bagatell, Frank Balis
Venous thromboembolism incidence and risk factors in adults with acute lymphoblastic leukemia treated with and without pegylated E. coli asparaginase-containing regimens
Sarah M. Kashanian, Noa G. Holtzman, Ciera L. Patzke, Jonathan Cornu, Alison Duffy, Madhurima Koka, Sandrine Niyongere, Vu H. Duong, Maria R. Baer, Jummai Apata, Farin Kamangar, Ashkan Emadi
Foretinib induces G2/M cell cycle arrest, apoptosis, and invasion in human glioblastoma cells through c-MET inhibition
Narges K. Gortany, Ghodratollah Panahi, Homanaz Ghafari, Maryam Shekari, Mahmoud Ghazi-Khansari
Clinical utility of ABCB1 and ABCG2 genotyping for assessing the clinical and pathological response to FAC therapy in Mexican breast cancer patients
Eneida Turiján-Espinoza, Víctor Manuel Ruíz-Rodríguez, Edith Elena Uresti-Rivera, Ernesto Martínez-Leija, José de Jesús Zermeño-Nava, Arturo Guel-Pañola, Silvia Romano-Moreno, Juan Manuel Vargas-Morales, Diana Patricia Portales-Pérez
Pharmacokinetics of docetaxel and ritonavir after oral administration of ModraDoc006/r in patients with prostate cancer versus patients with other advanced solid tumours
Marit A. C. Vermunt, Lisa T. van der Heijden, Jeroen J. M. A. Hendrikx, Alfred H. Schinkel, Vincent A. de Weger, Eric van der Putten, Baukelien van Triest, Andries M. Bergman, Jos H. Beijnen
Switching from zoledronic acid to denosumab increases the risk for developing medication-related osteonecrosis of the jaw in patients with bone metastases
Hiroaki Ikesue, Kohei Doi, Mayu Morimoto, Masaki Hirabatake, Nobuyuki Muroi, Shinsuke Yamamoto, Toshihiko Takenobu, Tohru Hashida
Correction to: Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega‑3 polyunsaturated fatty acid eicosapentaenoic acid
Milene Volpato, Nicola Ingram, Sarah L Perry, Jade Spencer, Amanda D Race, Catriona Marshall, John M Hutchinson, Anna Nicolaou, Paul M Loadman, P Louise Coletta, Mark A Hull