Ausgabe 1/2021
Inhalt (21 Artikel)
Tumour microenvironment (TME) characterization identified prognosis and immunotherapy response in muscle-invasive bladder cancer (MIBC)
- Original Article
Rui Cao, Lushun Yuan, Bo Ma, Gang Wang, Ye Tian
Serum levels of the IL-6 family of cytokines predict prognosis in renal cell carcinoma (RCC)
- Open Access
- Original Article
Gigja Gudbrandsdottir, Helene H. Aarstad, Leif Bostad, Karin M. Hjelle, Hans J. Aarstad, Øystein Bruserud, Tor Henrik Anderson Tvedt, Christian Beisland
Potent anti-myeloma efficacy of dendritic cell therapy in combination with pomalidomide and programmed death-ligand 1 blockade in a preclinical model of multiple myeloma
- Original Article
Tan-Huy Chu, Manh-Cuong Vo, Hye-Seong Park, Thangaraj Jaya Lakshmi, Sung-Hoon Jung, Hyeoung-Joon Kim, Je-Jung Lee
Differential immune microenvironmental features of microsatellite-unstable colorectal cancers according to Fusobacterium nucleatum status
- Original Article
Ji Ae Lee, Seung-Yeon Yoo, Hyeon Jeong Oh, Seorin Jeong, Nam-Yun Cho, Gyeong Hoon Kang, Jung Ho Kim
Romidepsin (FK228) regulates the expression of the immune checkpoint ligand PD-L1 and suppresses cellular immune functions in colon cancer
- Open Access
- Original Article
Yehui Shi, Ying Fu, Xin Zhang, Gang Zhao, Yuan Yao, Yan Guo, Gang Ma, Shuai Bai, Hui Li
CD66b+ monocytes represent a proinflammatory myeloid subpopulation in cancer
- Original Article
Utku Horzum, Digdem Yoyen-Ermis, Ekim Z. Taskiran, Kerim Bora Yilmaz, Erhan Hamaloglu, Derya Karakoc, Gunes Esendagli
Body mass index and immune-related adverse events in patients on immune checkpoint inhibitor therapies: a systematic review and meta-analysis
- Original Article
Yuli Guzman-Prado, Jennifer Ben Shimol, Ondrej Samson
Characteristics of patients with EGFR-mutant non-small-cell lung cancer who benefited from immune checkpoint inhibitors
- Original Article
Eiki Ichihara, Daijiro Harada, Koji Inoue, Takuo Shibayama, Shinobu Hosokawa, Daizo Kishino, Shingo Harita, Nobuaki Ochi, Naohiro Oda, Naofumi Hara, Katsuyuki Hotta, Yoshinobu Maeda, Katsuyuki Kiura
Selective BET-bromodomain inhibition by JQ1 suppresses dendritic cell maturation and antigen-specific T-cell responses
- Original Article
Niklas Remke, Savita Bisht, Sebastian Oberbeck, Jens Nolting, Peter Brossart
Interleukin-38 promotes tumor growth through regulation of CD8+ tumor-infiltrating lymphocytes in lung cancer tumor microenvironment
- Original Article
Fumihiko Kinoshita, Tetsuzo Tagawa, Takaki Akamine, Kazuki Takada, Yuichi Yamada, Yuka Oku, Keisuke Kosai, Yuki Ono, Kensuke Tanaka, Sho Wakasu, Taro Oba, Atsushi Osoegawa, Mototsugu Shimokawa, Yoshinao Oda, Tomoaki Hoshino, Masaki Mori
ZFHX3 mutation as a protective biomarker for immune checkpoint blockade in non-small cell lung cancer
- Original Article
Jiexia Zhang, Ningning Zhou, Anqi Lin, Peng Luo, Xin Chen, Huojin Deng, Shijun Kang, Linlang Guo, Weiliang Zhu, Jian Zhang
TGF-βR inhibitor SB431542 restores immune suppression induced by regulatory B–T cell axis and decreases tumour burden in murine fibrosarcoma
- Original Article
Kavitha Premkumar, Bhavani S. Shankar
NF2 mutation status and tumor mutational burden correlate with immune cell infiltration in meningiomas
- Original Article
John W. Rutland, Corey M. Gill, Joshua Loewenstern, Hanane Arib, Margaret Pain, Melissa Umphlett, Yayoi Kinoshita, Russell B. McBride, Joshua Bederson, Michael Donovan, Robert Sebra, Raj K. Shrivastava, Mary Fowkes
Mechanism of action of a T cell-dependent bispecific antibody as a breakthrough immunotherapy against refractory colorectal cancer with an oncogenic mutation
- Open Access
- Original Article
Daisuke Kamakura, Ryutaro Asano, Hiroki Kawai, Masahiro Yasunaga
Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels tumour heterogeneity plus M2-like tumour-associated macrophage infiltration and aggressiveness in TNBC
- Original Article
Xuanwen Bao, Run Shi, Tianyu Zhao, Yanfang Wang, Natasa Anastasov, Michael Rosemann, Weijia Fang
Leukotriene receptor antagonists enhance HCC treatment efficacy by inhibiting ADAMs and suppressing MICA shedding
- Open Access
- Original Article
Jun Arai, Kaku Goto, Yumi Otoyama, Yoko Nakajima, Ikuya Sugiura, Atsushi Kajiwara, Masayuki Tojo, Yuki Ichikawa, Shojiro Uozumi, Yuu Shimozuma, Manabu Uchikoshi, Masashi Sakaki, Hisako Nozawa, Ryo Nakagawa, Ryosuke Muroyama, Naoya Kato, Hitoshi Yoshida
Human leukocyte antigen expression in paired primary lung tumors and brain metastases in non-small cell lung cancer
- Original Article
Jarrett J. Failing, Marie Christine Aubry, Aaron S. Mansfield
Patterns of progression in patients treated for immuno-oncology antibodies combination
- Original Article
Alice Bernard-Tessier, Capucine Baldini, Eduardo Castanon, Patricia Martin, Stéphane Champiat, Antoine Hollebecque, Sophie Postel-Vinay, Andreea Varga, Rastilav Bahleda, Anas Gazzah, Jean-Marie Michot, Vincent Ribrag, Jean-Pierre Armand, Aurélien Marabelle, Jean-Charles Soria, Christophe Massard, Samy Ammari
Impact of histamine H4 receptor deficiency on the modulation of T cells in a murine breast cancer model
- Original Article
Melisa B. Nicoud, Mónica A. Táquez Delgado, María de la Paz Sarasola, Agustina Vidal, Daniela Speisky, Graciela A. Cremaschi, Helena A. Sterle, Vanina A. Medina
Prediction of non-muscle-invasive bladder cancer recurrence during intravesical BCG immunotherapy by use of peripheral blood eosinophil count and percentage: a preliminary report
- Original Article
Mustafa Zafer Temiz, Aykut Colakerol, Ismail Ulus, Enes Kilic, Filip Paslanmaz, Sergen Sahin, Emrah Yuruk, Engin Kandirali, Atilla Semercioz, Ahmet Yaser Muslumanoglu
Identification of two distinct populations of WT1-specific cytotoxic T lymphocytes in co-vaccination of WT1 killer and helper peptides
- Original Article
Fumihiro Fujiki, Akihiro Tsuboi, Soyoko Morimoto, Naoya Hashimoto, Miki Inatome, Hiroko Nakajima, Jun Nakata, Sumiyuki Nishida, Kana Hasegawa, Naoki Hosen, Yoshihiro Oka, Yusuke Oji, Shinji Sogo, Haruo Sugiyama
