Ausgabe 10/2022
Inhalt (22 Artikel)
Engineering T-cells with chimeric antigen receptors to combat hematological cancers: an update on clinical trials
- Open Access
- Review Article
Maria Ormhøj, Hinrich Abken, Sine R. Hadrup
The nuclear transportation of PD-L1 and the function in tumor immunity and progression
- Review Article
Liyan Qu, Jiakang Jin, Jianan Lou, Chao Qian, Jinti Lin, Ankai Xu, Bing Liu, Man Zhang, Huimin Tao, Wei Yu
CMTM6 as a master regulator of PD-L1
- Review Article
Mahmoud Mohammad Yaseen, Nizar Mohammad Abuharfeil, Homa Darmani
Integrated analysis of single-cell and bulk RNA-sequencing identifies a signature based on B cell marker genes to predict prognosis and immunotherapy response in lung adenocarcinoma
- Original Article
Peng Song, Wenbin Li, Xiaoxuan Wu, Zhirong Qian, Jianming Ying, Shugeng Gao, Jie He
VSSP abrogates murine ovarian tumor-associated myeloid cell-driven immune suppression and induces M1 polarization in tumor-associated macrophages from ovarian cancer patients
- Original Article
ANM Nazmul H. Khan, Tiffany R. Emmons, William J. Magner, Emad Alqassim, Kelly L. Singel, Jason Ricciuti, Kevin H. Eng, Kunle Odunsi, Thomas B. Tomasi, Kelvin Lee, Scott I. Abrams, Circe Mesa, Brahm H. Segal
Penpulimab, an anti-PD1 IgG1 antibody in the treatment of advanced or metastatic upper gastrointestinal cancers
- Original Article
Yulong Zheng, Anna Rachelle Austria Mislang, Jermaine Coward, Rasha Cosman, Adam Cooper, Craig Underhill, Jianqing Zhu, Jianping Xiong, Ou Jiang, Hong Wang, Yanru Xie, Yuefen Zhou, Xiaoping Jin, Baiyong Li, Zhongmin Maxwell Wang, Kon Yew Kwek, Dennis Xia, Yu Xia, Nong Xu
Cellular and soluble immune checkpoint signaling forms PD-L1 and PD-1 in renal tumor tissue and in blood
- Open Access
- Original Article
Corinna U. Keber, Marcus Derigs, Carolin Schultz, Moritz Wegner, Susanne Lingelbach, Viktoria Wischmann, Rainer Hofmann, Carsten Denkert, Axel Hegele, Jörg Hänze
Transient 40 °C-shock potentiates cytotoxic responses of Vδ2+ γδ T cell via HSP70 upregulation
- Original Article
Li Lin, Yan Chen, Dan Chen, Junxiang Shu, Yi Hu, Zhinan Yin, Yangzhe Wu
Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors
- Original Article
Fyza Y. Shaikh, Joell J. Gills, Fuad Mohammad, James R. White, Courtney M. Stevens, Hua Ding, Juan Fu, Ada Tam, Richard L. Blosser, Jada C. Domingue, Tatianna C. Larman, Jamie E. Chaft, Jonathan D. Spicer, Joshua E. Reuss, Jarushka Naidoo, Patrick M. Forde, Sudipto Ganguly, Franck Housseau, Drew M. Pardoll, Cynthia L. Sears
Fc-independent functions of anti-CTLA-4 antibodies contribute to anti-tumor efficacy
- Open Access
- Original Article
Yosuke Sato, Cierra N. Casson, Atsushi Matsuda, James I. Kim, Judy Qiuju Shi, Shinji Iwasaki, Susan Chen, Brett Modrell, Chingkit Chan, Daniel Tavares, Douglas Austen, Koh Ida, Olga Tayber, Pyae Hein, Robert Comeau, Yafang Lin, Michael H. Shaw
Enhancement of CD70-specific CAR T treatment by IFN-γ released from oHSV-1-infected glioblastoma
- Original Article
Guidong Zhu, Junwen Zhang, Qing Zhang, Guishan Jin, Xiaodong Su, Sisi Liu, Fusheng Liu
Comprehensive analyses of prognostic biomarkers and immune infiltrates among histone lysine demethylases (KDMs) in hepatocellular carcinoma
- Original Article
Li-Hua Qu, Qian Fang, Tong Yin, Hui-Mei Yi, Guang-Bo Mei, Zi-Zhan Hong, Xue-Bing Qiu, Rui Zhou, Hui-Fen Dong
Immunosuppressive properties of human PD-1 + , PDL-1 + and CD80 + dendritic cells from lymph nodes aspirates of lung cancer patients
- Original Article
Iwona Kwiecień, Elżbieta Rutkowska, Agata Raniszewska, Rafał Sokołowski, Joanna Bednarek, Karina Jahnz-Różyk, Piotr Rzepecki, Joanna Domagała-Kulawik
Avelumab in paediatric patients with refractory or relapsed solid tumours: dose-escalation results from an open-label, single-arm, phase 1/2 trial
- Open Access
- Original Article
David M. Loeb, Ji Won Lee, Daniel A. Morgenstern, Yvan Samson, Anne Uyttebroeck, Chuhl Joo Lyu, An Van Damme, Karsten Nysom, Margaret E. Macy, Alexandra P. Zorzi, Julia Xiong, Petra Pollert, Ingrid Joerg, Yulia Vugmeyster, Mary Ruisi, Hyoung Jin Kang
Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells
- Original Article
Jutatip Panaampon, Ryusho Kariya, Seiji Okada
Immunosuppressive TREM2(+) macrophages are associated with undesirable prognosis and responses to anti-PD-1 immunotherapy in non-small cell lung cancer
- Original Article
Hongyu Zhang, Zilong Liu, Haoyu Wen, Yifan Guo, Fengkai Xu, Qiaoliang Zhu, Wei Yuan, Rongkui Luo, Chunlai Lu, Ronghua Liu, Jie Gu, Di Ge
Tumour cell-activated platelets modulate the immunological activity of CD4+, CD8+, and NK cells, which is efficiently antagonized by heparin
- Open Access
- Original Article
Lukas M. Gockel, Katrin Nekipelov, Vito Ferro, Gerd Bendas, Martin Schlesinger
Immune epitopes identification and designing of a multi-epitope vaccine against bovine leukemia virus: a molecular dynamics and immune simulation approaches
- Original Article
Abdus Samad, Nigar Sultana Meghla, Zulkar Nain, Tomasz M. Karpiński, Md. Shahedur Rahman
Targeting PD-L1 and TIGIT could restore intratumoral CD8 T cell function in human colorectal cancer
- Original Article
Marion Thibaudin, Emeric Limagne, Léa Hampe, Elise Ballot, Caroline Truntzer, Francois Ghiringhelli
Parvimonas micra is associated with tumour immune profiles in molecular subtypes of colorectal cancer
- Open Access
- Original Article
Thyra Löwenmark, Xingru Li, Anna Löfgren-Burström, Carl Zingmark, Agnes Ling, Therese G. Kellgren, Pär Larsson, Ingrid Ljuslinder, Sun Nyunt Wai, Sofia Edin, Richard Palmqvist
Correction to: Functional virus‑specific memory T cells survey glioblastoma
- Correction
Jianfang Ning, Noah V. Gavil, Shaoping Wu, Sathi Wijeyesinghe, Eyob Weyu, Jun Ma, Ming Li, Florina‑Nicoleta Grigore, Sanjay Dhawan, Alexander G. J. Skorput, Shawn C. Musial, Clark C. Chen, David Masopust, Pamela C. Rosato
Correction to: Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden
- Open Access
- Correction
Julia Femel, Luuk van Hooren, Melanie Herre, Jessica Cedervall, Falk Saupe, Elisabeth J. M. Huijbers, Danielle R. J. Verboogen, Matthias Reichel, Victor L. Thijssen, Arjan W. Griffioen, Lars Hellman, Anna Dimberg, Anna-Karin Olsson
