Ausgabe 11/2018
Inhalt (15 Artikel)
TIGIT: a novel immunotherapy target moving from bench to bedside
Benjamin L. Solomon, Ignacio Garrido-Laguna
PD-1/PD-L1 co-inhibition shapes anticancer T cell immunodominance: facing the consequences of an immunological ménage à trois
S. M. Mansour Haeryfar, Todd D. Schell
Increased Tim-3+ T cells in PBMCs during nivolumab therapy correlate with responses and prognosis of advanced esophageal squamous cell carcinoma patients
Ryo Kato, Makoto Yamasaki, Shinya Urakawa, Kentaro Nishida, Tomoki Makino, Akiko Morimoto-Okazawa, Atsunari Kawashima, Kota Iwahori, Susumu Suzuki, Ryuzo Ueda, Masaki Mori, Taroh Satoh, Yuichiro Doki, Hisashi Wada
Expression of the inhibitory B7 family molecule VISTA in human colorectal carcinoma tumors
Shan Xie, Jia Huang, Qin Qiao, Wenjuan Zang, Shanjuan Hong, Haidong Tan, Chen Dong, Zhiying Yang, Ling Ni
IL-10 inducible CD8+ regulatory T-cells are enriched in patients with multiple myeloma and impact the generation of antigen-specific T-cells
Julian Plaumann, Melanie Engelhardt, Mohamed H. S. Awwad, Hakim Echchannaoui, Eva Amman, Marc S. Raab, Jens Hillengass, Niels Halama, Brigitte Neuber, Carsten Müller-Tidow, Hartmut Goldschmidt, Michael Hundemer
Determination of optimum vitamin D3 levels for NK cell-mediated rituximab- and obinutuzumab-dependent cellular cytotoxicity
Frank Neumann, Fabian Acker, Claudia Schormann, Michael Pfreundschuh, Joerg Thomas Bittenbring
TCR repertoire profiling of tumors, adjacent normal tissues, and peripheral blood predicts survival in nasopharyngeal carcinoma
Ya-bin Jin, Wei Luo, Guo-yi Zhang, Kai-rong Lin, Jin-huan Cui, Xiang-ping Chen, Ying-ming Pan, Xiao-fan Mao, Jun Tang, Yue-jian Wang
Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung
Matthew P. Alexander, Steven N. Fiering, Gary R. Ostroff, Robert A. Cramer, David W. Mullins
Circulating CD8+ T-cell repertoires reveal the biological characteristics of tumors and clinical responses to chemotherapy in breast cancer patients
Kai-Rong Lin, Dan-Mei Pang, Ya-Bin Jin, Qian Hu, Ying-Ming Pan, Jin-Huan Cui, Xiang-Ping Chen, Yin-Xin Lin, Xiao-Fan Mao, Hai-Bo Duan, Wei Luo
Chemotherapy-induced apoptosis, autophagy and cell cycle arrest are key drivers of synergy in chemo-immunotherapy of epithelial ovarian cancer
John Wahba, Marina Natoli, Lynsey M. Whilding, Ana C. Parente-Pereira, Youngrock Jung, Stefania Zona, Eric W.-F. Lam, J. Richard Smith, John Maher, Sadaf Ghaem-Maghami
T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient
Andreas Wieland, Alice O. Kamphorst, N. Volkan Adsay, Jonathan J. Masor, Juan Sarmiento, Tahseen H. Nasti, Sam Darko, Daniel C. Douek, Yue Xue, Walter J. Curran, David H. Lawson, Rafi Ahmed
Molecular subgroups and B7-H4 expression levels predict responses to dendritic cell vaccines in glioblastoma: an exploratory randomized phase II clinical trial
Yu Yao, Feifei Luo, Chao Tang, Dikang Chen, Zhiyong Qin, Wei Hua, Ming Xu, Ping Zhong, Shuangquan Yu, Di Chen, Xiaojie Ding, Yi Zhang, Xiujuan Zheng, Jiao Yang, Jiawen Qian, Yuting Deng, Dave S. B. Hoon, Jian Hu, Yiwei Chu, Liangfu Zhou
Microenvironmental derived factors modulating dendritic cell function and vaccine efficacy: the effect of prostanoid receptor and nuclear receptor ligands
Tonke K. Raaijmakers, Marleen Ansems
Oncogenic MYD88 mutations in lymphoma: novel insights and therapeutic possibilities
Alexander N. R. Weber, Yamel Cardona Gloria, Özcan Çınar, H. Christian Reinhardt, Antonio Pezzutto, Olaf-Oliver Wolz
International Symposium: Trailblazing in Cancer Immunotherapy, October 29–31, 2017, Pamplona, Spain
Pedro Berraondo, Maria Angela Aznar, Elisabeth Perez-Ruiz, Maria Esperanza Rodriguez-Ruiz, Eduardo Castañon, Jose Luis Perez-Gracia, Ignacio Melero