Ausgabe 12/2019
Inhalt (15 Artikel)
Autophagy inhibition induces the repolarisation of tumour-associated macrophages and enhances chemosensitivity of laryngeal cancer cells to cisplatin in mice
Ying Guo, Yufang Feng, Xinhua Cui, Qirong Wang, Xinliang Pan
Pembrolizumab for anaplastic thyroid cancer: a case study
Marra Jai Aghajani, Adam Cooper, Helen McGuire, Thomas Jeffries, Jawad Saab, Kasim Ismail, Paul de Souza, Victoria Bray, Barbara Fazekas de St Groth, Navin Niles, Tara Laurine Roberts
Regulatory T cells induce CD4− NKT cell anergy and suppress NKT cell cytotoxic function
Fumie Ihara, Daiju Sakurai, Mariko Takami, Toshiko Kamata, Naoki Kunii, Kazuki Yamasaki, Tomohisa Iinuma, Toshinori Nakayama, Shinichiro Motohashi, Yoshitaka Okamoto
Combining alpha radiation-based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor-specific long-term immune response
Vered Domankevich, Adi Cohen, Margalit Efrati, Michael Schmidt, Hans-Georg Rammensee, Sujit S. Nair, Ashutosh Tewari, Itzhak Kelson, Yona Keisari
Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma
Yaping Xu, Fei Fang, Hui Jiao, Xiaohui Zheng, Liyue Huang, Xue Yi, Wenxiu Zhao
Identification of prognostic genes in the acute myeloid leukemia immune microenvironment based on TCGA data analysis
Haimeng Yan, Jianwei Qu, Wen Cao, Yang Liu, Gaofeng Zheng, Enfan Zhang, Zhen Cai
Preclinical development of T-cell receptor-engineered T-cell therapy targeting the 5T4 tumor antigen on renal cell carcinoma
Yuexin Xu, Alicia J. Morales, Michael J. Cargill, Andrea M. H. Towlerton, David G. Coffey, Edus H. Warren, Scott S. Tykodi
Predominance of M2 macrophages in gliomas leads to the suppression of local and systemic immunity
Aurobind Vidyarthi, Tapan Agnihotri, Nargis Khan, Sanpreet Singh, Manoj K. Tewari, Bishan D. Radotra, Deepyan Chatterjee, Javed N. Agrewala
Serum very long-chain fatty acid-containing lipids predict response to immune checkpoint inhibitors in urological cancers
Andreas Mock, Stefanie Zschäbitz, Romy Kirsten, Matthias Scheffler, Barbara Wolf, Christel Herold-Mende, Rebecca Kramer, Elena Busch, Maximilian Jenzer, Dirk Jäger, Carsten Grüllich
Tumor genetic alterations and features of the immune microenvironment drive myelodysplastic syndrome escape and progression
Paola Montes, Mónica Bernal, Laura N. Campo, Amanda Rocío González-Ramírez, Pilar Jiménez, Pilar Garrido, Manuel Jurado, Federico Garrido, Francisco Ruiz-Cabello, Francisca Hernández
ISG15 pathway knockdown reverses pancreatic cancer cell transformation and decreases murine pancreatic tumor growth via downregulation of PDL-1 expression
Julian Burks, Alia Fleury, Sarah Livingston, Jill P. Smith
PD-1+ TIGIT+ CD8+ T cells are associated with pathogenesis and progression of patients with hepatitis B virus-related hepatocellular carcinoma
Xiaoli Liu, Mengge Li, Xinhui Wang, Zhibo Dang, Yuyong Jiang, Xianbo Wang, Yaxian Kong, Zhiyun Yang
Role of regulatory T cells and checkpoint inhibition in hepatocellular carcinoma
Bettina Langhans, Hans Dieter Nischalke, Benjamin Krämer, Leona Dold, Philipp Lutz, Raphael Mohr, Annabelle Vogt, Marieta Toma, Anna Maria Eis-Hübinger, Jacob Nattermann, Christian P. Strassburg, Maria Angeles Gonzalez-Carmona, Ulrich Spengler
Tumor-associated macrophages expressing galectin-9 identify immunoevasive subtype muscle-invasive bladder cancer with poor prognosis but favorable adjuvant chemotherapeutic response
Yangyang Qi, Yuan Chang, Zewei Wang, Lingli Chen, Yunyi Kong, Peipei Zhang, Zheng Liu, Quan Zhou, Yifan Chen, Jiajun Wang, Qi Bai, Yu Xia, Li Liu, Yu Zhu, Le Xu, Bo Dai, Jianming Guo, Yiwei Wang, Jiejie Xu, Weijuan Zhang
Histone deacetylase inhibition promotes intratumoral CD8+ T-cell responses, sensitizing murine breast tumors to anti-PD1
Tyler R. McCaw, Mei Li, Dmytro Starenki, Mingyong Liu, Sara J. Cooper, Rebecca C. Arend, Andres Forero, Donald J. Buchsbaum, Troy D. Randall