Ausgabe 12/2024
Inhalt (27 Artikel)
Tumor immunogenicity regulates host immune responses, and conventional dendritic cell type 2 uptakes the majority of tumor antigens in an orthotopic lung cancer model
- Open Access
- Brief Report
Ki-Hyun Kim, Seung-jae Kim, Jacob D. Eccles, Christian Ascoli, Gye Young Park
The relevance of tumor target expression levels on IgA-mediated cytotoxicity in cancer immunotherapy
- Open Access
- Research
Chilam Chan, Núria Casalé Cabanes, J. H. Marco Jansen, Joël Guillaume, Maaike Nederend, Elsemieke M. Passchier, Valentina E. Gómez-Mellado, Matthias Peipp, Marianne Boes, Geert van Tetering, Jeanette H. W. Leusen
INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: a potential application to increase the efficacy of NK adoptive cell therapy against cancer
- Open Access
- Research
Melissa Maxwell, Dingxue Yan, Brianna Rivest, Andrew Boone, James Cardia, Elfriede Noessner
Efficacy and safety of lenvatinib combined with anti-PD-1 antibodies plus GEMOX chemotherapy as non-first-line systemic therapy in advanced gallbladder cancer
- Open Access
- Research
Yang Tan, Kai Liu, Chengpei Zhu, Shanshan Wang, Yunchao Wang, Jingnan Xue, Cong Ning, Nan Zhang, Jiashuo Chao, Longhao Zhang, Junyu Long, Xiaobo Yang, Daobing Zeng, Lijin Zhao, Haitao Zhao
A random survival forest-based pathomics signature classifies immunotherapy prognosis and profiles TIME and genomics in ES-SCLC patients
- Open Access
- Research
Yuxin Jiang, Yueying Chen, Qinpei Cheng, Wanjun Lu, Yu Li, Xueying Zuo, Qiuxia Wu, Xiaoxia Wang, Fang Zhang, Dong Wang, Qin Wang, Tangfeng Lv, Yong Song, Ping Zhan
Therapeutic antibodies in oncology: an immunopharmacological overview
- Open Access
- Review
Karen Toledo-Stuardo, Carolina H. Ribeiro, Fabiola González-Herrera, Douglas J. Matthies, María Soledad Le Roy, Claudio Dietz-Vargas, Yesenia Latorre, Ivo Campos, Yuneisy Guerra, Samantha Tello, Valeria Vásquez-Sáez, Pedro Novoa, Nicolás Fehring, Mauricio González, Jose Rodríguez-Siza, Gonzalo Vásquez, Pamela Méndez, Claudia Altamirano, María Carmen Molina
Dose-escalation, tolerability, and efficacy of intratumoral and subcutaneous injection of hemagglutinating virus of Japan envelope (HVJ-E) against chemotherapy-resistant malignant pleural mesothelioma: a clinical trial
- Open Access
- Research
Kazuma Sakura, Muneyoshi Kuroyama, Yasushi Shintani, Soichiro Funaki, Shinji Atagi, Yoshihisa Kadota, Kozo Kuribayashi, Takashi Kijima, Takashi Nakano, Toshihiro Nakajima, Masao Sasai, Meinoshin Okumura, Yasufumi Kaneda
Toripalimab combined with definitive chemoradiotherapy for locally advanced cervical squamous cell carcinoma patients (TRACE): A single-arm, phase I/II trial
- Open Access
- Research
Dan Ou, Rong Cai, Wei-Xiang Qi, Can Cui, Lu Cao, Shu-Bei Wang, Huan Li, Tao Ma, Ying Miao, Cheng Xu, Gang Cai, Wei-Guo Cao, Yun-Sheng Gao, Jia-Yi Chen, Hao-Ping Xu
NitraTh epitope-based neoantigen vaccines for effective tumor immunotherapy
- Open Access
- Research
Wanli Zhang, Xupeiyao Shi, Shitong Huang, Qiumin Yu, Zijie Wu, Wenbin Xie, Binghua Li, Yanchao Xu, Zheng Gao, Guozhi Li, Qianqian Qian, Tiandi He, Jiaxue Zheng, Tingran Zhang, Yue Tong, Danni Deng, Xiangdong Gao, Hong Tian, Wenbing Yao
Development and validation of a new tool to estimate early mortality in patients with advanced cancer treated with immunotherapy
- Open Access
- Research
Andrea De Giglio, Alessandro Leonetti, Francesca Comito, Daria Maria Filippini, Veronica Mollica, Karim Rihawi, Marianna Peroni, Giulia Mazzaschi, Ilaria Ricciotti, Francesca Carosi, Andrea Marchetti, Matteo Rosellini, Ambrogio Gagliano, Valentina Favorito, Elisabetta Nobili, Francesco Gelsomino, Barbara Melotti, Paola Valeria Marchese, Francesca Sperandi, Alessandro Di Federico, Sebastiano Buti, Fabiana Perrone, Francesco Massari, Maria Abbondanza Pantaleo, Marcello Tiseo, Andrea Ardizzoni
HLA-G neo-expression modifies genetic programs governing tumor cell lines
- Open Access
- Research
Diana Tronik-Le Roux, Marina Daouya, Isabelle Poras, François Desgrandchamps, Edgardo D. Carosella
Enhanced anti-tumor efficacy of electroporation (EP)-mediated DNA vaccine boosted by allogeneic lymphocytes in pre-established tumor models
- Open Access
- Research
Sanyuan Shi, Luchen Zhang, Anjie Zheng, Fang Xie, Samuel Kesse, Yang Yang, Jinliang Peng, Yuhong Xu
Effectiveness, safety, and biomarker analysis of lenvatinib plus toripalimab as chemo-free therapy in advanced intrahepatic cholangiocarcinoma: a real-world study
- Open Access
- Research
Shanshan Wang, Jiashuo Chao, Hao Wang, Shuofeng Li, Yunchao Wang, Chengpei Zhu, Nan Zhang, Mingjian Piao, Xu Yang, Kai Liu, Ziyu Xun, Xinting Sang, Xiaobo Yang, Weidong Duan, Haitao Zhao
Multi-omics analysis and response prediction of PD-1 monoclonal antibody containing regimens in patients with relapsed/refractory diffuse large B-cell lymphoma
- Open Access
- Research
Xinrui Chen, Yan Qin, Xuemin Xue, Zucheng Xie, Tongji Xie, Liling Huang, Haohua Zhu, Lina Gao, Jiangtao Li, Jianliang Yang, Lin Gui, Sheng Yang, Haizhu Chen, Xiaoli Feng, Yuankai Shi
Exploring the impact of durvalumab on biliary tract cancer: insights from real-world clinical data
- Open Access
- Research
Patrick Reimann, Ilektra-Antonia Mavroeidi, Jonathan Burghofer, Hossein Taghizadeh, Gerald Webersinke, Stefan Kasper, Georg Schreil, Darius Morariu, Andreas Reichinger, Hideo Andreas Baba, Patrick Kirchweger, Martin Schuler, Angela Djanani, Gerald W. Prager, Holger Rumpold, Magdalena Benda, Eva-Maria Schneider, Sylvia Mink, Thomas Winder, Bernhard Doleschal
Immunotherapy may be more appropriate for ERBB2 low-expressing extramammary paget’s disease patients: a prognosis analysis and exploration of targeted therapy and immunotherapy of extramammary paget’s disease patients
- Open Access
- Research
Jiawen Yang, Yurong Chen, Xiuyuan Zhang, Ziyan Tong, Shanshan Weng, Ning Zhu, Ying Yuan
GPCRs: emerging targets for novel T cell immune checkpoint therapy
- Open Access
- Review
Kaitlyn Dickinson, Elliott J. Yee, Isaac Vigil, Richard D. Schulick, Yuwen Zhu
PD-L1+ neutrophils induced NETs in malignant ascites is a potential biomarker in HCC
- Open Access
- Research
Xiaoyu Sun, Yaoqi Gui, Tai Yang, Lingbing Chen, Yi Zhang, Ling Yan, Weixian Chen, Bo Wang
PD-1 blockade does not improve efficacy of EpCAM-directed CAR T-cell in lung cancer brain metastasis
- Open Access
- Research
Jens Blobner, Laura Dengler, Constantin Eberle, Julika J. Herold, Tao Xu, Alexander Beck, Anton Mühlbauer, Katharina J. Müller, Nico Teske, Philipp Karschnia, Dominic van den Heuvel, Ferdinand Schallerer, Hellen Ishikawa-Ankerhold, Niklas Thon, Joerg-Christian Tonn, Marion Subklewe, Sebastian Kobold, Patrick N. Harter, Veit R. Buchholz, Louisa von Baumgarten
Antitumor effects of intracranial injection of B7-H3-targeted Car-T and Car-Nk cells in a patient-derived glioblastoma xenograft model
- Open Access
- Research
Tetsuro Tachi, Noriyuki Kijima, Hideki Kuroda, Syunya Ikeda, Koki Murakami, Tomoyoshi Nakagawa, Moto Yaga, Kanji Nakagawa, Reina Utsugi, Ryuichi Hirayama, Yoshiko Okita, Naoki Kagawa, Haruhiko Kishima, Chihaya Imai, Naoki Hosen
Integrative analyses of bulk and single-cell RNA-seq reveals the correlation between SPP1+ macrophages and resistance to neoadjuvant chemoimmunotherapy in esophageal squamous cell carcinoma
- Open Access
- Research
Zhenyang Geng, Feng Li, Zhichang Yang, Bowen Li, Yifan Xu, Bin Wu, Yinliang Sheng, Ping Yuan, Lan Huang, Yu Qi
Correction to: Development of nomograms to predict therapeutic response and prognosis of non-small cell lung cancer patients treated with anti-PD-1 antibody
- Open Access
- Correction
Shijin Yuan, Yan Xia, Lihong Shen, Liuqing Ye, Lisha Li, Lifen Chen, Xinyou Xie, Haizhou Lou, Jun Zhang
Increased myositis and possible myocarditis in melanoma patients treated with immune checkpoint inhibitors in the COVID-19 era
- Open Access
- Brief Report
Allison L. Gradone, Vincent T. Ma, Alexi Vasbinder, Leslie A. Fecher, Sarah Yentz, Salim S. Hayek, Christopher D. Lao
Biomarker role of thyroid irAE and PD-L1 positivity in predicting PD-1 blockade efficacy in patients with non-small cell lung cancer
- Open Access
- Research
Hye In Kim, Won Gu Kim, Mijin Kim, Nak Gyeong Ko, Mihyeon Jin, Hyun Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Yoon-La Choi, Min Ji Jeon, Tae Yong Kim, Won Bae Kim, Sang-We Kim, Dae Ho Lee, Se Jin Jang, Sun Wook Kim, Jae Hoon Chung, Tae Hyuk Kim, Se-Hoon Lee
Optimizing cancer classification: a hybrid RDO-XGBoost approach for feature selection and predictive insights
- Open Access
- Research
Abrar Yaqoob, Navneet Kumar Verma, Rabia Musheer Aziz, Mohd Asif Shah
Efficacy and safety of perioperative immunotherapy combinations for resectable non-small cell lung cancer: a systematic review and network meta-analysis
- Open Access
- Review
Yuelin Han, Xiangtian Xiao, Tingting Qin, Shuxi Yao, Xinyue Liu, Yanqi Feng, Zhou Li, Yiming Li, Shu Xia
Correction to: Efficacy and safety of anti‑PD‑1/PD‑L1‑based dual immunotherapies versus PD‑1/PD‑L1 inhibitor alone in patients with advanced solid tumor: a systematic review and meta‑analysis
- Open Access
- Correction
Yueying Chen, Hedong Han, Jing Cheng, Qinpei Cheng, Suhua Zhu, Ping Zhan, Hongbing Liu, ·Yong Song, Tangfeng Lv
