Ausgabe 2/2019
Inhalt (15 Artikel)
Histamine targets myeloid-derived suppressor cells and improves the anti-tumor efficacy of PD-1/PD-L1 checkpoint blockade
- Open Access
- Original Article
Hanna Grauers Wiktorin, Malin S. Nilsson, Roberta Kiffin, Frida Ewald Sander, Brianna Lenox, Anna Rydström, Kristoffer Hellstrand, Anna Martner
The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth
- Original Article
Tyler R. McCaw, Mei Li, Dmytro Starenki, Sara J. Cooper, Mingyong Liu, Selene Meza-Perez, Rebecca C. Arend, Donald J. Buchsbaum, Andres Forero, Troy D. Randall
INT-HA induces M2-like macrophage differentiation of human monocytes via TLR4-miR-935 pathway
- Original Article
Boke Zhang, Yan Du, Yiqing He, Yiwen Liu, Guoliang Zhang, Cuixia Yang, Feng Gao
Inhibitory functions of PD-L1 and PD-L2 in the regulation of anti-tumor immunity in murine tumor microenvironment
- Original Article
Daisuke Umezu, Nana Okada, Yukimi Sakoda, Keishi Adachi, Toshiyasu Ojima, Hiroki Yamaue, Masatoshi Eto, Koji Tamada
Analysis of tumor-infiltrating CD103 resident memory T-cell content in recurrent laryngeal squamous cell carcinoma
- Original Article
Jacqueline E. Mann, Joshua D. Smith, Andrew C. Birkeland, Emily Bellile, Paul Swiecicki, Michelle Mierzwa, Steven B. Chinn, Andrew G. Shuman, Kelly M. Malloy, Keith A. Casper, Scott A. McLean, Jeffery S. Moyer, Gregory T. Wolf, Carol R. Bradford, Mark E. Prince, Thomas E. Carey, Jonathan B. McHugh, Matthew E. Spector, J. Chad Brenner
Stromal interleukin-33 promotes regulatory T cell-mediated immunosuppression in head and neck squamous cell carcinoma and correlates with poor prognosis
- Original Article
Yi-hui Wen, Han-qing Lin, Hang Li, Yi Zhao, Vivian Wai Yan Lui, Lin Chen, Xing-mei Wu, Wei Sun, Wei-ping Wen
Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy
- Original Article
Laura A. Vitale, Lawrence J. Thomas, Li-Zhen He, Thomas O’Neill, Jenifer Widger, Andrea Crocker, Karuna Sundarapandiyan, James R. Storey, Eric M. Forsberg, Jeffrey Weidlick, April R. Baronas, Lauren E. Gergel, James M. Boyer, Crystal Sisson, Joel Goldstein, Henry C. Marsh Jr., Tibor Keler
The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design
- Open Access
- Original Article
Matthieu Besneux, Alexander Greenshields-Watson, Martin J. Scurr, Bruce J. MacLachlan, Adam Christian, Michael M. Davies, Rachel Hargest, Simon Phillips, Andrew Godkin, Awen Gallimore
Hyperresponsiveness to interferon gamma exposure as a response mechanism to anti-PD-1 therapy in microsatellite instability colorectal cancer
- Original Article
Wenli Yuan, Deyao Deng, Hongchao Jiang, Changling Tu, Xueqin Shang, Hongchun He, Ruize Niu, Jian Dong
Targeting the polarization of tumor-associated macrophages and modulating mir-155 expression might be a new approach to treat diffuse large B-cell lymphoma of the elderly
- Original Article
Wagner A. Poles, Erika E. Nishi, Mariana B. de Oliveira, Angela I. P. Eugênio, Tathiana A. de Andrade, Antonio Hugo F. M. Campos, Ruy R. de Campos Jr., José Vassallo, Antonio C. Alves, Cristovam Scapulatempo Neto, Roberto Antonio Pinto Paes, Gilles Landman, Maria Cláudia N. Zerbini, Gisele W. B. Colleoni
Upregulation of tumor PD-L1 by neoadjuvant chemoradiotherapy (neoCRT) confers improved survival in patients with lymph node metastasis of locally advanced rectal cancers
- Original Article
Shu-Fen Chiang, Chih-Yang Huang, Tao-Wei Ke, Tsung-Wei Chen, Yu-Ching Lan, Ying-Shu You, William Tzu-Liang Chen, K. S. Clifford Chao
Can benign lymphoid tissue changes in 18F-FDG PET/CT predict response to immunotherapy in metastatic melanoma?
- Original Article
Christos Sachpekidis, Lionel Larribère, Annette Kopp-Schneider, Jessica C. Hassel, Antonia Dimitrakopoulou-Strauss
Tumor-infiltrating immune cell subpopulations and programmed death ligand 1 (PD-L1) expression associated with clinicopathological and prognostic parameters in ependymoma
- Original Article
Soo Jeong Nam, Young-Hoon Kim, Ji Eun Park, Young-shin Ra, Shin Kwang Khang, Young Hyun Cho, Jeong Hoon Kim, Chang Ohk Sung
Phase 1 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell carcinoma
- Open Access
- Clinical Trial Report
Charlotte M. Huijts, Inge M. Werter, Sinéad M. Lougheed, Ruben S. Goedegebuure, Carla M. van Herpen, Paul Hamberg, Metin Tascilar, John B. Haanen, Henk M. Verheul, Tanja D. de Gruijl, Hans J. van der Vliet
A phase I clinical study of a cocktail vaccine of Wilms’ tumor 1 (WT1) HLA class I and II peptides for recurrent malignant glioma
- Open Access
- Clinical Trial Report
Akihiro Tsuboi, Naoya Hashimoto, Fumihiro Fujiki, Soyoko Morimoto, Naoki Kagawa, Hiroko Nakajima, Naoki Hosen, Sumiyuki Nishida, Jun Nakata, Satoshi Morita, Junichi Sakamoto, Yusuke Oji, Yoshihiro Oka, Haruo Sugiyama
