Ausgabe 2/2021
Inhalt (25 Artikel)
Systemic therapy for metastatic renal cell carcinoma in the first-line setting: a systematic review and network meta-analysis
Keiichiro Mori, Hadi Mostafaei, Noriyoshi Miura, Pierre I. Karakiewicz, Stefano Luzzago, Manuela Schmidinger, Andreas Bruchbacher, Benjamin Pradere, Shin Egawa, Shahrokh F. Shariat
Identification of STXBP6-IRF1 positive feedback loop in regulation of PD-L1 in cancer
Yanbin Liu, Zhicong Huang, Yanli Wei, Mingming Zhang, Xingzhi Li, Shulan Yang, Haihe Wang
Therapeutic potential of anti-VEGF receptor 2 therapy targeting for M2-tumor-associated macrophages in colorectal cancer
Aung Kyi Thar Min, Kosaku Mimura, Shotaro Nakajima, Hirokazu Okayama, Katsuharu Saito, Wataru Sakamoto, Shotaro Fujita, Hisahito Endo, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Shinji Ohki, Koji Kono
Improved survival in patients with thyroid function test abnormalities secondary to immune-checkpoint inhibitors
Joana Lima Ferreira, Cláudia Costa, Bernardo Marques, Sofia Castro, Margarida Victor, Joana Oliveira, Ana Paula Santos, Inês Lucena Sampaio, Hugo Duarte, Ana Paula Marques, Isabel Torres
B7-H3 is spliced by SRSF3 in colorectal cancer
Chunxia Zhang, Yinshuang Chen, Fuchao Li, Man Yang, Fanyi Meng, Yawen Zhang, Weichang Chen, Weipeng Wang
Anti-PD-1 antibody increases NK cell cytotoxicity towards nasopharyngeal carcinoma cells in the context of chemotherapy-induced upregulation of PD-1 and PD-L1
Anna Makowska, Selina Meier, Lian Shen, Pierre Busson, Valentin Baloche, Udo Kontny
A high number of PD-L1+ CD14+ monocytes in peripheral blood is correlated with shorter survival in patients receiving immune checkpoint inhibitors
Kiyohiro Ando, Kazuyuki Hamada, Midori Shida, Ryotaro Ohkuma, Yutaro Kubota, Atsushi Horiike, Hiroto Matsui, Tomoyuki Ishiguro, Yuya Hirasawa, Hirotsugu Ariizumi, Makoto Watanabe, Rie Onoue, Junji Tsurutani, Kiyoshi Yoshimura, Takuya Tsunoda, Shinichi Kobayashi, Satoshi Wada
Expression pattern, regulation, and clinical significance of TOX in breast cancer
Mohit Arora, Sarita Kumari, Jay Singh, Anita Chopra, Shyam S. Chauhan
Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity
Yan Wang, Haiqing Ni, Shuaixiang Zhou, Kaijie He, Yarong Gao, Weiwei Wu, Min Wu, Zhihai Wu, Xuan Qiu, Ying Zhou, Bingliang Chen, Donghui Pan, Chenrong Huang, Mingzhu Li, Yicong Bian, Min Yang, Liyan Miao, Junjian Liu
Associations among the mutational landscape, immune microenvironment, and prognosis in Chinese patients with hepatocellular carcinoma
Zhi-Qiang Hu, Hao-Yang Xin, Chu-Bin Luo, Jia Li, Zheng-Jun Zhou, Ji-Xue Zou, Shao-Lai Zhou
Evaluation of antitumor immunity by a combination treatment of high-dose irradiation, anti-PDL1, and anti-angiogenic therapy in murine lung tumors
Jenny Ling-Yu Chen, Chun-Kai Pan, Yu-Sen Huang, Ching-Yi Tsai, Chun-Wei Wang, Yu-Li Lin, Sung-Hsin Kuo, Ming-Jium Shieh
Chemotherapy negatively impacts the tumor immune microenvironment in NSCLC: an analysis of pre- and post-treatment biopsies in the multi-center SAKK19/09 study
M. A. Amrein, E. D. Bührer, M. L. Amrein, Q. Li, S. Rothschild, C. Riether, R. Jaggi, S. Savic-Prince, L. Bubendorf, O. Gautschi, A. F. Ochsenbein
Coexpression of CMTM6 and PD-L1 as a predictor of poor prognosis in macrotrabecular-massive hepatocellular carcinoma
Li-Li Liu, Shi-Wen Zhang, Xue Chao, Chun-Hua Wang, Xia Yang, Xin-Ke Zhang, Yan-lin Wen, Jing-Ping Yun, Rong-Zhen Luo
Immunoscore is a strong predictor of survival in the prognosis of stage II/III gastric cancer patients following 5-FU-based adjuvant chemotherapy
Sumi Yun, Jiwon Koh, Soo Kyung Nam, Yoonjin Kwak, Sang-Hoon Ahn, Joong Do Park, Hyung-Ho Kim, Woo Ho Kim, Hye Seung Lee
The impact of ICOS+ regulatory T cells and Helicobacter pylori infection on the prognosis of patients with gastric and colorectal cancer: potential prognostic benefit of pre-operative eradication therapy
Shinya Urakawa, Makoto Yamasaki, Tomoki Makino, Yukinori Kurokawa, Kei Yamamoto, Kumiko Goto, Miya Haruna, Michinari Hirata, Akiko Morimoto-Okazawa, Atsunari Kawashima, Kota Iwahori, Tsunekazu Mizushima, Eiichi Sato, Masaki Mori, Yuichiro Doki, Hisashi Wada
PD-L1+ lung cancer stem cells modify the metastatic lymph-node immunomicroenvironment in nsclc patients
A. Raniszewska, H. Vroman, D. Dumoulin, R. Cornelissen, J. G. J. V. Aerts, J. Domagała-Kulawik
Tumor cell-derived autophagosomes (DRibbles)-activated B cells induce specific naïve CD8+ T cell response and exhibit antitumor effect
Tian-Yu Zhang, Hong-Yan Ren, Ning Pan, Hui-Xia Dong, Si-Min Zhao, Zhi-Fa Wen, Xu-Ru Wang, Li-Xin Wang
Dissecting the immune landscape of tumor draining lymph nodes in melanoma with high-plex spatially resolved protein detection
Georgia M. Beasley, Aaron D. Therien, Eda K. Holl, Rami Al-Rohil, Maria Angelica Selim, Nellie E. Farrow, Liuliu Pan, Premi Haynes, Yan Liang, Douglas S. Tyler, Brent A. Hanks, Smita K. Nair
Immunogenic necroptosis in the anti-tumor photodynamic action of BAM-SiPc, a silicon(IV) phthalocyanine-based photosensitizer
Ying Zhang, Ying-Kit Cheung, Dennis K. P. Ng, Wing-Ping Fong
The introduction of immunosuppressor (TDO inhibitor) significantly improved the efficacy of irinotecan in treating hepatocellular carcinoma
Qingqing Liu, Shixian Hua, Xinyi Wang, Feihong Chen, Shaohua Gou
T-cell complexity and density are associated with sensitivity to neoadjuvant chemoradiotherapy in patients with rectal cancer
Takashi Akiyoshi, Osamu Gotoh, Norio Tanaka, Kazuma Kiyotani, Noriko Yamamoto, Masashi Ueno, Yosuke Fukunaga, Seiichi Mori
Neoadjuvant chemotherapy alters the balance of effector to suppressor immune cells in advanced ovarian cancer
Alexandra Leary, Catherine Genestie, Félix Blanc-Durand, Sébastien Gouy, Ariane Dunant, Amandine Maulard, Françoise Drusch, Bianca Cheaib, Judith Michels, Enrica Bentivegna, Audrey LeFormal, Soizick Mesnage, Philippe Morice, Patricia Pautier, Aya S. Khairallah
Development of nomograms to predict therapeutic response and prognosis of non-small cell lung cancer patients treated with anti-PD-1 antibody
Shijin Yuan, Yan Xia, Lihong Shen, Liuqing Ye, Lisha Li, Lifen Chen, Xinyou Xie, Haizhou Lou, Jun Zhang
Curdlan, zymosan and a yeast-derived β-glucan reshape tumor-associated macrophages into producers of inflammatory chemo-attractants
Priscilla de Graaff, Cor Berrevoets, Christiane Rӧsch, Henk A. Schols, Kees Verhoef, Harry J. Wichers, Reno Debets, Coen Govers
Fingolimod and tumor-infiltrating lymphocytes in checkpoint-inhibitor treated cancer patients
Omar Hasan Ali, Fiamma Berner, Christoph Jakob Ackermann, Sandra Stephanie Ring, Alexandre Moulin, Joachim Müller, Eva Markert, Oltin Tiberiu Pop, Stefanie Müller, Stefan Diem, Thomas Hundsberger, Lukas Flatz