Skip to main content

Cancer Immunology, Immunotherapy

Ausgabe 3/2021

Inhalt (25 Artikel)

Open Access Review

Varied functions of immune checkpoints during cancer metastasis

Ali Safarzadeh, Mohsen Alizadeh, Fatemeh Beyranvand, Reza Falavand Jozaaee, Khalil Hajiasgharzadeh, Amir Baghbanzadeh, Afshin Derakhshani, Antonella Argentiero, Behzad Baradaran, Nicola Silvestris

Open Access Review

Toxicity with small molecule and immunotherapy combinations in non-small cell lung cancer

H. Adderley, F. H. Blackhall, C. R. Lindsay

Review

A systematic scoping review on natural killer cell function in colorectal cancer

Fiona S. W. Reid, Natasha Egoroff, Peter G. Pockney, Stephen R. Smith

Original Article

Anti-tumor and immune modulating activity of T cell induced tumor-targeting effectors (TITE)

Archana Thakur, Sri Vidya Kondadasula, Kyungmin Ji, Dana L. Schalk, Edwin Bliemeister, Johnson Ung, Amro Aboukameel, Eli Casarez, Bonnie F. Sloane, Lawrence G. Lum

Original Article

Early C-reactive protein kinetics predict survival of patients with advanced urothelial cancer treated with pembrolizumab

Toshiki Kijima, Hina Yamamoto, Kazutaka Saito, Shota Kusuhara, Soichiro Yoshida, Minato Yokoyama, Yoh Matsuoka, Noboru Numao, Yasuyuki Sakai, Nobuaki Matsubara, Takeshi Yuasa, Hitoshi Masuda, Junji Yonese, Yukio Kageyama, Yasuhisa Fujii

Original Article

Unique TP53 neoantigen and the immune microenvironment in long-term survivors of Hepatocellular carcinoma

Huayu Yang, Lejia Sun, Ai Guan, Huanhuan Yin, Meixi Liu, Xinxin Mao, Haifeng Xu, Haitao Zhao, Xin Lu, Xinting Sang, Shouxian Zhong, Qian Chen, Yilei Mao

Original Article

Increased thyroid uptake on 18F-FDG PET/CT is associated with the development of permanent hypothyroidism in stage IV melanoma patients treated with anti-PD-1 antibodies

Alexandra Frelau, Xavier Palard-Novello, Eva Jali, Lise Boussemart, Alain Dupuy, Pandora James, Anne Devillers, Florence Le Jeune, Julien Edeline, Thierry Lesimple, Antoine Girard

Original Article

Monophosphoryl lipid A-induced activation of plasmacytoid dendritic cells enhances the anti-cancer effects of anti-PD-L1 antibodies

Wei Zhang, Seong-Min Lim, Juyoung Hwang, Srinivasan Ramalingam, Myunghee Kim, Jun-O Jin

Open Access Original Article

Immune checkpoint-related serum proteins and genetic variants predict outcomes of localized prostate cancer, a cohort study

Qinchuan Wang, Yuanqing Ye, Hao Yu, Shu-Hong Lin, Huakang Tu, Dong Liang, David W. Chang, Maosheng Huang, Xifeng Wu

Original Article

Post-treatment neutrophil-to-lymphocyte ratio (NLR) predicts response to anti-PD-1/PD-L1 antibody in SCLC patients at early phase

Qi Xiong, Ziwei Huang, Lingli Xin, Boyu Qin, Xiao Zhao, Jing Zhang, Weiwei Shi, Bo Yang, Guoqing Zhang, Yi Hu

Original Article

Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma

Rosa Nguyen, Anand G. Patel, Lyra M. Griffiths, Jason Dapper, Elizabeth A. Stewart, Jim Houston, Melissa Johnson, Walter J. Akers, Wayne L. Furman, Michael A. Dyer

Original Article

Reviving up dendritic cells can run cancer immune wheel in non-small cell lung cancer: a prospective two-arm study

Asmaa M. Zahran, Helal F. Hetta, Shimaa Mansour, Ereny S. Saad, Amal Rayan

Original Article

A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC)

J. Chandra, W. P. Woo, N. Finlayson, H. Y. Liu, M. McGrath, R. Ladwa, M. Brauer, Y. Xu, S. Hanson, B. Panizza, I. H. Frazer, Sandro V. Porceddu

Open Access Original Article

Phase I, first-in-human trial of programmed cell death receptor-1 (PD-1) inhibitor, JTX-4014, in adult patients with advanced, refractory, solid tumors

Kyriakos P. Papadopoulos, Nehal Lakhani, Gerald S. Falchook, Gosia Riley, Johan Baeck, Karen S. Brown, Gilad Gordon, Lidya Le, Judy S. Wang

Open Access Original Article

Differential gene expression of tumor-infiltrating CD33+ myeloid cells in advanced- versus early-stage colorectal cancer

Salman M. Toor, Rowaida Z. Taha, Varun Sasidharan Nair, Reem Saleh, Khaled Murshed, Mohamed Abu Nada, Eyad Elkord

Original Article

Downregulated ATP6V1B1 expression acidifies the intracellular environment of cancer cells leading to resistance to antibody-dependent cellular cytotoxicity

Mariko Nishie, Eiji Suzuki, Masakazu Hattori, Kosuke Kawaguch, Tatsuki R. Kataoka, Masahiro Hirata, Fengling Pu, Takeshi Kotake, Moe Tsuda, Ayane Yamaguchi, Tomoharu Sugie, Masakazu Toi

Original Article

High tumor mutational burden and T-cell activation are associated with long-term response to anti-PD1 therapy in Lynch syndrome recurrent glioblastoma patient

Elena Anghileri, Natalia Di Ianni, Rosina Paterra, Tiziana Langella, Junfei Zhao, Marica Eoli, Monica Patanè, Bianca Pollo, Valeria Cuccarini, Antonio Iavarone, Raul Rabadan, Gaetano Finocchiaro, Serena Pellegatta

Original Article

PD-1/PD-L1 checkpoint inhibitors in combination with olaparib display antitumor activity in ovarian cancer patient-derived three-dimensional spheroid cultures

Kathryn M. Appleton, Ashley K. Elrod, Katy A. Lassahn, Stephen Shuford, Lillia M. Holmes, Teresa M. DesRochers

Open Access Clinical Trial Report

Efficacy and safety of sintilimab in combination with chemotherapy in previously untreated advanced or metastatic nonsquamous or squamous NSCLC: two cohorts of an open-label, phase 1b study

Haiping Jiang, Yulong Zheng, Jiong Qian, Chenyu Mao, Xin Xu, Ning Li, Cheng Xiao, Huan Wang, Lisong Teng, Hui Zhou, Shuyan Wang, Donglei Zhu, Tao Sun, Yingying Yu, Wenying Guo, Nong Xu

Research Report

Patterns of immune checkpoint protein expression in MYC-overexpressing aggressive B-cell non-Hodgkin lymphomas

Daniel J. Landsburg, Alexa Koike, Sunita D. Nasta, Jakub Svoboda, Stephen J. Schuster, Mariusz A. Wasik, Gabriel C. Caponetti

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.