Ausgabe 4/2020
Inhalt (15 Artikel)
CD16 pre-ligation by defucosylated tumor-targeting mAb sensitizes human NK cells to γc cytokine stimulation via PI3K/mTOR axis
- Open Access
- Original Article
Cristina Capuano, Chiara Pighi, Roberta Maggio, Simone Battella, Stefania Morrone, Gabriella Palmieri, Angela Santoni, Christian Klein, Ricciarda Galandrini
High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma
- Open Access
- Original Article
Jeroen Melief, Yago Pico de Coaña, Roeltje Maas, Felix-Lennart Fennemann, Maria Wolodarski, Johan Hansson, Rolf Kiessling
Immune profile and immunosurveillance in treatment-naive and neoadjuvantly treated esophageal adenocarcinoma
- Open Access
- Original Article
Svenja Wagener-Ryczek, Max Schoemmel, Max Kraemer, Christiane Bruns, Wolfgang Schroeder, Thomas Zander, Florian Gebauer, Hakan Alakus, Sabine Merkelbach-Bruse, Reinhard Buettner, Heike Loeser, Martin Thelen, Hans A. Schlößer, Alexander Quaas
Enhanced glucose metabolism mediated by CD147 contributes to immunosuppression in hepatocellular carcinoma
- Original Article
Xiaofeng Li, Yufan Zhang, Wenchao Ma, Qiang Fu, Jianjing Liu, Guotao Yin, Peihe Chen, Dong Dai, Wei Chen, Lisha Qi, Xiaozhou Yu, Wengui Xu
The expression and prognostic impact of proinflammatory cytokines and their associations with carcinogens in oropharyngeal squamous cell carcinoma
- Original Article
Chi-Maw Lin, Long-Wei Lin, Ya-Wen Chen, Yi-Ling Ye
The neutrophil–lymphocyte ratio and locoregional melanoma: a multicentre cohort study
- Open Access
- Original Article
Alyss V. Robinson, Claire Keeble, Michelle C. I. Lo, Owen Thornton, Howard Peach, Marc D. S. Moncrieff, Donald J. Dewar, Ryckie G. Wade
Treatment with an immature dendritic cell-targeting vaccine supplemented with IFN-α and an inhibitor of DNA methylation markedly enhances survival in a murine melanoma model
- Original Article
James T. Gordy, Kun Luo, Aakanksha Kapoor, Emily S. Kim, Samuel K. Ayeh, Petros C. Karakousis, Richard B. Markham
Digital pathology-aided assessment of tumor-infiltrating T lymphocytes in advanced stage, HPV-negative head and neck tumors
- Open Access
- Original Article
Emma J. de Ruiter, Reinout H. de Roest, Ruud H. Brakenhoff, C. René Leemans, Remco de Bree, Chris H. J. Terhaard, Stefan M. Willems
Suppressive activity of Vδ2+ γδ T cells on αβ T cells is licensed by TCR signaling and correlates with signal strength
- Open Access
- Original Article
Karin Schilbach, Naomi Krickeberg, Carlotta Kaißer, Simon Mingram, Janika Kind, Gabrielle M. Siegers, Hisayoshi Hashimoto
PKCζ mediated anti-proliferative effect of C2 ceramide on neutralization of the tumor microenvironment and melanoma regression
- Original Article
Sweta Ghosh, Subir Kumar Juin, Partha Nandi, Suchandra Bhattacharyya Majumdar, Anamika Bose, Rathindranath Baral, Parames C. Sil, Subrata Majumdar
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition
- Original Article
Jochen Greiner, Marlies Götz, Susanne Hofmann, Hubert Schrezenmeier, Markus Wiesneth, Lars Bullinger, Hartmut Döhner, Vanessa Schneider
Bovine papillomavirus prostate cancer antigen virus-like particle vaccines are efficacious in advanced cancers in the TRAMP mouse spontaneous prostate cancer model
- Original Article
Brian W. Simons, Fabiana Cannella, Dayana T. Rowley, Raphael P. Viscidi
Response to ipilimumab therapy in metastatic melanoma patients: potential relevance of CTLA-4+ tumor infiltrating lymphocytes and their in situ localization
- Original Article
Luca Mastracci, Vincenzo Fontana, Paola Queirolo, Roberta Carosio, Federica Grillo, Anna Morabito, Barbara Banelli, Enrica Tanda, Andrea Boutros, Beatrice Dozin, Marina Gualco, Sandra Salvi, Massimo Romani, Francesco Spagnolo, Alessandro Poggi, Maria Pia Pistillo
First-in-human phase I clinical trial of the NY-ESO-1 protein cancer vaccine with NOD2 and TLR9 stimulants in patients with NY-ESO-1-expressing refractory solid tumors
- Open Access
- Clinical Trial Report
Mikiya Ishihara, Yasutaka Tono, Yoshihiro Miyahara, Daisuke Muraoka, Naozumi Harada, Shinichi Kageyama, Takeshi Sasaki, Yasuhide Hori, Norihito Soga, Katsunori Uchida, Taizo Shiraishi, Eiichi Sato, Hideki Kanda, Toshiro Mizuno, Gill A. Webster, Hiroaki Ikeda, Naoyuki Katayama, Yoshiki Sugimura, Hiroshi Shiku
International Regensburg Center for Interventional Immunology (RCI) symposium on “Synthetic immunology and environment-adapted redirection of T cells”, 17–18 July, 2019, Regensburg, Germany
- Open Access
- Meeting Report
Philipp Beckhove, Matthias Edinger, Markus Feuerer, Luca Gattinoni, Hinrich Abken
