Ausgabe 4/2022
Inhalt (22 Artikel)
Immunotherapy for gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs): a 2021 update
- Review
Christo Kole, Nikolaos Charalampakis, Michail Vailas, Maria Tolia, Maria Sotiropoulou, Sergios Tsakatikas, Nikolaos-Iasonas Kouris, Marina Tsoli, Anna Koumarianou, Michalis V. Karamouzis, Dimitrios Schizas
Neurological disorders associated with immune checkpoint inhibitors: an association with autoantibodies
- Review
Morinobu Seki, Shigehisa Kitano, Shigeaki Suzuki
Dynamic switch of immunity and antitumor effects of metformin in rat spontaneous esophageal carcinogenesis
- Open Access
- Original Article
Ryohei Takei, Tomoharu Miyashita, Satoshi Takada, Hidehiro Tajima, Itasu Ninomiya, Hiroyuki Takamura, Sachio Fushida, Ai Harashima, Seiichi Munesue, Shintaro Yagi, Noriyuki Inaki, Tetsuo Ohta, Yasuhiko Yamamoto
Correction to: Dynamic switch of immunity and antitumor effects of metformin in rat spontaneous esophageal carcinogenesis
- Open Access
- Correction
Ryohei Takei, Tomoharu Miyashita, Satoshi Takada, Hidehiro Tajima, Itasu Ninomiya, Hiroyuki Takamura, Sachio Fushida, Ai Harashima, Seiichi Munesue, Shintaro Yagi, Noriyuki Inaki, Tetsuo Ohta, Yasuhiko Yamamoto
GRIK2 is a target for bladder cancer stem-like cell-targeting immunotherapy
- Original Article
Haruka Miyata, Yoshihiko Hirohashi, Shuhei Yamada, Junko Yanagawa, Aiko Murai, Shinichi Hashimoto, Serina Tokita, Kanta Hori, Takashige Abe, Terufumi Kubo, Tomohide Tsukahara, Takayuki Kanaseki, Nobuo Shinohara, Toshihiko Torigoe
Increased tumor-infiltrating lymphocyte density is associated with favorable outcomes in a comparative study of canine histiocytic sarcoma
- Original Article
Jennifer A. Lenz, Charles-Antoine Assenmacher, Victoria Costa, Katie Louka, Suzanne Rau, Nicholas S. Keuler, Paul J. Zhang, Robert G. Maki, Amy C. Durham, Enrico Radaelli, Matthew J. Atherton
No evidence that HLA genotype influences the driver mutations that occur in cancer patients
- Open Access
- Original Article
Noor Kherreh, Siobhán Cleary, Cathal Seoighe
Prognostic value of natural killer cell activity for patients with HER2 + advanced gastric cancer treated with first-line fluoropyrimidine–platinum doublet plus trastuzumab
- Original Article
Hyungwoo Cho, Min-Hee Ryu, Hyung Eun Lee, Hyung-Don Kim, Yoon-Koo Kang
Long-term expression changes of immune-related genes in prostate cancer after radiotherapy
- Original Article
Iris Eke, Molykutty J. Aryankalayil, Michelle A. Bylicky, Veit Sandfort, Claire Vanpouille-Box, Saravanan Nandagopal, Edward E. Graves, Amato J. Giaccia, C. Norman Coleman
Dynamic alterations of circulating T lymphocytes and the clinical response in patients with head and neck squamous cell carcinoma treated with nivolumab
- Original Article
Hiroe Tada, Hideyuki Takahashi, Kanae Yamada, Kei Masuda, Yurino Nagata, Miho Uchida, Masato Shino, Shota Ida, Ikko Mito, Toshiyuki Matsuyama, Tetsunari Oyama, Ken-Ichiro Tatematsu, Hideki Sezutsu, Shigeki Takeda, Kazuaki Chikamatsu
Clinical outcomes of NSCLC patients experiencing early immune-related adverse events to PD-1/PD-L1 checkpoint inhibitors leading to treatment discontinuation
- Original Article
Marco Russano, Alessio Cortellini, Raffaele Giusti, Alessandro Russo, Federica Zoratto, Francesca Rastelli, Alain Gelibter, Rita Chiari, Olga Nigro, Michele De Tursi, Sergio Bracarda, Stefania Gori, Francesco Grossi, Melissa Bersanelli, Lorenzo Calvetti, Vincenzo Di Noia, Mario Scartozzi, Massimo Di Maio, Paolo Bossi, Alfredo Falcone, Fabrizio Citarella, Francesco Pantano, Corrado Ficorella, Marco Filetti, Vincenzo Adamo, Enzo Veltri, Federica Pergolesi, Mario Alberto Occhipinti, Linda Nicolardi, Alessandro Tuzi, Pietro Di Marino, Serena Macrini, Alessandro Inno, Michele Ghidini, Sebastiano Buti, Giuseppe Aprile, Eleonora Lai, Marco Audisio, Salvatore Intagliata, Riccardo Marconcini, Davide Brocco, Giampiero Porzio, Marta Piras, Erika Rijavec, Francesca Simionato, Clara Natoli, Marcello Tiseo, Bruno Vincenzi, Giuseppe Tonini, Daniele Santini
MAIT cells numbers and frequencies in patients with acute myeloid leukemia at diagnosis: association with cytogenetic profile and gene mutations
- Original Article
Thibault Comont, Marie-Laure Nicolau-Travers, Sarah Bertoli, Christian Recher, Francois Vergez, Emmanuel Treiner
Combination therapy for hepatocellular carcinoma with diacylglycerol kinase alpha inhibition and anti-programmed cell death-1 ligand blockade
- Original Article
Naoki Okada, Ko Sugiyama, Shunsuke Shichi, Yasuhito Shirai, Kaoru Goto, Fumio Sakane, Hidemitsu Kitamura, Akinobu Taketomi
Tumor-infiltrating CD8+ T cells recognize a heterogeneously expressed functional neoantigen in clear cell renal cell carcinoma
- Original Article
Masahiro Matsuki, Yoshihiko Hirohashi, Munehide Nakatsugawa, Aiko Murai, Terufumi Kubo, Shinichi Hashimoto, Serina Tokita, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Sachiyo Nishida, Toshiaki Tanaka, Hiroshi Kitamura, Naoya Masumori, Toshihiko Torigoe
The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides
- Original Article
Oleg Kruglov, Lisa D. S. Johnson, Angela Minic, Kimberly Jordan, Robert A. Uger, Mark Wong, Eric L. Sievers, Yaping Shou, Oleg E. Akilov
Immune cell profiles in the tumor microenvironment of early-onset, intermediate-onset, and later-onset colorectal cancer
- Original Article
Tomotaka Ugai, Juha P. Väyrynen, Mai Chan Lau, Jennifer Borowsky, Naohiko Akimoto, Sara A. Väyrynen, Melissa Zhao, Rong Zhong, Koichiro Haruki, Andressa Dias Costa, Kenji Fujiyoshi, Kota Arima, Kana Wu, Andrew T. Chan, Yin Cao, Mingyang Song, Charles S. Fuchs, Molin Wang, Jochen K. Lennerz, Kimmie Ng, Jeffrey A. Meyerhardt, Marios Giannakis, Jonathan A. Nowak, Shuji Ogino
Association between pathogenic germline mutations in BRCA2 and ATM and tumor-infiltrating lymphocytes in primary prostate cancer
- Original Article
Harsimar B. Kaur, Thiago Vidotto, Adrianna A. Mendes, Daniela C. Salles, William B. Isaacs, Emmanuel S. Antonarakis, Tamara L. Lotan
Tumor microenvironment is associated with clinical and genetic properties of diffuse gliomas and predicts overall survival
- Original Article
Qiang-Wei Wang, Zhao-Shi Bao, Tao Jiang, Yong-Jian Zhu
Combined treatment with anti-HER2/neu and anti-4-1BB monoclonal antibodies induces a synergistic antitumor effect but requires dose optimization to maintain immune memory for protection from lethal rechallenge
- Original Article
Hee Yeon Kim, Jae-Hyeog Choi, Md. Masudul Haque, Jin Hee Park, Il-Hwan Kim, Beom K. Choi, Anbok Lee, SaeGwang Park
Venetoclax-resistant CLL cells show a highly activated and proliferative phenotype
- Research Report
Esteban Enrique Elias, Valeria Judith Sarapura Martinez, Mikele Amondarain, Ana Colado, Gregorio Cordini, Raimundo Fernando Bezares, Horacio Fernandez Grecco, Maria del Rosario Custidiano, Julio César Sánchez Ávalos, Gonzalo Garate, Miguel A. Pavlovsky, Mercedes Borge, Mirta Giordano, Romina Gamberale
Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures
- Research Report
Yvonne H. F. Teng, Hong Sheng Quah, Lisda Suteja, João M. L. Dias, Annalisa Mupo, Rachael J. M. Bashford-Rogers, George S. Vassiliou, Melvin L. K. Chua, Daniel S. W. Tan, Darren W. T. Lim, N. Gopalakrishna Iyer
Correction to: Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures
- Correction
Yvonne H. F. Teng, Hong Sheng Quah, Lisda Suteja, João M. L. Dias, Annalisa Mupo, Rachael J. M. Bashford-Rogers, George S. Vassiliou, Melvin L. K. Chua, Daniel S. W. Tan, Darren W. T. Lim, N. Gopalakrishna Iyer
