Ausgabe 4/2023
Inhalt (22 Artikel)
Inhibitory receptors for HLA class I as immune checkpoints for natural killer cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy
- Open Access
- Review
Nicky A. Beelen, Femke A. I. Ehlers, Gerard M. J. Bos, Lotte Wieten
Lymphodepleting chemotherapy practices and effect on safety and efficacy outcomes in patients with solid tumours undergoing T cell receptor-engineered T cell (TCR-T) Therapy: a systematic review and meta-analysis
- Open Access
- Review
Kathryn Owen, Ramy Ghaly, Kyrillus S. Shohdy, Fiona Thistlethwaite
Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities
- Research
Zhen Lu, Eun-Ah Bae, Ioannis I. Verginadis, Hongru Zhang, Christina Cho, Noreen McBrearty, Subin S. George, J. Alan Diehl, Constantinos Koumenis, Linda M. Bradley, Serge Y. Fuchs
A Phase I-II multicenter trial with Avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients; GEMCAD 1602 study
- Open Access
- Research
Marta Español-Rego, Carlos Fernández-Martos, Elena Elez, Carles Foguet, Leire Pedrosa, Nuria Rodríguez, Ana Ruiz-Casado, Estela Pineda, Joan Cid, Raquel Cabezón, Helena Oliveres, Miquel Lozano, Angels Ginés, Angeles García-Criado, Juan Ramon Ayuso, Mario Pagés, Miriam Cuatrecasas, Ferràn Torres, Timothy Thomson, Marta Cascante, Daniel Benítez-Ribas, Joan Maurel
Effectiveness of pembrolizumab in trial-ineligible patients with metastatic urothelial carcinoma
- Research
Wataru Fukuokaya, Takafumi Yanagisawa, Masaki Hashimoto, Shutaro Yamamoto, Yuhei Koike, Yu Imai, Kosuke Iwatani, Hajime Onuma, Kagenori Ito, Fumihiko Urabe, Shunsuke Tsuzuki, Shoji Kimura, Jun Miki, Yu Oyama, Hirokazu Abe, Takahiro Kimura
Tumor-derived interleukin-34 creates an immunosuppressive and chemoresistant tumor microenvironment by modulating myeloid-derived suppressor cells in triple-negative breast cancer
- Research
Nabeel Kajihara, Takuto Kobayashi, Ryo Otsuka, Junko Nio-Kobayashi, Tomohiro Oshino, Masato Takahashi, Seiichi Imanishi, Ari Hashimoto, Haruka Wada, Ken-ichiro Seino
Effects of tumor-infiltrating CD8+ T cells, PD1/PD-L1 axis, and expression patterns of HLA class I on the prognosis of patients with malignant pleural mesothelioma who underwent extra-pleural pneumonectomy
- Research
Riki Okita, Yuka Mimura-Kimura, Nobutaka Kawamoto, Naoki Yamamoto, Masashi Umeda, Masanori Okada, Hidetoshi Inokawa, Yusuke Mimura, Tomoyuki Murakami, Masao Nakata, Kazunori Okabe
PLEK2 and IFI6, representing mesenchymal and immune-suppressive microenvironment, predicts resistance to neoadjuvant immunotherapy in esophageal squamous cell carcinoma
- Research
Jianhua Liu, Hao Chen, Guibin Qiao, Jia-Tao Zhang, Shuaitong Zhang, Changbin Zhu, Yu Chen, Jiming Tang, Weiwei Li, Siyun Wang, Hongxia Tian, Zhihong Chen, Dong Ma, Jie Tian, Yi-Long Wu
Pancreatic involvement due to immune checkpoint inhibitors: a proposed classification
- Research
Motaz Ashkar, Shruti Chandra, Santhi Swaroop Vege, Hiroaki Takahashi, Naoki Takahashi, Robert R. McWilliams
ZIM3 activation of CCL25 expression in pulmonary metastatic nodules of osteosarcoma recruits M2 macrophages to promote metastatic growth
- Research
Jing Li, Chenguang Zhao, Dong Wang, Shuang Wang, Hui Dong, Difan Wang, Yubing Yang, Jiaxi Li, Feng Cui, Xijing He, Jie Qin
Dominant-negative transforming growth factor-β receptor-armoured mesothelin-targeted chimeric antigen receptor T cells slow tumour growth in a mouse model of ovarian cancer
- Open Access
- Research
Ke Li, Jing Xu, Jing Wang, Chong Lu, Yilin Dai, Qing Dai, Wang Zhang, Congjian Xu, Shu Wu, Yu Kang
Live attenuated VZV vaccination induces antitumor immunity in ATLL patients
- Open Access
- Research
Tatsuro Jo, Ritsuko Kubota-Koketsu, Yohei Kaneko, Takahiro Sakai, Kazuhiro Noguchi, Sadaharu Irie, Masatoshi Matsuo, Jun Taguchi, Kuniko Abe, Kazuto Shigematsu
Nivolumab versus placebo as adjuvant therapy for resected stage III melanoma: a propensity weighted indirect treatment comparison and number needed to treat analysis for recurrence-free survival and overall survival
- Open Access
- Research
Jeffrey S. Weber, Tayla Poretta, Brian D. Stwalley, Leon A. Sakkal, Ella X. Du, Travis Wang, Yan Chen, Yan Wang, Keith A. Betts, Alexander N. Shoushtari
Correction to: Nivolumab versus placebo as adjuvant therapy for resected stage III melanoma: a propensity weighted indirect treatment comparison and number needed to treat analysis for recurrence-free survival and overall survival
- Open Access
- Correction
Jeffrey S. Weber, Tayla Poretta, Brian D. Stwalley, Leon A. Sakkal, Ella X. Du, Travis Wang, Yan Chen, Yan Wang, Keith A. Betts, Alexander N. Shoushtari
Targeting FLT3-specific chimeric antigen receptor T cells for acute lymphoblastic leukemia with KMT2A rearrangement
- Research
Masaya Suematsu, Shigeki Yagyu, Hideki Yoshida, Shinya Osone, Yozo Nakazawa, Kanji Sugita, Toshihiko Imamura, Tomoko Iehara
αVEGFR2-MICA fusion antibodies enhance immunotherapy effect and synergize with PD-1 blockade
- Research
Mingzhu Pan, Fei Wang, Lidi Nan, Siyu Yang, Jinyao Qi, Jiajun Xie, Shuai Shao, Hongyi zou, Min Wang, Fumou Sun, Juan Zhang
Peptide vaccine from cancer-testis antigen ODF2 can potentiate the cytotoxic T lymphocyte infiltration through IL-15 in non-MSI-H colorectal cancer
- Research
Ranran Shi, Xiuman Zhou, Liwei Pang, Mingshuang Wang, Yubing Li, Chunxia Chen, Haoming Ning, Lihan Zhang, Guangxing Yue, Lu Qiu, Wenshan Zhao, Yuanming Qi, Yahong Wu, Yanfeng Gao
PD-L1 expression on immune cells, but not on tumor cells, is a favorable prognostic factor for patients with intrahepatic cholangiocarcinoma
- Research
Lavinia Patricia Mocan, Rares Craciun, Cristiana Grapa, Carmen Stanca Melincovici, Ioana Rusu, Nadim Al Hajjar, Zeno Sparchez, Daniel Leucuta, Maria Ilies, Mihaela Sparchez, Tudor Mocan, Carmen Mihaela Mihu
Taurine enhances the antitumor efficacy of PD-1 antibody by boosting CD8+ T cell function
- Research
Yu Ping, Jiqi Shan, Yaqing Liu, Fengsen Liu, Liuya Wang, Zhangnan Liu, Jieyao Li, Dongli Yue, Liping Wang, Xinfeng Chen, Yi Zhang
Comprehensive analysis of the immunological implication and prognostic value of CXCR4 in non-small cell lung cancer
- Open Access
- Research
Wei Guo, Qilin Huai, Bolun Zhou, Lei Guo, Li Sun, Xuemin Xue, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He
Anti-PD-1 antibody-activated Th17 cells subvert re-invigoration of antitumor cytotoxic T-lymphocytes via myeloid cell-derived COX-2/PGE2
- Brief Report
Qingsheng Li, Kevin E. Goggin, SeonYeong Seo, Jonathan M. Warawa, Nejat K. Egilmez
Correction to: Anti‑PD‑1 antibody‑activated Th17 cells subvert re‑invigoration of antitumor cytotoxic T‑lymphocytes via myeloid cell‑derived COX‑2/PGE2
- Correction
Qingsheng Li, Kevin E. Goggin, SeonYeong Seo, Jonathan M. Warawa, Nejat K. Egilmez
