Ausgabe 5/2023
Inhalt (23 Artikel)
Pre-treatment soluble PD-L1 as a predictor of overall survival for immune checkpoint inhibitor therapy: a systematic review and meta-analysis
- Open Access
- Review
Ádám Széles, Tamás Fazekas, Szilard Váncsa, Melinda Váradi, Petra Terézia Kovács, Ulrich Krafft, Viktor Grünwald, Boris Hadaschik, Anita Csizmarik, Péter Hegyi, Alex Váradi, Péter Nyirády, Tibor Szarvas
Local immunotherapy with the RNA-based immune stimulator CV8102 induces substantial anti-tumor responses and enhances checkpoint inhibitor activity
- Open Access
- Research
Johannes Lutz, Michael Meister, Mohamed Habbeddine, Katja Fiedler, Aleksandra Kowalczyk, Regina Heidenreich
Inhibition of the CCR6-CCL20 axis prevents regulatory T cell recruitment and sensitizes head and neck squamous cell carcinoma to radiation therapy
- Research
Cleopatra Rutihinda, Ryma Haroun, Nour Elhouda Saidi, Juan Pablo Ordoñez, Sahar Naasri, Dominique Lévesque, François-Michel Boisvert, Pierre-Hugues Fortier, Mathieu Belzile, Laurent Fradet, Vincent Hubert-Tremblay, Guy Anne Turgeon, Chang Shu Wang, Patrick Delage, Étienne Rousseau, Benoît Paquette, Ayman J. Oweida
Immunotherapy for lung cancer combining the oligodeoxynucleotides of TLR9 agonist and TGF-β2 inhibitor
- Research
Yunpeng Yao, Jianhua Li, Kuo Qu, Yangeng Wang, Zhe Wang, Wenting Lu, Yongli Yu, Liying Wang
Transcriptomic characterization and construction of M2 macrophage-related prognostic and immunotherapeutic signature in ovarian metastasis of gastric cancer
- Research
Jianpeng Gao, Zhenxiong Zhao, Hena Zhang, Shenglin Huang, Midie Xu, Hongda Pan
Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells
- Open Access
- Research
Alistair L. J. Symonds, Tizong Miao, Zabreen Busharat, Suling Li, Ping Wang
Generation of NK cells with chimeric-switch receptors to overcome PD1-mediated inhibition in cancer immunotherapy
- Open Access
- Research
Katharina H. Susek, Ysabel A. Schwietzer, Maria Karvouni, Mari Gilljam, Marton Keszei, Alamdar Hussain, Johan Lund, Muhammad Kashif, Andreas Lundqvist, Hans-Gustaf Ljunggren, Hareth Nahi, Arnika K. Wagner, Evren Alici
Combined pembrolizumab and bevacizumab therapy effectively inhibits non-small-cell lung cancer growth and prevents postoperative recurrence and metastasis in humanized mouse model
- Open Access
- Research
Tianyun Qiao, Jinbo Zhao, Xiangbing Xin, Yanlu Xiong, Wenwen Guo, Fancheng Meng, Hui Li, Yangbo Feng, Hui Xu, Changhong Shi, Yong Han
Correction to: Combined pembrolizumab and bevacizumab therapy effectively inhibits non-small-cell lung cancer growth and prevents postoperative recurrence and metastasis in humanized mouse model
- Open Access
- Correction
Tianyun Qiao, Jinbo Zhao, Xiangbing Xin, Yanlu Xiong, Wenwen Guo, Fancheng Meng, Hui Li, Yangbo Feng, Hui Xu, Changhong Shi, Yong Han
Novel ocular immunotherapy induces tumor regression in an equine model of ocular surface squamous neoplasia
- Research
Kathryn L. Wotman, Lyndah Chow, Brittany Martabano, Lynn M. Pezzanite, Steven Dow
Somatic ARID1A mutation stratifies patients with gastric cancer to PD-1 blockade and adjuvant chemotherapy
- Open Access
- Research
Yun Gu, Puran Zhang, Jieti Wang, Chao Lin, Hao Liu, He Li, Hongyong He, Ruochen Li, Heng Zhang, Weijuan Zhang
Expansions of tumor-reactive Vdelta1 gamma-delta T cells in newly diagnosed patients with chronic myeloid leukemia
- Open Access
- Research
Andrea Knight, Martin Piskacek, Michal Jurajda, Jirina Prochazkova, Zdenek Racil, Daniela Zackova, Jiri Mayer
Nonlinear association between body mass index and overall survival in advanced NSCLC patients treated with immune checkpoint blockade
- Research
Aditya Jain, Shijia Zhang, Ryan M. Shanley, Naomi Fujioka, Robert A. Kratzke, Manish R. Patel, Amit A. Kulkarni
Expanded natural killer cells potentiate the antimyeloma activity of daratumumab, lenalidomide, and dexamethasone in a myeloma xenograft model
- Open Access
- Research
Jaya Lakshmi Thangaraj, Sung-Hoon Jung, Manh-Cuong Vo, Tan-Huy Chu, Minh-Trang Thi Phan, Kyung-Hwa Lee, Seo-Yeon Ahn, Mihee Kim, Ga-Young Song, Jae-Sook Ahn, Deok-Hwan Yang, Hyeoung-Joon Kim, Duck Cho, Je-Jung Lee
Improved MAIT cell functions following fecal microbiota transplantation for metastatic renal cell carcinoma
- Research
Marina Ninkov, Crystal L. Schmerk, Manoosh Moradizadeh, Seema N. Parvathy, Rene Figueredo, Jeremy P. Burton, Michael S. Silverman, Ricardo Fernandes, Saman Maleki Vareki, S. M. Mansour Haeryfar
Identification of TCR rearrangements specific for genetic alterations in EGFR-mutated non-small cell lung cancer: results from the ADJUVANT-CTONG1104 trial
- Research
Cunte Chen, Siyang Maggie Liu, Yedan Chen, Qiuxiang Ou, Hua Bao, Ling Xu, Yikai Zhang, Jia-Tao Zhang, Wenzhao Zhong, Qing Zhou, Xue-Ning Yang, Yang Shao, Yi-Long Wu, Si-Yang Liu, Yangqiu Li
Senescence-associated secretory proteins induced in lung adenocarcinoma by extended treatment with dexamethasone enhance migration and activation of lymphocytes
- Research
Prahlad Parajuli, Rayna Rosati, Hirva Mamdani, Robert E. Wright III, Zahin Hussain, Aroma Naeem, Sijana Dzinic, Lisa Polin, Navnath S. Gavande, Manohar Ratnam
Oncolytic virus-mediated reducing of myeloid-derived suppressor cells enhances the efficacy of PD-L1 blockade in gemcitabine-resistant pancreatic cancer
- Research
Yoshinori Kajiwara, Hiroshi Tazawa, Motohiko Yamada, Nobuhiko Kanaya, Takuro Fushimi, Satoru Kikuchi, Shinji Kuroda, Toshiaki Ohara, Kazuhiro Noma, Ryuichi Yoshida, Yuzo Umeda, Yasuo Urata, Shunsuke Kagawa, Toshiyoshi Fujiwara
Expansion of KRAS hotspot mutations reactive T cells from human pancreatic tumors using autologous T cells as the antigen-presenting cells
- Research
Sizhen Wang, Xiaohui Zhang, Xuemei Zou, Maorong Wen, Chi Gan, Xiaochun Jiang, Min Li, Rongxi Shen, Daojun Zhu, Anlong Yao, Yu Fang, Bernard A. Fox, Hong-Ming Hu, Guangjie Yu, Xinbo Wang
STAT3 promotes differentiation of monocytes to MDSCs via CD39/CD73-adenosine signal pathway in oral squamous cell carcinoma
- Research
Hao Cui, Zhou Lan, Ke-long Zou, Yu-Yue Zhao, Guang-Tao Yu
Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity
- Open Access
- Brief Report
Jennie C. Kim, Xian Liu, Karen Fitzgerald, Jason S. Eng, Jessica Orf, Sarah A. O’Brien, Brian Belmontes, Amy-Jo Casbon, Sergey V. Novitskiy, Kristin V. Tarbell, Jason DeVoss, Jackson G. Egen
Correction to: Let‑7d inhibits intratumoral macrophage M2 polarization and subsequent tumor angiogenesis by targeting IL‑13 and IL‑10
- Correction
Boxing Su, Haibo Han, Yanqing Gong, Xuesong Li, Chaoyue Ji, Jingjing Yao, Jianghui Yang, Weiguo Hu, Wei Zhao, Jianxing Li, Gang Zhang, Liqun Zhou
Correction to: TIGIT blockade enhances tumor response to radiotherapy via a CD103 + dendritic cell-dependent mechanism
- Open Access
- Correction
Kaikai Zhao, Liyang Jiang, Youjiao Si, Shujie Zhou, Zhaoqin Huang, Xiangjiao Meng
