Ausgabe 6/2024
Inhalt (20 Artikel)
CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival
- Open Access
- Research
Jessica Wedig, Shrina Jasani, Debasmita Mukherjee, Hannah Lathrop, Priya Matreja, Timothy Pfau, Liliana D’Alesio, Abigail Guenther, Lexie Fenn, Morgan Kaiser, Molly A. Torok, Jake McGue, Gina M. Sizemore, Anne M. Noonan, Mary E. Dillhoff, Bradley W. Blaser, Timothy L. Frankel, Stacey Culp, Phil A. Hart, Zobeida Cruz-Monserrate, Thomas A. Mace
Integrating bulk and single-cell sequencing data to construct a Scissor+ dendritic cells prognostic model for predicting prognosis and immune responses in ESCC
- Open Access
- Research
Maosheng Cheng, Jianqi Xiong, Qianwen Liu, Caihua Zhang, Kang Li, Xinyuan Wang, Shuang Chen
Incorporating IL7 receptor alpha signaling in the endodomain of B7H3-targeting chimeric antigen receptor T cells mediates antitumor activity in glioblastoma
- Open Access
- Research
Nithidol Sakunrangsit, Nattarika Khuisangeam, Thananya Inthanachai, Varalee Yodsurang, Pasrawin Taechawattananant, Koramit Suppipat, Supannikar Tawinwung
T-cell subsets and cytokines are indicative of neoadjuvant chemoimmunotherapy responses in NSCLC
- Open Access
- Research
Ling Yi, Ziwei Xu, Tianyu Ma, Chong Wang, Panjian Wei, Bo Xiao, Hongtao Zhang, Nanying Che, Zhidong Liu, Yi Han
Comparative performance of scFv-based anti-BCMA CAR formats for improved T cell therapy in multiple myeloma
- Open Access
- Research
Sophia Stock, Luisa Fertig, Adrian Gottschlich, Janina Dörr, Florian Märkl, Lina Majed, Vivien D. Menkhoff, Ruth Grünmeier, Kai Rejeski, David M. Cordas dos Santos, Sebastian Theurich, Michael von Bergwelt-Baildon, Stefan Endres, Marion Subklewe, Sebastian Kobold
Expansion of tumor-infiltrating lymphocytes from head and neck squamous cell carcinoma to assess the potential of adoptive cell therapy
- Open Access
- Research
Sangjoon Choi, Mofazzal Hossain, Hyun Lee, Jina Baek, Hye Seon Park, Chae-Lyul Lim, DoYeon Han, Taehyun Park, Jong Hyeok Kim, Gyungyub Gong, Mi-Na Kweon, Hee Jin Lee
TLR5 agonist in combination with anti-PD-1 treatment enhances anti-tumor effect through M1/M2 macrophage polarization shift and CD8+ T cell priming
- Open Access
- Research
Junseok Lee, Keon-Il Im, Sojin Gil, Hyemin Na, Gi-June Min, Nayoun Kim, Seok-Goo Cho
Intratumor injection of BCG Ag85A high-affinity peptides enhanced anti-tumor efficacy in PPD-positive melanoma
- Open Access
- Research
Lanqun Qin, Guiying Zhang, Yirong Wu, Yueling Yang, Zhengyun Zou
Associations of granulocyte colony-stimulating factor with toxicities and efficacy of chimeric antigen receptor T-cell therapy in relapsed or refractory B-cell acute lymphoblastic leukemia
- Open Access
- Research
Sha Ma, Ying Wang, Kunming Qi, Wenyi Lu, Yuekun Qi, Jiang Cao, Mingshan Niu, Depeng Li, Wei Sang, Zhiling Yan, Feng Zhu, Hai Cheng, Zhenyu Li, Mingfeng Zhao, Kailin Xu
Correction to: Dominant‑negative transforming growth factor‑β receptor‑armoured mesothelin‑targeted chimeric antigen receptor T cells slow tumour growth in a mouse model of ovarian cancer
- Open Access
- Correction
Ke Li, Jing Xu, Jing Wang, Chong Lu, Yilin Dai, Qing Dai, Wang Zhang, Congjian Xu, Shu Wu, Yu Kang
Global real-world experiences with pembrolizumab in advanced urothelial carcinoma after platinum-based chemotherapy: the ARON-2 study
- Open Access
- Research
Francesco Massari, Matteo Santoni, Hideki Takeshita, Yohei Okada, Jose Carlos Tapia, Umberto Basso, Marco Maruzzo, Sarah Scagliarini, Thomas Büttner, Giuseppe Fornarini, Zin W. Myint, Luca Galli, Vinicius Carrera Souza, Renate Pichler, Ugo De Giorgi, Nathalia Gandur, Elaine T. Lam, Danielle Gilbert, Lazar Popovic, Enrique Grande, Giulia Mammone, Rossana Berardi, Simon J. Crabb, Robert Kemp, Javier Molina-Cerrillo, Marcelo Freitas, Murilo Luz, Roberto Iacovelli, Fabio Calabrò, Deniz Tural, Francesco Atzori, Zsófia Küronya, Rita Chiari, Saul Campos, Orazio Caffo, André P. Fay, Jakub Kucharz, Paolo Andrea Zucali, José Augusto Rinck, Annalisa Zeppellini, Diogo Assed Bastos, Gaetano Aurilio, Augusto Mota, Karine Trindade, Cinzia Ortega, Juan Pablo Sade, Mimma Rizzo, Ondřej Fiala, Nuno Vau, Patrizia Giannatempo, Allan Barillas, Fernando Sabino M. Monteiro, Breno Dauster, Alessia Mennitto, Lucas Nogueira, Roni de Carvalho Fernandes, Emmanuel Seront, Luís Garcia Aceituno, Francesco Grillone, Hernan Javier Cutuli, Mauricio Fernandez, Maria Bassanelli, Ray Manneh Kopp, Giandomenico Roviello, Halima Abahssain, Giuseppe Procopio, Michele Milella, Jindrich Kopecky, Angelo Martignetti, Carlo Messina, Manuel Caitano, Eva Inman, Ravindran Kanesvaran, Daniel Herchhorn, Daniele Santini, Aristotelis Bamias, Renato Bisonni, Alessandra Mosca, Franco Morelli, Fernando Maluf, Andrey Soares, Fernando Nunes, Alvaro Pinto, Anca Zgura, Lorena Incorvaia, Jawaher Ansari, Ignacio Ortego Zabalza, Johannes Landmesser, Alessandro Rizzo, Veronica Mollica, Andrea Marchetti, Matteo Rosellini, Giulia Sorgentoni, Nicola Battelli, Sebastiano Buti, Camillo Porta, Joaquim Bellmunt
A phase I trial of autologous RAK cell immunotherapy in metastatic renal cell carcinoma
- Open Access
- Research
Jing Xu, Wen Zhang, Jinlian Tong, Caixia Liu, Qiaohui Zhang, Liren Cao, Jiangyong Yu, Aiping Zhou, Jie Ma
A2AR-mediated CXCL5 upregulation on macrophages promotes NSCLC progression via NETosis
- Open Access
- Research
Qingyang Lei, Shanshan Zhen, Lei Zhang, Qitai Zhao, Li Yang, Yi Zhang
Synergistic immunomodulatory effect of synbiotics pre- and postoperative resection of pancreatic ductal adenocarcinoma: a randomized controlled study
- Open Access
- Research
Sara Maher, Hesham A. Elmeligy, Tarek Aboushousha, Noha Said Helal, Yousra Ossama, Mahmoud Rady, Ahmed Mohamed A. Hassan, Manal Kamel
Interleukin 33 supports squamous cell carcinoma growth via a dual effect on tumour proliferation, migration and invasion, and T cell activation
- Open Access
- Research
Graziela Perri, Vanessa Garcia Vilas Boas, Maria Renata Sales Nogueira, Edgard José Franco Mello Júnior, Ana Lucia Coelho, Edwin M. Posadas, Cory Hogaboam, Karen A Cavassani, Ana Paula Campanelli
Clonal expansion of shared T cell receptors reveals the existence of immune commonality among different lesions of synchronous multiple primary lung cancer
- Open Access
- Research
Yadong Wang, Zhicheng Huang, Bowen Li, Jianchao Xue, Chao Guo, Zhongxing Bing, Zhibo Zheng, Yang Song, Yuan Xu, Guanghua Huang, Haochen Li, Xiaoqing Yu, Yankai Xia, Ruirui Li, Xiaoyan Si, Li Zhang, Ji Li, Lan Song, Yuanyuan Xiong, Dejian Gu, Mengmeng Song, Zhipeng Zhou, Rongrong Chen, Zhe Feng, Zhixin Bie, Xiaoguang Li, Huaxia Yang, Shanqing Li, Naixin Liang
New genetic insights into immunotherapy outcomes in gastric cancer via single-cell RNA sequencing and random forest model
- Open Access
- Research
Dajun Yu, Jie Yang, BinBin Wang, Zhixiang Li, Kai Wang, Jing Li, Chao Zhu
Neutrophil-activating secretome characterizes palbociclib-induced senescence of breast cancer cells
- Open Access
- Research
Gabriele Favaretto, Marianna Nicoletta Rossi, Lorenzo Cuollo, Mattia Laffranchi, Manuela Cervelli, Alessandra Soriani, Silvano Sozzani, Angela Santoni, Fabrizio Antonangeli
Expression patterns of novel immunotherapy targets in intermediate- and high-grade lung neuroendocrine neoplasms
- Open Access
- Research
Bence Ferencz, Klára Török, Orsolya Pipek, János Fillinger, Kristóf Csende, András Lantos, Radoslava Černeková, Marcel Mitták, Jozef Škarda, Patricie Delongová, Evelyn Megyesfalvi, Karin Schelch, Christian Lang, Anna Solta, Kristiina Boettiger, Luka Brcic, Jörg Lindenmann, Ferenc Rényi-Vámos, Clemens Aigner, Judit Berta, Zsolt Megyesfalvi, Balázs Döme
Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusion
- Open Access
- Review
Ke-Xun Yu, Wei-Jie Yuan, Hui-Zhen Wang, Yong-Xiang Li
