Ausgabe 6/2025
Inhalt (20 Artikel)
Association of peripheral monocytic myeloid-derived suppressor cells with molecular subtypes in single-center endometrial cancer patients receiving carboplatin + paclitaxel/avelumab (MITO-END3 trial)
- Open Access
- Research
C. D’Alterio, G. Rea, M. Napolitano, E. Coppola, A. Spina, D. Russo, R. Azzaro, C. Mignogna, G. Scognamiglio, D. Califano, L. Arenare, C. Schettino, C. Pisano, S. C. Cecere, M. Di Napoli, A. Passarelli, F. Perrone, S. Pignata, S. Scala
Clinical and dynamic circulating cytokines profile features of long-term progression-free survival benefit to immune checkpoint inhibitors in advanced non–small cell lung cancer
- Open Access
- Research
Jia-Yi Deng, Ming Gao, Xue Fan, Hong-Hong Yan, Wei-Chi Luo, Ming-Yi Yang, Xiao-Rong Yang, Zhi-Hong Chen, Chong-Rui Xu, Qing Zhou
Durable response to nivolumab in combination with regional hyperthermia in a patient with PD-L1-negative metastatic head and neck squamous cell carcinoma
- Open Access
- Research
Luc M. Berclaz, Anton Burkhard-Meier, Axel Lechner, Michael Völkl, Sinan E. Güler, Sultan Abdel-Rahman, Sina Mansoorian, Wolfgang G. Kunz, Thomas Knösel, Martin Canis, Michael von Bergwelt-Baildon, Rolf D. Issels, Dorit Di Gioia, Lars H. Lindner
Identification of SURF4 and RALGAPA1 as promising therapeutic targets in glioblastoma and pan-cancer through integrative multi-omics, CRISPR-Cas9 screening and prognostic meta-analysis
- Open Access
- Research
Fei Wang, Yuxuan Chen, Run Huang, Dengfeng Lu, Juyi Zhang, Yanbo Yang, Hanhan Dang, Meirong Liu, Zhouqing Chen, Xiaoou Sun, Zhong Wang
Prognostic nutrition index reveals LAG3 in cytotoxic CD8+ T cells and MHC class II in gastric cancer cells
- Open Access
- Research
Chikanori Tsutsumi, Kenoki Ohuchida, Masaki Imamura, Bryan Tan, Yuki Shimada, Kiwa Son, Takaaki Kosai, Naoki Katayama, Yuki Mochida, Sayuri Hayashida, Chika Iwamoto, Nobuhiro Torata, Kohei Horioka, Koji Shindo, Yusuke Mizuuchi, Naoki Ikenaga, Kohei Nakata, Yoshinao Oda, Masafumi Nakamura
Identification and validation of poor prognosis immunoevasive subtype of esophageal cancer with tumor-infiltrating SAMD3 + NK cell abundance
- Open Access
- Research
Xu Huang, Runze You, Fangyi Liu, Zitao Jian, Guanyou Zhou, Hao Yin, Mengyuan Wu, Tiantao Sun, Zhiyun Duan, Wenyi Xu, Shaoyuan Zhang, Xinyu Yang, Heng Jiao, Shuyi Yang, Qingle Wang, Jun Yin, Han Tang, Miao Lin, Lijie Tan
Correction: Efficacy and safety of lenvatinib combined with anti-PD-1 antibodies plus GEMOX chemotherapy as non-first-line systemic therapy in advanced gallbladder cancer
- Open Access
- Correction
Yang Tan, Kai Liu, Chengpei Zhu, Shanshan Wang, Yunchao Wang, Jingnan Xue, Cong Ning, Nan Zhang, Jiashuo Chao, Longhao Zhang, Junyu Long, Xiaobo Yang, Daobing Zeng, Lijin Zhao, Haitao Zhao
Combination of immune checkpoint inhibitors and anthracyclines as a potential first-line regimen for dedifferentiated liposarcoma: systematic review and meta-analysis
- Open Access
- Review
Zhuang Aobo, Zhou Xiao, Xu Chengfei, Xi Zhe, Chen Yingxue, Zhang Chenhe, Xie Fuan, Yang Fan, Xiao Mengmeng, Ye Feng, Li Wengang
USP5 motivates immunosuppressive microenvironment in multiple myeloma by activating STAT2-PFKFB4-mediated glycolysis
- Open Access
- Research
Shifeng Long, Ting Ding, Yongliang Zheng, Jinmei Shao, Yan Liu, Qinglan Wang
Ruxolitinib stopped before transplantation does not induce cytokine release in myelofibrosis
- Open Access
- Research
Sara Villar, Emmanuel Curis, Marie-Hélène Schlageter, Nelly Bosselut, Amandine Charbonnier, Marie-Thérèse Rubio, Pascal Turlure, Hélène Labussière, Jacques-Olivier Bay, Jérome Cornillon, Laure Vincent, Corentin Orvain, Jean-Jacques Kiladjian, David Michonneau, Gérard Socié, Marie Robin
Expression of the TIGIT axis and the CD39/CD73 purinergic pathway in bone metastasis-derived immune cells
- Open Access
- Research
Elias Brauneck, Leon-Gordian Leonhardt, Anne Marie Assemissen, Yagana Wahid, Moritz Kruppa, Niklas Kruppa, Julius Krüger, Stephan Menzel, Friedrich Koch-Nolte, Julian Kylies, Katja Weisel, Carsten Bokemeyer, Jasmin Wellbrock, Walter Fiedler, Lennart Viezens, Franziska Brauneck
Blockade of TIGAR prevents CD8+ T cell dysfunction and elicits anti-AML immunity
- Open Access
- Research
Jialin Cui, Wenjie Liu, Shiyang Zhong, Yiran Fang, Pei Xu, Cheng Xu, Rong Wang, Xingfei Hu, Wanting Zhou, Kening Li, Ming Hong, Sixuan Qian, Qian Sun
Multifaceted functions of tissue-resident memory T cells in tumorigenesis and cancer immunotherapy
- Open Access
- Review
Eun Sang Seo, Sung-Kyu Lee, Young Min Son
Dynamics of tertiary lymphoid structures and immune cross talk in early versus advanced colorectal cancer: potential implications for immunotherapy
- Open Access
- Research
Zixu Chen, Bang Hu, Keyu Cai, Han Gao, Zhenyu Xian, Shuang Zhang, Zhen Fang, Qian Zhou, Donglin Ren, Qi Zou
Cadonilimab, a PD-1/CTLA-4 bispecific antibody in unresectable hepatocellular carcinoma: a real-world study
- Open Access
- Research
Yilin Wang, Shida Pan, Jiahe Tian, Jianing Wang, Yingying Yu, Siyu Wang, Fengyi Li, Luo Yang, Xiaomeng Liu, Yingjuan Shen, Qin Qiu, Junqing Luan, Mengdie Jia, Chuyue Xiong, Xuanxuan Duan, Fu-Sheng Wang, Fanping Meng
Correction: Antitumor effects of immunotherapy combined with BRAF and MEK inhibitors in BRAF V600E metastatic colorectal cancer
- Open Access
- Correction
Eunyoung Tak, Hye-In An, Amy Sinyoung Lee, Kyuyoung Han, Jiwan Choi, Hyung-don Kim, Yong Sang Hong, Sun Young Kim, Eun Kyung Choi, Jeong Eun Kim, Tae Won Kim
Targeting interleukin-2-inducible T cell kinase ameliorates immune-mediated aplastic anemia
- Open Access
- Research
Weiwang Li, Yu Lian, Lele Zhang, Ruonan Li, Qian Liang, Jin Mao, Chen Qiu, Haoyuan Li, Ke Huang, Qiaoli Li, Yucan Shen, Fei Yang, Linzhu Tian, Tingfang Xiao, Shilong Gu, Hong Pan, Zhen Gao, Jingyu Zhao, Liwei Fang, Meili Ge, Weiping Yuan, Yajing Chu, Jun Shi
In situ treatment with a TLR9 agonist virus-like particle to promote immune responses against oral epithelial dysplasia progression
- Open Access
- Research
Yan Xu, Alexandra Mcmillan, Nikesh Gupta, Caitlin D. Lemke-Miltner, Aseel O. Rataan, Sudartip Areecheewakul, Divya S. Bhat, Emily A. Lanzel, Sean M. Geary, Andrean L. Simons, George J. Weiner, Aliasger K. Salem
Transcriptomic and proteomic characterization of cell and protein biomarkers of checkpoint inhibitor-induced liver injury
- Open Access
- Research
Changhua Ji, Steven Kumpf, Jessie Qian, Joel D. Federspiel, Mark Sheehan, Darien Capunitan, Edmond Atallah, Stuart Astbury, Seda Arat, Elias Oziolor, Mireia Fernandez Ocana, Shashi K. Ramaiah, Jane Grove, Guruprasad P. Aithal, Thomas A. Lanz
GD2-CAR NK-92 cell activity against neuroblastoma cells is insusceptible to TIGIT knockout
- Open Access
- Research
Wiebke Jünemann, Isabelle Bley, Laura Rekowski, Marianne Klokow, Susanne Herppich, Ingo Müller, Kerstin Cornils
