Ausgabe 7/2019
Inhalt (15 Artikel)
PLAC1: biology and potential application in cancer immunotherapy
Jafar Mahmoudian, Roya Ghods, Mahboobeh Nazari, Mahmood Jeddi-Tehrani, Mohammad Hossein Ghahremani, Nassim Ghaffari-Tabrizi-Wizsy, Seyed Nasser Ostad, Amir-Hassan Zarnani
Cryptotanshinone has curative dual anti-proliferative and immunotherapeutic effects on mouse Lewis lung carcinoma
Shuo Liu, Zhen Han, Anna L. Trivett, Hongsheng Lin, Sean Hannifin, De Yang, Joost J. Oppenheim
Inhibition of murine hepatoma tumor growth by cryptotanshinone involves TLR7-dependent activation of macrophages and induction of adaptive antitumor immune defenses
Zhen Han, Shuo Liu, Hongsheng Lin, Anna L. Trivett, Sean Hannifin, De Yang, Joost J. Oppenheim
Novel circulating tumor cell-based blood test for the assessment of PD-L1 protein expression in treatment-naïve, newly diagnosed patients with non-small cell lung cancer
Yen-Lin Chen, Wen-Chien Huang, Feng-Ming Lin, Huangpin B. Hsieh, Chia-Hsun Hsieh, Ruey Kuen Hsieh, Kuo-Wei Chen, Ming-Hong Yen, James Lee, Stephen Su, Twinkal Marfatia, Shih-En Chang, Padma Sundar, Bruce Patterson, Drew Watson, Rui Mei, Manana Javey
Checkpoint blockade immunotherapy enhances the frequency and effector function of murine tumor-infiltrating T cells but does not alter TCRβ diversity
Lindsey M. Kuehm, Kyle Wolf, John Zahour, Richard J. DiPaolo, Ryan M. Teague
Metabolic remodeling contributes towards an immune-suppressive phenotype in glioblastoma
Pravin Kesarwani, Antony Prabhu, Shiva Kant, Prakash Chinnaiyan
Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors
Katie M. Leick, Joel Pinczewski, Ileana S. Mauldin, Samuel J. Young, Donna H. Deacon, Amber N. Woods, Marcus W. Bosenberg, Victor H. Engelhard, Craig L. Slingluff Jr.
Impact of combination immunochemotherapies on progression of 4NQO-induced murine oral squamous cell carcinoma
Sonja Ludwig, Chang-Sook Hong, Beatrice M. Razzo, Kellsye P. L. Fabian, Manoj Chelvanambi, Stephan Lang, Walter J. Storkus, Theresa L. Whiteside
An HER2 DNA vaccine with evolution-selected amino acid substitutions reveals a fundamental principle for cancer vaccine formulation in HER2 transgenic mice
Richard F. Jones, Joyce D. Reyes, Heather M. Gibson, Jennifer B. Jacob, Ulka Vaishampayan, Stuart Ratner, Kang Chen, Wei-Zen Wei
Clinicopathological implications of TIM3+ tumor-infiltrating lymphocytes and the miR-455-5p/Galectin-9 axis in skull base chordoma patients
Jinpeng Zhou, Yang Jiang, Haiying Zhang, Lian Chen, Peng Luo, Long Li, Junshuang Zhao, Fei Lv, Dan Zou, Ye Zhang, Zhitao Jing
Evaluation of the efficacy of immunotherapy for non-resectable mucosal melanoma
Antoine Moya-Plana, Ruth Gabriela Herrera Gómez, Caroline Rossoni, Laurent Dercle, Samy Ammari, Isabelle Girault, Séverine Roy, Jean-Yves Scoazec, Stephan Vagner, François Janot, Alexander M. M. Eggermont, Caroline Robert
Pembrolizumab as first-line treatment for metastatic uveal melanoma
Ernesto Rossi, Monica Maria Pagliara, Daniela Orteschi, Tommaso Dosa, Maria Grazia Sammarco, Carmela Grazia Caputo, Gianluigi Petrone, Guido Rindi, Marcella Zollino, Maria Antonietta Blasi, Alessandra Cassano, Emilio Bria, Giampaolo Tortora, Giovanni Schinzari
Combination of denosumab and immune checkpoint inhibition: experience in 29 patients with metastatic melanoma and bone metastases
Yenny Angela, Sebastian Haferkamp, Carsten Weishaupt, Selma Ugurel, Jürgen C. Becker, Florian Oberndörfer, Vesna Alar, Imke Satzger, Ralf Gutzmer
Comparison of IL-2 vs IL-7/IL-15 for the generation of NY-ESO-1-specific T cells
Wenjie Gong, Jean-Marc Hoffmann, Sophia Stock, Lei Wang, Yibin Liu, Maria-Luisa Schubert, Brigitte Neuber, Angela Hückelhoven-Krauss, Ulrike Gern, Anita Schmitt, Carsten Müller-Tidow, Hiroshi Shiku, Michael Schmitt, Leopold Sellner
First-in-human phase 1 dose-escalating trial of G305 in patients with advanced solid tumors expressing NY-ESO-1
Amit Mahipal, Samuel Ejadi, Sacha Gnjatic, Seunghee Kim-Schulze, Hailing Lu, Jan H. ter Meulen, Richard Kenney, Kunle Odunsi