Ausgabe 7/2020
Inhalt (21 Artikel)
Genome-wide association study of genetic variations associated with treatment failure after intravesical bacillus Calmette–Guérin therapy for non-muscle invasive bladder cancer
Masaki Shiota, Naohiro Fujimoto, Yoshiaki Yamamoto, Ario Takeuchi, Katsunori Tatsugami, Takeshi Uchiumi, Hideyasu Matsuyama, Masatoshi Eto
Less is more: reducing the number of administered chimeric antigen receptor T cells in a mouse model using a mathematically guided approach
Anat Globerson Levin, Natalie Kronik, Tamar Shiloach, Tova Waks, Zelig Eshhar, Vladimir Vainstein
Outcomes associated with immune-related adverse events in metastatic non-small cell lung cancer treated with nivolumab: a pooled exploratory analysis from a global cohort
Abdul Rafeh Naqash, Biagio Ricciuti, Dwight H. Owen, Vaia Florou, Yukihiro Toi, Cynthia Cherry, Maida Hafiz, Andrea De Giglio, Mavish Muzaffar, Sandip H. Patel, Shunichi Sugawara, Jarred Burkart, Wungki Park, Rita Chiari, Jun Sugisaka, Gregory A. Otterson, Gilberto de Lima Lopes, Paul R. Walker
Correction to: Outcomes associated with immune-related adverse events in metastatic non-small cell lung cancer treated with nivolumab: a pooled exploratory analysis from a global cohort
Abdul Rafeh Naqash, Biagio Ricciuti, Dwight H. Owen, Vaia Florou, Yukihiro Toi, Cynthia Cherry, Maida Hafiz, Andrea De Giglio, Mavish Muzaffar, Sandip H. Patel, Shunichi Sugawara, Jarred Burkart, Wungki Park, Rita Chiari, Jun Sugisaka, Gregory A. Otterson, Gilberto de Lima Lopes, Paul R. Walker
Tumor-treating fields (TTFields) induce immunogenic cell death resulting in enhanced antitumor efficacy when combined with anti-PD-1 therapy
Tali Voloshin, Noa Kaynan, Shiri Davidi, Yaara Porat, Anna Shteingauz, Rosa S. Schneiderman, Einav Zeevi, Mijal Munster, Roni Blat, Catherine Tempel Brami, Shay Cahal, Aviran Itzhaki, Moshe Giladi, Eilon D. Kirson, Uri Weinberg, Adrian Kinzel, Yoram Palti
Adenosine-producing regulatory B cells in head and neck cancer
Sandra S. Jeske, Matthias Brand, Andreas Ziebart, Simon Laban, Johannes Doescher, Jens Greve, Edwin K. Jackson, Thomas K. Hoffmann, Cornelia Brunner, Patrick J. Schuler
Cancer testis antigen Cyclin A1 harbors several HLA-A*02:01-restricted T cell epitopes, which are presented and recognized in vivo
Anja Tatjana Teck, Sabrina Urban, Petra Quass, Annika Nelde, Heiko Schuster, Anne Letsch, Antonia Busse, Juliane Sarah Walz, Ulrich Keilholz, Sebastian Ochsenreither
Predictive value of serum VEGF levels for elderly patients or for patients with poor performance status receiving anti-PD-1 antibody therapy for advanced non-small-cell lung cancer
Ryota Shibaki, Shuji Murakami, Yuki Shinno, Yuji Matsumoto, Tatsuya Yoshida, Yasushi Goto, Shintaro Kanda, Hidehito Horinouchi, Yutaka Fujiwara, Nobuyuki Yamamoto, Noboru Yamamoto, Yuichiro Ohe
Comprehensive landscape of immune-checkpoints uncovered in clear cell renal cell carcinoma reveals new and emerging therapeutic targets
Diana Tronik-Le Roux, Mathilde Sautreuil, Mahmoud Bentriou, Jérôme Vérine, Maria Belén Palma, Marina Daouya, Fatiha Bouhidel, Sarah Lemler, Joel LeMaoult, François Desgrandchamps, Paul-Henry Cournède, Edgardo D. Carosella
Differential expression of Tim-3, PD-1, and CCR5 on peripheral T and B lymphocytes in hepatitis C virus-related hepatocellular carcinoma and their impact on treatment outcomes
Asmaa M. Zahran, Helal F. Hetta, Amal Rayan, Abeer Sharaf Eldin, Elham Ahmed Hassan, Hussein Fakhry, Ahmed Soliman, Omnia El-Badawy
Tumor immune microenvironment in cancer patients with leukocytosis
Kyung Hwan Kim, Nam Suk Sim, Jee Suk Chang, Yong Bae Kim
Regulatory T cells specifically suppress conventional CD8αβ T cells in intestinal tumors of APCMin/+ mice
Louis Szeponik, Paulina Akeus, William Rodin, Sukanya Raghavan, Marianne Quiding-Järbrink
Identification and validation of tumor environment phenotypes in lung adenocarcinoma by integrative genome-scale analysis
Guoshu Bi, Zhencong Chen, Xiaodong Yang, Jiaqi Liang, Zhengyang Hu, Yunyi Bian, Qihai Sui, Runmei Li, Cheng Zhan, Hong Fan
Upregulated immuno-modulator PD-L1 in malignant peripheral nerve sheath tumors provides a potential biomarker and a therapeutic target
Said Farschtschi, Lan Kluwe, Su-Jin Park, Su-Jun Oh, Nancy Mah, Victor-Felix Mautner, Andreas Kurtz
TNFR2+ TILs are significantly associated with improved survival in triple-negative breast cancer patients
Maya Dadiani, Daniela Necula, Smadar Kahana-Edwin, Nino Oren, Tamir Baram, Irina Marin, Dana Morzaev-Sulzbach, Anya Pavlovski, Nora Balint-Lahat, Liat Anafi, Stefan Wiemann, Cindy Korner, Einav Nili Gal-Yam, Camila Avivi, Bella Kaufman, Iris Barshack, Adit Ben-Baruch
Lauren classification identifies distinct prognostic value and functional status of intratumoral CD8+ T cells in gastric cancer
Ruochen Li, Heng Zhang, Yifan Cao, Xin Liu, Yifan Chen, Yangyang Qi, Jieti Wang, Kuan Yu, Chao Lin, Hao Liu, Hongyong He, He Li, Lingli Chen, Zhenbin Shen, Jing Qin, Weijuan Zhang, Yihong Sun, Jiejie Xu
In vivo anti-MUC1+ tumor activity and sequences of high-affinity anti-MUC1-SEA antibodies
Edward Pichinuk, Michael Chalik, Itai Benhar, Ravit Ginat-Koton, Ravit Ziv, Nechama I. Smorodinsky, Gabi Haran, Christian Garbar, Armand Bensussan, Alan Meeker, Thierry Guillaume, Daniel B. Rubinstein, Daniel H. Wreschner
A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas
Martin F. Orth, Veit Leonhard Buecklein, Eric Kampmann, Marion Subklewe, Elfriede Noessner, Florencia Cidre-Aranaz, Laura Romero-Pérez, Fabienne Sophie Wehweck, Lars Lindner, Rolf Issels, Thomas Kirchner, Annelore Altendorf-Hofmann, Thomas G. P. Grünewald, Thomas Knösel
Lymphocyte activation gene 3 (LAG3) protein expression on tumor-infiltrating lymphocytes in aggressive and TP53-mutated salivary gland carcinomas
Christoph Arolt, Moritz Meyer, Vanessa Ruesseler, Lisa Nachtsheim, Nora Wuerdemann, Thomas Dreyer, Stefan Gattenlöhner, Claus Wittekindt, Reinhard Buettner, Alexander Quaas, Jens Peter Klussmann
Tumor-associated antigen-based personalized dendritic cell vaccine in solid tumor patients
Qian-Ting Wang, Ying Nie, Sheng-Nan Sun, Tao Lin, Ru-Jin Han, Jun Jiang, Zhe Li, Jun-Qi Li, Yun-Peng Xiao, Yu-Ying Fan, Xiao-Hui Yuan, Hui Zhang, Bin-Bin Zhao, Ming Zeng, Shi-You Li, Hua-Xin Liao, Jian Zhang, You-Wen He
Correction to: Translational immune correlates of indirect antibody immunization in a randomized phase II study using scheduled combination therapy with carboplatin/paclitaxel plus oregovomab in ovarian cancer patients
Alessandra Battaglia, Alexia Buzzonetti, Marco Fossati, Giovanni Scambia, Andrea Fattorossi, Madi R. Madiyalakan, Yolanda D. Mahnke, Christopher Nicodemus