Ausgabe 9/2024
Inhalt (25 Artikel)
Long-term responders to nivolumab in previously treated advanced renal cell carcinoma: a sub-analysis of meet-URO15 study
- Open Access
- Research
Carlo Messina, Martina Catalano, Giandomenico Roviello, Annalice Gandini, Marco Maruzzo, Ugo De Giorgi, Paolo Pedrazzoli, Andrea Sbrana, Paolo Andrea Zucal, Cristina Masini, Emanuele Naglieri, Giuseppe Procopio, Michele Milella, Fabio Catalano, Lucia Fratino, Stefania Pipitone, Riccardo Ricotta, Stefano Panni, Veronica Mollica, Mariella Soraru, Veronica Prati, Francesco Atzori, Marilena Di Napoli, Marco Messina, Franco Morelli, Giuseppe Prati, Franco Nole, Andrea Malgeri, Marianna Tudini, Francesca Vignani, Alessia Cavo, Alessio Signori, Giuseppe Luigi Banna, Pasquale Rescigno, Sebastiano Buti, Sara Elena Rebuzzi, Giuseppe Fornarini
Differences in the risk of immune-related pneumonitis between PD-1 and PD-L1 inhibitors: a meta-analysis according to the new mirror-principle and PRISMA guidelines
- Open Access
- Review
Yuan Tian, Zongxiu Yin, Chi Zhang, Zhuoqi Li, Yuanyuan Wang, Kai Zhang, Feng Chen, Qi Dang
Impact of fludarabine and treosulfan on ovarian tumor cells and mesothelin chimeric antigen receptor T cells
- Open Access
- Research
Ibrahim El-Serafi, Isabella Micallef Nilsson, Alina Moter, Zhe Duan, Jonas Mattsson, Isabelle Magalhaes
Identification and validation of tumor-specific T cell receptors from tumor infiltrating lymphocytes using tumor organoid co-cultures
- Open Access
- Research
Zhilang Li, Lisha Ma, Zhaoya Gao, Xiya Wang, Xuan Che, Pengchong Zhang, Yixian Li, Qianjing Zhang, Tianxing Liu, Yuan Sun, Yun Bai, Hongkui Deng
High expression of PD-L1 on conventional dendritic cells in tumour-draining lymph nodes is associated with poor prognosis in oral cancer
- Open Access
- Research
Hjalmarsson Eric, Krzysztof Piersiala, Vilma Lagebro, Pedro Farrajota Neves Da Silva, Marianne Petro, Magnus Starkhammar, Alexandra Elliot, Rusana Bark, Gregori Margolin, Susanna Kumlien Georén, Lars-Olaf Cardell
Monocyte infiltration is an independent positive prognostic biomarker in vulvar squamous cell carcinoma
- Open Access
- Research
Ziena Abdulrahman, Kim E. Kortekaas, Marij J. P. Welters, Mariette I. E. van Poelgeest, Sjoerd H. van der Burg
A randomized phase II clinical trial of stereotactic body radiation therapy (SBRT) and systemic pembrolizumab with or without intratumoral avelumab/ipilimumab plus CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells in solid tumors
- Open Access
- Research
Manon Vounckx, Jens Tijtgat, Latoya Stevens, Iris Dirven, Bart Ilsen, Frederik Vandenbroucke, Steven Raeymaeckers, Karolien Vekens, Ramses Forsyth, Xenia Geeraerts, Ivan Van Riet, Julia Katharina Schwarze, Sandra Tuyaerts, Lore Decoster, Mark De Ridder, Ines Dufait, Bart Neyns
In vitro CAR-T cell killing: validation of the potency assay
- Open Access
- Brief Report
Claudia Piccinini, Silvia Carloni, Chiara Arienti, Elena Pancisi, Francesca Fanini, Sara Pignatta, Valentina Soldati, Monica Stefanelli, Anna Maria Granato, Giovanni Martinelli, Laura Ridolfi, Massimiliano Petrini
Altered expression of cytokines, chemokines, growth factors, and soluble receptors in patients with colorectal cancer, and correlation with treatment outcome
- Open Access
- Research
M. Stayoussef, X. Weili, A. Habel, M. Barbirou, S. Bedoui, A. Attia, Y. Omrani, K. Zouari, H. Maghrebi, W. Y. Almawi, B. Bouhaouala-Zahar, A. Larbi, B. Yacoubi-Loueslati
Engineered CD147-CAR macrophages for enhanced phagocytosis of cancers
- Open Access
- Research
Koollawat Chupradit, Saitong Muneekaew, Methichit Wattanapanitch
The significance of lipid metabolism reprogramming of tumor-associated macrophages in hepatocellular carcinoma
- Open Access
- Review
Qingjian Xie, Yuan Zeng, Xiangting Zhang, Fujun Yu
The performance status gap in immunotherapy for frail patients with advanced non-small cell lung cancer
- Open Access
- Research
Julie Tsu-Yu Wu, June Corrigan, Chloe Su, Clark Dumontier, Jennifer La, Aparjita Khan, Shipra Arya, Alex H. S. Harris, Leah Backhus, Millie Das, Nhan V. Do, Mary T. Brophy, Summer S. Han, Michael Kelley, Nathanael R. Fillmore
Systemic delivery of oncolytic herpes virus using CAR-T cells enhances targeting of antitumor immuno-virotherapy
- Open Access
- Research
Zongliang Zhang, Nian Yang, Long Xu, Huaqing Lu, Yongdong Chen, Zeng Wang, Qizhong Lu, Kunhong Zhong, Zhixiong Zhu, Guoqing Wang, Hexian Li, Meijun Zheng, Liangxue Zhou, Aiping Tong
γδ T cells in human colon adenocarcinomas comprise mainly Vδ1, Vδ2, and Vδ3 cells with distinct phenotype and function
- Open Access
- Research
William Rodin, Louis Szeponik, Tsvetanka Rangelova, Firaol Tamiru Kebede, Tobias Österlund, Patrik Sundström, Stephen Hogg, Yvonne Wettergren, Antonio Cosma, Anders Ståhlberg, Elinor Bexe Lindskog, Marianne Quiding Järbrink
Tumor-intrinsic IFNα and CXCL10 are critical for immunotherapeutic efficacy by recruiting and activating T lymphocytes in tumor microenvironment
- Open Access
- Research
Chun-Chia Cheng, Jungshan Chang, Ai-Sheng Ho, Zong-Lin Sie, Cheng-Liang Peng, Chih‑Liang Wang, Kapil Dev, Chun-Chao Chang
Tissue-resident memory CD103+CD8+ T cells in colorectal cancer: its implication as a prognostic and predictive liver metastasis biomarker
- Open Access
- Research
Shijin Liu, Penglin Wang, Peize Wang, Zhan Zhao, Xiaolin Zhang, Yunlong Pan, Jinghua Pan
GSDME-mediated pyroptosis promotes anti-tumor immunity of neoadjuvant chemotherapy in breast cancer
- Open Access
- Research
Changfang Fu, Wenbo Ji, Qianwen Cui, Anling Chen, Haiyan Weng, Nannan Lu, Wulin Yang
TRP-2 / gp100 DNA vaccine and PD-1 checkpoint blockade combination for the treatment of intracranial tumors
- Open Access
- Research
Joshua R. D. Pearson, Carles Puig-Saenz, Jubini E. Thomas, Lydia D. Hardowar, Murrium Ahmad, Louise C. Wainwright, Adam M. McVicar, Victoria A. Brentville, Chris J. Tinsley, A. Graham Pockley, Lindy G. Durrant, Stephanie E. B. McArdle
A “Prime and Expand” strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy
- Open Access
- Research
Niraj Shrestha, Michael J. Dee, Pallavi Chaturvedi, Gilles M. Leclerc, Mary Mathyer, Celeste Dufour, Laura Arthur, Michelle Becker-Hapak, Mark Foster, Ethan McClain, Natalia Valderrama Pena, Karen Kage, Xiaoyun Zhu, Varghese George, Bai Liu, Jack Egan, Christian Echeverri, Meng Wang, Lijing You, Lin Kong, Liying Li, Melissa M. Berrien-Elliott, Matthew L. Cooper, Todd A. Fehniger, Peter R. Rhode, Hing C. Wong
Blockade of the TIGIT-CD155/CD112 axis enhances functionality of NK-92 but not cytokine-induced memory-like NK cells toward CD155-expressing acute myeloid leukemia
- Open Access
- Research
Katharina Seel, Ronja Larissa Schirrmann, Daniel Stowitschek, Tamar Ioseliani, Lea Roiter, Alina Knierim, Maya C. André
In vitro T cell responses to PD-1 blockade are reduced by IFN-α but do not predict therapy response in melanoma patients
- Open Access
- Research
Laura M. Timmerman, Lobke C. M. Hensen, Mick J. M. van Eijs, Rik J. Verheijden, Karijn P. M. Suijkerbuijk, Linde Meyaard, Michiel van der Vlist, Linde Meyaard, Jürgen H. E. Kuball, Bas Oldenburg, Jeanette H. W. Leusen
Long-term survivals of immune checkpoint inhibitors as neoadjuvant and adjuvant therapy in dMMR/MSI-H colorectal and gastric cancers
- Open Access
- Research
Zhenghang Wang, Siyuan Cheng, Yanhong Yao, Shengde Liu, Zimin Liu, Ning Liu, Yongdong Jin, Yinjie Zhang, Fei Yin, Guangjie Han, Jingdong Zhang, Qiwei Wang, Dong Yan, Li Wang, Hongxia Lu, Ting Deng, Zhi Ji, Hui Gao, Weijia Fang, Hangyu Zhang, Zhiyu Chen, Jianling Zou, Yong Tang, Chunlei Xu, Jiayi Li, Huajun Qu, Liying Bao, Baoshan Cao, Xicheng Wang, Ting Xu, Yu Sun, Lin Shen, Zhi Peng, Jian Li
Correction to: The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy
- Open Access
- Correction
Wenxin Lu, Guangyu Wu, Xianyuan Miao, Jingyu Ma, Yanling Wang, Haiyan Xu, Daiyuan Shentu, Shengbai Xue, Qing Xia, Yu Wang, Liwei Wang
Correction to: New CEACAM-targeting 2A3 single-domain antibody-based chimeric antigen receptor T-cells produce anticancer effects in vitro and in vivo
- Open Access
- Correction
Iga Jancewicz, Magdalena Śmiech, Magdalena Winiarska, Radoslaw Zagozdzon, Pawel Wisniewski
Efficacy of adjuvant immune checkpoint inhibitors pembrolizumab or nivolumab in melanoma patients ≥ 75 years: results of a real-world cohort including 456 patients
- Open Access
- Research
A. Gawaz, I. Wolff, L. Nanz, L. Flatz, A. Forschner
