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Erschienen in: Current Allergy and Asthma Reports 6/2020

01.06.2020 | Asthma (V Ortega, Section Editor)

Cardiac Biomarkers in the Setting of Asthma Exacerbations: a Review of Clinical Implications and Practical Considerations

verfasst von: Kenan Yalta, Tulin Yalta, Muhammet Gurdogan, Orkide Palabıyık, Ertan Yetkın

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 6/2020

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Abstract

Purpose of Review

The present paper aims to highlight clinical implications of elevated cardiac biomarkers and associated myocardial dysfunction in a variety of cardiac and non-cardiac scenarios in patients with an asthma exacerbation, and to propose a basic algorithm for cardiovascular evaluation and triage (and hence, for further management) of these patients primarily based on evaluation of cardiac biomarkers along with basic diagnostic modalities and specific cardiac symptoms in the hospital setting.

Recent Findings

Elevation of cardiac biomarkers in the setting of an asthma exacerbation mostly signifies a new-onset subclinical myocardial dysfunction/injury generally associated with certain asthma-related factors including acute hypoxemia and bronchodilator therapy, and usually has a limited prognostic value in these patients. On the other hand, elevation of these biomarkers in patients with an asthma exacerbation might also denote a variety of certain life-threatening cardiac or non-cardiac conditions associated with significant myocardial dysfunction (acute coronary syndromes (ACSs), sepsis, etc.) that might be masked by the rampant course of the asthma exacerbation, and hence, might possibly go undetected potentially aggravating the prognosis in a portion of these patients.

Summary

In patients with an asthma exacerbation, it seems imperative to timely diagnose and manage emerging diverse clinical conditions particularly through the guidance of cardiac biomarkers and associated myocardial dysfunction patterns in an effort to improve overall prognosis in these patients.
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Metadaten
Titel
Cardiac Biomarkers in the Setting of Asthma Exacerbations: a Review of Clinical Implications and Practical Considerations
verfasst von
Kenan Yalta
Tulin Yalta
Muhammet Gurdogan
Orkide Palabıyık
Ertan Yetkın
Publikationsdatum
01.06.2020
Verlag
Springer US
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 6/2020
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-020-00909-5

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