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Critical Care

Erschienen in:

01.02.2006 | Letter

Cardiac troponin level is not an independent predictor of mortality in septic patients requiring medical intensive care unit admission

verfasst von: François G Brivet, Frédéric M Jacobs, Patrice Colin, Dominique Prat, Bogdan Grigoriu

Erschienen in: Critical Care | Ausgabe 1/2006

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Excerpt

Turley and Gedney claim that the cardiac troponin Ic level is a predictor of adverse outcome [1] and that their results support those of King and colleagues [2]. Unfortunately, King and colleagues were unable to demonstrate a link between the troponin Ic level and mortality when using a multivariate model including the Acute Physiology Age and Chronic Health Evaluation II score. Interpretation of the results of Turley and Gedney therefore requires caution since their results are based only on univariate analysis [1]. …

Turley AJ, Gedney JA: Role of cardiac troponin as a prognosticator in critically ill patients [letter]. Crit Care 2005, 9: E30. 10.1186/cc3920PubMedCentralCrossRefPubMed

King DA, Codish S, Novack V, Barski L, Almag Y: The role of cardiac troponin I as a prognosticator in critically ill medical patients: a prospective observational cohort study. Crit Care 2005, 9: R390-R395. 10.1186/cc3731PubMedCentralCrossRefPubMed

Mehta NJ, Khan IA, Gupta V, Jani K, Gowda RM, Smith PR: Cardiac troponin I predicts myocardial dysfunction and adverse outcome in septic shock. Int J Cardiol 2004, 95: 13-17. 10.1016/j.ijcard.2003.02.005CrossRefPubMed

Fenton KE, Sable CA, Bell MJ, Patel KM, Berger JT: Increases in serum levels of troponin are associated with cardiac dysfunction and disease severity in pediatric patients with septic shock. Pediatr Crit Care Med 2004, 5: 533-538. 10.1097/01.PCC.0000144711.97646.0CCrossRefPubMed

Wu TT, Yuan A, Chen CY, Chen WJ, Luh KT, Kuo SH, Lin FY, Yang PC: Cardiac troponin I levels are a risk factor for mortality and multiple organ failure in non cardiac critically ill patients and have an additive effect tot the APACHE II score in outcome prediction. Shock 2004, 22: 95-101. 10.1097/01.shk.0000132484.97424.32CrossRefPubMed

Ver Elst KM, Spaper HD, Nguyen DN, Garbar C, Huyghens LP, Gorus FK: Cardiac troponins I and T are biological markers of left ventricular dysfunction in septic shock. Clin Chem 2000, 46: 650-657.PubMed

Lim W, Qushmaq I, Cook DJ, Crowther MA, Heels-Ansdell D, Devereaux PJ, Troponin T Trials Group: Elevated troponin and myocardial infarction in the intensive care unit: a prospective study. Crit Care 2005, 9: R636-R644. 10.1186/cc3816PubMedCentralCrossRefPubMed

Titel: Cardiac troponin level is not an independent predictor of mortality in septic patients requiring medical intensive care unit admission
verfasst von: François G Brivet
Frédéric M Jacobs
Patrice Colin
Dominique Prat
Bogdan Grigoriu
Publikationsdatum: 01.02.2006
Verlag: BioMed Central
Erschienen in: Critical Care / Ausgabe 1/2006
Elektronische ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc3990

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Cardiac troponin level is not an independent predictor of mortality in septic patients requiring medical intensive care unit admission

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