What is Known:
• Academic performance is associated with both, cardiorespiratory fitness and weight status.
• The role of weight status in the association between cardiorespiratory fitness and academic performance is poorly understood.
What is New:
• We support the scarce research investigating the mediating role of weight status as mechanism in the association between fitness and academic performance in youth.
• Previous knowledge is expanded by suggesting that cardiorespiratory fitness is related to weight status which in turn may positively influence academic performance in adolescents.