The authors declared that they have no competing interests.
MCW, EN, FW, KB, CW, PS examined and treated the patient and collected the data. FWN, MCW, CW, RL, TM, KTM, KB, PS discussed the case and data. MCW, CW, PS, KB wrote the manuscript. All authors read and approved the final manuscript.
The Oral Squamous Cell Carcinoma (OSCC) frequently metastasizes lymphogenously. Haematogenous dissemination is less common. This report describes a rare case of a metastatic OSCC of the floor of the mouth to the patients’ left upper arm. To our knowledge this is the first of such case described in the literature.
Twelve months after R0 tumor resection surgery, including microvascular reconstruction of the lower jaw followed by adjuvant radiotherapy, the patient was admitted for osteosynthesis plates removal. During clinical examination a tumor located at his left upper arm was detected. According to the patient the tumor has demonstrated rapid growth. Macroscopic appearance and conventional imaging led to the differential diagnosis of an abscess. MR-imaging could not differentiate between a tumor of soft tissue origin and a metastasis. A biopsy was taken and the pathological examination confirmed the diagnosis of an OSCC metastasis. The postoperative interdisciplinary tumor board recommended radiation therapy.
Due to the fact that patients with regional lymph node metastases have a higher probability to develop distant metastasis a more detailed screening might be considered – especially when hemangiosis carcinomatosa was histologically or macroscopically found.
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- Case report: upper arm metastasis of an oral squamous cell carcinoma
Matthias Christian Wurm
Konstantinos Theodorou Mitsimponas
Cornelius von Wilmowsky
- BioMed Central
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