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Erschienen in: Indian Journal of Hematology and Blood Transfusion 1/2016

13.01.2015 | Case Report

CD56 Negative Aggressive T Cell Large Granular Lymphocytic Leukemia

verfasst von: Mary Theresa Sylvia, Sajini Elizabeth Jacob, Debdatta Basu, Deepak Amalnath, Tarun Kumar Dutta

Erschienen in: Indian Journal of Hematology and Blood Transfusion | Sonderheft 1/2016

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Abstract

T cell large granular lymphocytic leukemia is a clonal proliferation of cytotoxic large granular T cells positive for CD3 and CD8. It is a chronic lymphoproliferative disorder with an indolent course. Therapeutic options include observation and low dose chemotherapy. Rarely, they have an aggressive course. Such cases have expression of NK cell associated antigens like CD56 in the T cells. These cases require more aggressive therapy with acute lymphoblastic leukemia regimens. We report a case of fatal CD56 negative T cell large granular lymphocytic leukemia in a 38 year old lady.
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Metadaten
Titel
CD56 Negative Aggressive T Cell Large Granular Lymphocytic Leukemia
verfasst von
Mary Theresa Sylvia
Sajini Elizabeth Jacob
Debdatta Basu
Deepak Amalnath
Tarun Kumar Dutta
Publikationsdatum
13.01.2015
Verlag
Springer India
Erschienen in
Indian Journal of Hematology and Blood Transfusion / Ausgabe Sonderheft 1/2016
Print ISSN: 0971-4502
Elektronische ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-015-0502-9

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