Ausgabe 1/2025
Inhalt (16 Artikel)
A systematic review on the culture methods and applications of 3D tumoroids for cancer research and personalized medicine
- Open Access
- Review
Jessica Kalla, Janette Pfneissl, Theresia Mair, Loan Tran, Gerda Egger
Acidity and hypoxia of tumor microenvironment, a positive interplay in extracellular vesicle release by tumor cells
- Open Access
- Review
Silvia Peppicelli, Lido Calorini, Francesca Bianchini, Laura Papucci, Lucia Magnelli, Elena Andreucci
BHLHE41, a transcriptional repressor involved in physiological processes and tumor development
- Open Access
- Review
Caroline Bret, Fabienne Desmots-Loyer, Jérôme Moreaux, Thierry Fest
Suppressing SENP1 inhibits esophageal squamous carcinoma cell growth via SIRT6 SUMOylation
- Open Access
- Research
Jianmin Gu, Shaoyuan Zhang, Dong Lin, Wenhan Wang, Jinke Cheng, Quan Zheng, Hao Wang, Lijie Tan
ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity
- Open Access
- Research
Irene Zamora, Mirian Gutiérrez, Alex Pascual, María J. Pajares, Miguel Barajas, Lillian M. Perez, Sungyong You, Beatrice S. Knudsen, Michael R. Freeman, Ignacio J. Encío, Mirja Rotinen
OrganoIDNet: a deep learning tool for identification of therapeutic effects in PDAC organoid-PBMC co-cultures from time-resolved imaging data
- Open Access
- Research
Nathalia Ferreira, Ajinkya Kulkarni, David Agorku, Teona Midelashvili, Olaf Hardt, Tobias J. Legler, Philipp Ströbel, Lena-Christin Conradi, Frauke Alves, Fernanda Ramos-Gomes, M. Andrea Markus
Antitumor activity of afatinib in EGFR T790M-negative human oral cancer therapeutically targets mTOR/Mcl-1 signaling axis
- Open Access
- Research
Jung-Min Han, Kyu-Young Oh, Su-Jung Choi, Won-Woo Lee, Bo-Hwan Jin, Ji-Hoon Kim, Hyun-Ju Yu, Ryan Jin Young Kim, Hye-Jung Yoon, Jae-Il Lee, Seong-Doo Hong, Sung-Dae Cho
Comprehensive multiomics analysis of the signatures of gastric mucosal bacteria and plasma metabolites across different stomach microhabitats in the development of gastric cancer
- Open Access
- Research
Bingsen Wang, Jiahui Luan, Weidong Zhao, Junbao Yu, Anqing Li, Xinxin Li, Xiaoqin Zhong, Hongyun Cao, Ruicai Wang, Bo Liu, Shiyong Lu, Mei Shi
Fasting in combination with the cocktail Sorafenib:Metformin blunts cellular plasticity and promotes liver cancer cell death via poly-metabolic exhaustion
- Open Access
- Research
Juan L. López-Cánovas, Beatriz Naranjo-Martínez, Alberto Diaz-Ruiz
Loss of histone deubiquitinase Bap1 triggers anti-tumor immunity
- Open Access
- Research
Hong Chang, Mingxia Li, Linlin Zhang, Meng Li, Swee Hoe Ong, Zhiwei Zhang, Jie Zheng, Xiang Xu, Yu Zhang, Jing Wang, Xingjie Liu, Kairui Li, Yao Luo, Haiyun Wang, Zhichao Miao, Xi Chen, Jie Zha, Yong Yu
Pre-existing cell subpopulations in primary prostate cancer tumors display surface fingerprints of docetaxel-resistant cells
- Open Access
- Research
Stanislav Drápela, Barbora Kvokačková, Eva Slabáková, Anna Kotrbová, Kristína Gömöryová, Radek Fedr, Daniela Kurfürstová, Martin Eliáš, Vladimír Študent jr, Frederika Lenčéšová, Ganji Sri Ranjani, Vendula Pospíchalová, Vítězslav Bryja, Wytske M. van Weerden, Martin Puhr, Zoran Culig, Jan Bouchal, Karel Souček
Next-generation BCMA-targeted chimeric antigen receptor CARTemis-1: the impact of manufacturing procedure on CAR T-cell features
- Open Access
- Research
Belén Sierro-Martínez, Virginia Escamilla-Gómez, Laura Pérez-Ortega, Beatriz Guijarro-Albaladejo, Paola Hernández-Díaz, María de la Rosa-Garrido, Maribel Lara-Chica, Alfonso Rodríguez-Gil, Juan Luis Reguera-Ortega, Luzalba Sanoja-Flores, Blanca Arribas-Arribas, Miguel Ángel Montiel-Aguilera, Gloria Carmona, Maria Jose Robles, Teresa Caballero-Velázquez, Javier Briones, Hermann Einsele, Michael Hudecek, Jose Antonio Pérez-Simón, Estefanía García-Guerrero
Telomere transcripts act as tumor suppressor and are associated with favorable prognosis in colorectal cancer with low proliferating cell nuclear antigen expression
- Open Access
- Brief Report
Philip Kienzl, Abigail J. Deloria, Monika Hunjadi, Juliane M. Hadolt, Max-Felix Haering, Angrit Bothien, Doris Mejri, Medina Korkut-Demirbaş, Sandra Sampl, Gerhard Weber, Christine Pirker, Severin Laengle, Tamara Braunschmid, Eleni Dragona, Brigitte Marian, Sarantis Gagos, Lingeng Lu, Jeremy D. Henson, Loretta M. S. Lau, Roger R. Reddel, Wolfgang Mikulits, Stefan Stättner, Klaus Holzmann
Low-dose SAHA enhances CD8+ T cell-mediated antitumor immunity by boosting MHC I expression in non-small cell lung cancer
- Open Access
- Research
Wenqian Dong, Bing He, Yanhong Cao, Rui Yang, Shuang Zhang, Yujie Kong, Dapeng Lu, Xu Zheng, Yanjiao Hou, Maoxin Zhu, Chen Wang, Shihao Yu, Dechun Cui, Hao Wang, Baolong Wang
Retraction Note: Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2
- Retraction Note
Yunxiu Huang, Qianni Jin, Min Su, Feihu Ji, Nian Wang, Changli Zhong, Yulin Jiang, Yifeng Liu, Zhiqian Zhang, Junhong Yang, Lan Wei, Tingmei Chen, Bing Li
Retraction Note: Downregulation of beta-catenin in chemo-tolerant TNBC through changes in receptor and antagonist profiles of the WNT pathway: Clinical and prognostic implications
- Retraction Note
Saimul Islam, Hemantika Dasgupta, Mukta Basu, Anup Roy, Neyaz Alam, Susanta Roychoudhury, Chinmay Kumar Panda
