Ausgabe 3/2024
Inhalt (21 Artikel)
DNA repair in tumor radioresistance: insights from fruit flies genetics
- Review
Antonella Porrazzo, Matteo Cassandri, Andrea D’Alessandro, Patrizia Morciano, Rossella Rota, Francesco Marampon, Giovanni Cenci
NK cells as powerful therapeutic tool in cancer immunotherapy
- Review
Mao Huang, Yixuan Liu, Qijia Yan, Miao Peng, Junshang Ge, Yongzhen Mo, Yumin Wang, Fuyan Wang, Zhaoyang Zeng, Yong Li, Chunmei Fan, Wei Xiong
Omics-based molecular classifications empowering in precision oncology
- Review
Zhaokai Zhou, Ting Lin, Shuang Chen, Ge Zhang, Yudi Xu, Haijiao Zou, Aoyang Zhou, Yuyuan Zhang, Siyuan Weng, Xinwei Han, Zaoqu Liu
TRPV1 inhibition suppresses non-small cell lung cancer progression by inhibiting tumour growth and enhancing the immune response
- Research
Yang Wang, Yu Zhang, Jing Ouyang, Hanying Yi, Shiyu Wang, Dongbo Liu, Yingying Dai, Kun Song, Wenwu Pei, Ziyang Hong, Ling Chen, Wei Zhang, Zhaoqian Liu, Howard L. Mcleod, Yijing He
TIPRL1 and its ATM-dependent phosphorylation promote radiotherapy resistance in head and neck cancer
- Research
Célie Cokelaere, Rüveyda Dok, Emanuela E. Cortesi, Peihua Zhao, Anna Sablina, Sandra Nuyts, Rita Derua, Veerle Janssens
E3 ligase SOCS3 regulates NOD2 expression by ubiquitin proteasome system in lung cancer progression
- Research
In-ho Jeong, Jae Kwang Yun, Jun-O Jin, Jeong Hee Hong, Ji Yeon Lee, Geun Dong Lee, Peter Chang-Whan Lee
Silencing AHNAK promotes nasopharyngeal carcinoma progression by upregulating the ANXA2 protein
- Research
Xingxing Lu, Yan Mei, Chunmei Fan, Pan Chen, Xiayu Li, Zhaoyang Zeng, Guiyuan Li, Wei Xiong, Bo Xiang, Mei Yi
CHIP promotes CAD ubiquitination and degradation to suppress the proliferation and colony formation of glioblastoma cells
- Research
Guanya Li, Kai Xiao, Yinan Li, Jianfang Gao, Shanping He, Tingting Li
Stiffened tumor microenvironment enhances perineural invasion in breast cancer via integrin signaling
- Research
Bing Han, Xin Guan, Mingyue Ma, Baoling Liang, Linglie Ren, Yutong Liu, Ye Du, Shu-Heng Jiang, Dong Song
The development of in vitro organotypic 3D vulvar models to study tumor-stroma interaction and drug efficacy
- Research
Shidi Wu, Bertine W. Huisman, Marion H. Rietveld, Robert Rissmann, Maarten H. Vermeer, Mariette I. E. van Poelgeest, Abdoelwaheb El Ghalbzouri
CSGALNACT2 restricts ovarian cancer migration and invasion by modulating MAPK/ERK pathway through DUSP1
- Open Access
- Research
Mingjun Ma, Chao Wang, Meixuan Wu, Sijia Gu, Jiani Yang, Yue Zhang, Shanshan Cheng, Shilin Xu, Minghai Zhang, Yongsong Wu, Yaqian Zhao, Xiu Tian, Dominic Chih-Cheng Voon, Chiaki Takahashi, Jindan Sheng, Yu Wang
HPV16 E6/E7-mediated regulation of PiwiL1 expression induces tumorigenesis in cervical cancer cells
- Research
Midhunaraj Kunnummal, Pooja Sherly Raveendran, Budhaditya Basu, Sheri Vidya Rani, Riya Ann Paul, Krithiga Kuppusamy, Mary Angelin, Joby Issac, Jackson James, Ani V. Das
ATF3-induced activation of NF-κB pathway results in acquired PARP inhibitor resistance in pancreatic adenocarcinoma
- Research
Yang Liu, Yizhi Cao, Pengyi Liu, Shuyu Zhai, Yihao Liu, Xiaomei Tang, Jiayu Lin, Minmin Shi, Debin Qi, Xiaxing Deng, Youwei Zhu, Weishen Wang, Baiyong Shen
ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures
- Research
Jiaoduan Li, Dongyan Cao, Lixin Jiang, Yiwen Zheng, Siyuan Shao, Ai Zhuang, Dongxi Xiang
Sirtuin 5-mediated deacetylation of TAZ at K54 promotes melanoma development
- Research
Garam Kim, Poshan Yugal Bhattarai, Sung-Chul Lim, Kwang Youl Lee, Hong Seok Choi
OTUB1 accelerates hepatocellular carcinoma by stabilizing RACK1 via its non-canonical ubiquitination
- Open Access
- Research
Liqun Peng, Tiangen Wu, Yingyi Liu, Dongli Zhao, Wenzhi He, Yufeng Yuan
Pathological response and tumor stroma immunogenic features predict long-term survival in non-small cell lung cancer after neoadjuvant chemotherapy
- Research
Shuaibo Wang, Xujie Sun, Jiyan Dong, Li Liu, Hao Zhao, Renda Li, Zhenlin Yang, Na Cheng, Yalong Wang, Li Fu, Hang Yi, Zhuoheng Lv, Huandong Huo, Donghui Jin, Yousheng Mao, Lin Yang
O-GlcNAcylation of TRIM29 and OGT translation forms a feedback loop to promote adaptive response of PDAC cells to glucose deficiency
- Research
Fu-Ying Zhao, Xue Chen, Jia-Mei Wang, Ye Yuan, Chao Li, Jia Sun, Hua-Qin Wang
Targeting MEK/COX-2 axis improve immunotherapy efficacy in dMMR colorectal cancer with PIK3CA overexpression
- Research
Kunwei Peng, Yongxiang Liu, Shousheng Liu, Zining Wang, Huanling Zhang, Wenzhuo He, Yanan Jin, Lei Wang, Xiaojun Xia, Liangping Xia
Extracellular vesicles related gene HSPH1 exerts anti-tumor effects in prostate cancer via promoting the stress response of CD8 + T cells
- Brief Report
Xinrui Wu, Yinjie Zhu, Cong Hu, Xinxing Du, Wei Xue, Yonghui Chen, Liang Dong, Jiahua Pan
Asymmetric post-translational modifications regulate the nuclear translocation of STAT3 homodimers in response to leukemia inhibitory factor
- Open Access
- Brief Report
Mickael Diallo, Constança Pimenta, Fernanda Murtinheira, Daniela Martins-Alves, Francisco R. Pinto, André Abrantes da Costa, Ricardo Letra-Vilela, Vanesa Martin, Carmen Rodriguez, Mário S. Rodrigues, Federico Herrera
