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Cellular Oncology

The official journal of the International Society for Cellular Oncology

Cellular Oncology OnlineFirst articles

15.01.2019 | Original Paper

Concomitant dysregulation of the estrogen receptor and BRAF/MEK signaling pathways is common in colorectal cancer and predicts a worse prognosis

Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide [ 1 , 2 ]. It has amply been shown that several genes, including APC , TP53 , KRAS and BRAF , are frequently mutated in CRC and play important roles in the initiation …

15.01.2019 | Review

MicroRNA-mediated redox regulation modulates therapy resistance in cancer cells: clinical perspectives

Cancer is a major public health problem. In 2018 it has caused more than 9.6 million deaths as reported by the World Health Organization WHO. Chemotherapy and radiation therapy are the most commonly used therapeutic strategies, but the development …

03.01.2019 | Original Paper

Nanoquinacrine sensitizes 5-FU-resistant cervical cancer stem-like cells by down-regulating Nectin-4 via ADAM-17 mediated NOTCH deregulation

Cervical cancer (CC) is the fourth most frequently observed cancer in women and has a high mortality incidence [ 1 , 2 ]. The chemotherapy regimen of CC includes 5-Fluorouracil (5-FU), an anti-metabolite, which is also widely used in treating many …

11.12.2018 | Original Article

Interfering with bromodomain epigenome readers as therapeutic option in mucoepidermoid carcinoma

Mucoepidermoid carcinoma (MEC) represents the most common primary malignant salivary gland tumor [ 1 – 4 ]. Salivary gland tumors comprise a heterogeneous group of lesions accounting for less than 1% of all tumors and between 3 and 5% of all head …

19.11.2018 | Original Paper

CCR5 blockage by maraviroc: a potential therapeutic option for metastatic breast cancer

Breast cancer is the most frequently diagnosed malignancy in women and the 2 nd leading cause of cancer-related mortality worldwide [ 1 , 2 ]. Early diagnosis and new surgical strategies have played major roles in improving the survival of primary …

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Über diese Zeitschrift

Cellular Oncology publishes scientific contributions from various biomedical and clinical disciplines involved in basic and translational cancer research on the cell and tissue level, technical and bioinformatics developments in this area, and clinical applications. This includes a variety of fields like genome technology, micro-arrays and other high-throughput techniques, genomic instability, SNP, DNA methylation, signaling pathways, DNA organization, (sub)microscopic imaging, proteomics, bioinformatics, functional effects of genomics, drug design and development, molecular diagnostics and targeted cancer therapies, genotype-phenotype interactions.

A major goal is to translate the latest developments in these fields from the research laboratory into routine patient management. To this end Cellular Oncology forms a platform of scientific information exchange between molecular biologists and geneticists, technical developers, pathologists, (medical) oncologists and other clinicians involved in the management of cancer patients.

In vitro studies are preferentially supported by validations in tumor tissue with clinicopathological associations.

Weitere Informationen

Neu im Fachgebiet Pathologie

27.11.2018 | Hauptreferate: Tumorevolution II | Sonderheft 2/2018

Zirkulierende Tumorzellen beim Pankreaskarzinom

Ergebnisse morphologischer und molekularer Analysen und Vergleiche mit dem Primärtumor

23.11.2018 | Hauptreferate: Hauptprogramm der DGP | Sonderheft 2/2018

Das Urachuskarzinom – aktuelle Konzepte einer seltenen Tumorerkrankung

16.11.2018 | Hauptreferate: Hauptprogramm der DGP | Sonderheft 2/2018

Das Deutsche Mesotheliomregister

Aktuelle pathologische Diagnostik und Leistungen

14.11.2018 | Originalien | Ausgabe 6/2018

Retinale Blutungen beim Schütteltrauma

Differenzialdiagnostische Aspekte