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Cellular Oncology

The official journal of the International Society for Cellular Oncology

Cellular Oncology OnlineFirst articles

07.03.2018 | Original Paper

Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors

ZEB2, also known as SMAD Interacting Protein 1 (SIP1), is a member of the ZEB family of transcription factors and is encoded by the ZFHX1B gene on chromosome 2 [ 1 ]. The ZEB family proteins contain a SMAD binding domain, a homeodomain and two …

01.03.2018 | Original Paper

Cancer-associated fibroblasts affect breast cancer cell gene expression, invasion and angiogenesis

The acquisition of a malignant phenotype does not depend exclusively on intrinsic cancer cell properties, but also on stromal features [ 1 ]. Cancer associated fibroblasts (CAFs), one of the most abundant cell types within the breast cancer stroma …

28.02.2018 | Original Paper

Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner

Putrescine (Put), spermidine (Spd) and spermine (Spm) are natural polyamines (PAs) with essential roles in cell proliferation, growth and differentiation. Increased intracellular PA levels have, however, been found to be associated with cancer …

28.02.2018 | Original Paper Open Access

A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells

Glioblastoma (GBM) is a World Health Organization (WHO) defined grade IV astrocytoma, which is the most aggressive form of glioma [ 1 ]. Despite notable achievements that have been made in the past, the clinical management of GBM patients is still …

26.02.2018 | Report

Diagnostic and prognostic relevance of salivary microRNA-21, -125a, -31 and -200a levels in patients with oral lichen planus - a short report

Lichen planus is a chronic inflammatory disease of mucous membranes. This disease affects 1 to 2% of the general population. In the oral cavity, buccal mucosa, tongue and gingiva are commonly affected. Other parts may be affected as well [ 1 ]. The …

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Über diese Zeitschrift

Cellular Oncology publishes scientific contributions from various biomedical and clinical disciplines involved in basic and translational cancer research on the cell and tissue level, technical and bioinformatics developments in this area, and clinical applications. This includes a variety of fields like genome technology, micro-arrays and other high-throughput techniques, genomic instability, SNP, DNA methylation, signaling pathways, DNA organization, (sub)microscopic imaging, proteomics, bioinformatics, functional effects of genomics, drug design and development, molecular diagnostics and targeted cancer therapies, genotype-phenotype interactions.

A major goal is to translate the latest developments in these fields from the research laboratory into routine patient management. To this end Cellular Oncology forms a platform of scientific information exchange between molecular biologists and geneticists, technical developers, pathologists, (medical) oncologists and other clinicians involved in the management of cancer patients.

In vitro studies are preferentially supported by validations in tumor tissue with clinicopathological associations.

Weitere Informationen

Neu im Fachgebiet Pathologie

02.02.2018 | Schwerpunkt: Kopf-Hals-Tumoren | Ausgabe 1/2018

Sinunasale Tumoren

Neues aus der WHO mit besonderem Fokus auf neue mesenchymale Entitäten

01.02.2018 | CME | Ausgabe 1/2018

Nebenwirkungen anaboler Substanzen

01.02.2018 | Review articles | Ausgabe 1/2018

Evidential power and explanatory gap in forensic imaging