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Cellular Oncology

The official journal of the International Society for Cellular Oncology

Cellular Oncology OnlineFirst articles

17.05.2019 | Report Open Access

Stromal organization as predictive biomarker for the treatment of colon cancer with adjuvant bevacizumab; a post-hoc analysis of the AVANT trial

Over a decade ago bevacizumab, a humanized anti-VEFG monoclonal antibody, was introduced as a new therapeutic agent for metastatic colon cancer. Since then, limited progress in systemic treatment of colon cancer has been made. Maximum utilization …

14.05.2019 | Original Paper Open Access

Inhibition of CBP/β-catenin and porcupine attenuates Wnt signaling and induces apoptosis in head and neck carcinoma cells

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Unfortunately, recurrence following conventional treatment, including surgery, radiotherapy, chemotherapy, or combined therapy occurs relatively frequently …

25.04.2019 | Original paper

The ERBB receptor inhibitor dacomitinib suppresses proliferation and invasion of pancreatic ductal adenocarcinoma cells

Pancreatic ductal adenocarcinoma (PDAC), the most common malignancy of the pancreas, is the fourth leading cause of cancer-related death in the USA. 55,440 new cases and 44,330 deaths have been reported in the USA in 2018, which highlights its …

23.04.2019 | Original Paper Open Access

Hypo-phosphorylated CD147 promotes migration and invasion of hepatocellular carcinoma cells and predicts a poor prognosis

Hepatocellular carcinoma (HCC) is one of the most common malignancies and one of the most frequent causes of cancer-related death in the world [ 1 ]. Despite significant improvements in both diagnostic and therapeutic modalities, metastasis is …

17.04.2019 | Original Paper

Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages and head and neck squamous cell carcinoma cells

Currently, the treatment options for head and neck squamous cell carcinoma (HNSCC) are diverse, the most common methods being surgery, chemotherapy and radiotherapy. Molecular targeted therapy represents another effective means of supplemental or …

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Über diese Zeitschrift

Cellular Oncology publishes scientific contributions from various biomedical and clinical disciplines involved in basic and translational cancer research on the cell and tissue level, technical and bioinformatics developments in this area, and clinical applications. This includes a variety of fields like genome technology, micro-arrays and other high-throughput techniques, genomic instability, SNP, DNA methylation, signaling pathways, DNA organization, (sub)microscopic imaging, proteomics, bioinformatics, functional effects of genomics, drug design and development, molecular diagnostics and targeted cancer therapies, genotype-phenotype interactions.

A major goal is to translate the latest developments in these fields from the research laboratory into routine patient management. To this end Cellular Oncology forms a platform of scientific information exchange between molecular biologists and geneticists, technical developers, pathologists, (medical) oncologists and other clinicians involved in the management of cancer patients.

In vitro studies are preferentially supported by validations in tumor tissue with clinicopathological associations.

Weitere Informationen

Neu im Fachgebiet Pathologie

14.03.2019 | Originalien | Ausgabe 2/2019

Medikamentennachweise bei bayerischen Altenheimbewohnern – eine rechtsmedizinische Analyse

Erste Ergebnisse aus Screeninguntersuchungen an Urinproben

07.03.2019 | Mammakarzinom | CME | Ausgabe 2/2019

Update der S3-Leitlinie Mammakarzinom

Was gibt es Neues für Pathologen?

21.02.2019 | Schwerpunkt: Neuropathologie | Ausgabe 2/2019

Neuropathologie der Medulloblastome und anderer embryonaler Tumoren des ZNS

Präzisierung der Diagnostik durch Integration genetischer Marker