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Erschienen in: Journal of General Internal Medicine 1/2018

07.08.2017 | Editorial

CHAD is Dead: Pragmatic Utility of the CHA2DS2-VASc Score in Non-Valvular Atrial Fibrillation?

verfasst von: T. Raymond Foley, MD, Mori J. Krantz, MD

Erschienen in: Journal of General Internal Medicine | Ausgabe 1/2018

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Excerpt

The CHADS2 score and its second iteration, CHA2DS2-VASc, are ubiquitous in clinical decisions pertaining to assessment of a patient’s thromboembolic risk from non-valvular atrial fibrillation (AF). Clinicians rely on these scores when deciding whether to prescribe long-term oral anticoagulation (OAC) for AF patients, weighing the bleeding risks of OAC against the actuarial risk of an embolic stroke. However, societal guidelines have incrementally expanded indications for anticoagulant use through the addition of novel risk factors and lowering the threshold for initiation of OAC.1 In fact, O’Brien et al. recently demonstrated that 91% of patients with non-valvular AF now have a guideline-based indication for anticoagulation.2 Despite the overwhelming eligibility patients for OAC, a recent retrospective study of patients with non-valvular AF who suffered an acute ischemic stroke demonstrated that only 16% of eligible stroke patients were receiving therapeutic anticoagulation.3 Given this background, we argue that:
1.
The clinician's focus should be on when to initiate OAC, or alternatively, on identifying those rare circumstances in which not to initiate OAC.
 
2.
The CHADS2 and CHA2DS2-VASc scores may not be relevant for clinical decision-making.
 
3.
Risk scores foster clinical inertia, creating a barrier to guideline-directed care.
 
Literatur
1.
Zurück zum Zitat January CT, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014; 64(21): e1–7.CrossRef January CT, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014; 64(21): e1–7.CrossRef
2.
Zurück zum Zitat O’Brien EC, et al. Effect of the 2014 atrial fibrillation guideline revisions on the proportion of patients recommended for oral anticoagulation. JAMA Intern Med. 2015; 175(5): 848–850.CrossRef O’Brien EC, et al. Effect of the 2014 atrial fibrillation guideline revisions on the proportion of patients recommended for oral anticoagulation. JAMA Intern Med. 2015; 175(5): 848–850.CrossRef
3.
Zurück zum Zitat Xian Y et al. Association of preceding antithrombotic treatment with acute ischemic stroke severity and in-hospital outcomes among patients with atrial fibrillation. JAMA. 2017; 317(10): 1057–1067.CrossRef Xian Y et al. Association of preceding antithrombotic treatment with acute ischemic stroke severity and in-hospital outcomes among patients with atrial fibrillation. JAMA. 2017; 317(10): 1057–1067.CrossRef
4.
Zurück zum Zitat Chen JY, et al., CHADS2 versus CHA2DS2-VASc score in assessing the stroke and thromboembolism risk stratification in patients with atrial fibrillation: a systematic review and meta-analysis. J Geriatr Cardiol. 2013: 10(3): 258–66.PubMedPubMedCentral Chen JY, et al., CHADS2 versus CHA2DS2-VASc score in assessing the stroke and thromboembolism risk stratification in patients with atrial fibrillation: a systematic review and meta-analysis. J Geriatr Cardiol. 2013: 10(3): 258–66.PubMedPubMedCentral
5.
Zurück zum Zitat Cifu A, Prasad V. Wearables, smartphones and novel anticoagulants: We will treat more atrial fibrillation, but will patients be better off? J Gen Intern Med. 2016;31(11):1367–8.CrossRef Cifu A, Prasad V. Wearables, smartphones and novel anticoagulants: We will treat more atrial fibrillation, but will patients be better off? J Gen Intern Med. 2016;31(11):1367–8.CrossRef
Metadaten
Titel
CHAD is Dead: Pragmatic Utility of the CHA2DS2-VASc Score in Non-Valvular Atrial Fibrillation?
verfasst von
T. Raymond Foley, MD
Mori J. Krantz, MD
Publikationsdatum
07.08.2017
Verlag
Springer US
Erschienen in
Journal of General Internal Medicine / Ausgabe 1/2018
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-017-4148-1

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