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Erschienen in: Archives of Women's Mental Health 1/2020

23.02.2019 | Original Article

Change of symptoms of schizophrenia across phases of menstrual cycle

verfasst von: Paramita Ray, Nikhiles Mandal, V. K. Sinha

Erschienen in: Archives of Women's Mental Health | Ausgabe 1/2020

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Abstract

The relation between schizophrenia and the menstrual cycle has always been found attractive by researchers. It is still a question of debate whether the clinical picture changes during the menstrual cycle. Our study aimed to see whether there is any change of symptoms during different phases of menstrual cycle (premenstrual, menstrual, and postmenstrual) in patients suffering from schizophrenia. Over a period of 15 months, 40 female inpatients of a tertiary care psychiatric hospital with the diagnosis of schizophrenia were assessed by applying PANSS. Rating was done up to two menstrual cycles. Total scores, positive and negative subscale scores, and general psychopathology scores of PANSS in premenstrual, menstrual, and postmenstrual phases of those patients were compared with one another by applying paired t test. Symptoms in women suffering from schizophrenia frequently vary with the different phases of menstrual cycle. The positive symptoms improved significantly only during progesterone phase. Negative symptoms and general psychopathology subscale showed improvement on estrogen phases of menstrual cycle. So optimal treatment needs to be adjusted to the individual women suffering from schizophrenia.
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Metadaten
Titel
Change of symptoms of schizophrenia across phases of menstrual cycle
verfasst von
Paramita Ray
Nikhiles Mandal
V. K. Sinha
Publikationsdatum
23.02.2019
Verlag
Springer Vienna
Erschienen in
Archives of Women's Mental Health / Ausgabe 1/2020
Print ISSN: 1434-1816
Elektronische ISSN: 1435-1102
DOI
https://doi.org/10.1007/s00737-019-0952-4

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