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01.12.2018 | Research article | Ausgabe 1/2018 Open Access

BMC Ophthalmology 1/2018

Changes in anterior chamber volume after implantation of posterior chamber phakic intraocular lens in high myopia

BMC Ophthalmology > Ausgabe 1/2018
Yi Zhu, Haobin Zhu, Yan Jia, Jibo Zhou



The present study aimed to assess changes in, and the factors that influence, anterior chamber volume (ACV) after implantable contact lens (ICL) implantation in high myopia eyes using a Pentacam.


The study sampled 26 high myopia patients (45 eyes) who were treated with ICL implantation. These patients were followed for an average of 4.28 months postoperatively. ACV was measured with a Pentacam preoperatively and at 3 months postoperatively. The data were analyzed by paired samples Wilcoxon signed-rank test. Generalized estimating equation (GEE) model adjusting within-patient intereye correlations in addition to Pearson’s and Spearman’s correlation tests were performed to determine associations.


The mean ACV was 198.33 ± 33.08 mm3 before surgery and 118.65 ± 17.70 mm3 after surgery. A significant decrease of 79.68 mm3 (40.18%) (Z = 5.841, P <  0.001) was detected. Positive correlations were found between ACV changes and ICL central vault (r = 0.528, P <  0.001) and preoperative anterior chamber depth (ACD) (r = 0.665, P <  0.001). There were positive correlations between postoperative ACV and postoperative anterior chamber angle (ACA) at 3:00 o’clock (r = 0.448, P = 0.002) and at 9:00 o’clock (r = 0.405, P = 0.006). GEE regression model showed that postoperative ACV significantly positively correlated with preoperative ACV (P = 0.002), ACD (P = 0.002) and horizontal ACA (P = 0.005) and negatively correlated with ICL central vault (P <  0.001).


Complementary to vault and ACD, ACV is a sensitive parameter with certain value of preoperative assessment and postoperative monitoring in ICL implantation.
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