Skip to main content

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

BMC Ophthalmology 1/2017

Characteristics of cases needing advanced treatment for intractable Posner–Schlossman syndrome

BMC Ophthalmology > Ausgabe 1/2017
Kazuichi Maruyama, Yuko Maruyama, Sunao Sugita, Kazuhiko Mori, Yu Yokoyama, Shiho Sanuki-Kunimatsu, Hiroko Nakagawa, Shigeru Kinoshita, Manabu Mochizuki, Toru Nakazawa
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​s12886-017-0438-y) contains supplementary material, which is available to authorized users.
Hiroko Nakagawa is deceased.



In Posner-Schlossman syndrome (PSS), which is characterized by recurrent unilateral attacks of ocular hypertension. Surgical treatment is sometimes necessary because intraocular pressure (IOP) cannot be controlled with anti-glaucoma medications. To identify the clinical features of Posner–Schlossman syndrome (PSS) indicative of the need for intraocular pressure (IOP)-controlling surgery.


This study was a retrospective case-series analysis of the clinical charts of 33 patients diagnosed with PSS, who underwent surgery to control IOP or received medication only. Various clinical factors were compared between the surgical and medication groups.


The surgical group had a higher corneal endothelial cell (CEC) density loss (p < 0.05), higher maximum IOP (p < 0.01), greater visual field loss (p < 0.01) and higher positive number for cytomegalovirus (CMV) (p < 0.001) than the non-surgical group. Eighteen of the 33 patients had a high CEC reduction ratio. Of these 18, 16 required glaucoma surgery.


PSS patients with a higher CEC reduction ratio, higher maximum IOP, greater visual field loss and higher positive number for CMV in the aqueous humor tended to be more likely to require progressive treatment, such as glaucoma surgery.
Additional file 1: The detailed data for the patients. CEC: corneal endothelial cell; IOP: intraocular pressure; VA: visual acuity; MD: mean deviation; M: male; F: female; L: left; R: right; NP: not performed; GP: Goldmann perimetry; PCR: polymerase chain reaction; CMV: cytomegalovirus; TLE: trabeculectomy; TLO: trabeculotomy; TTO; trabecutome. (XLSX 43 kb)
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2017

BMC Ophthalmology 1/2017 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

01.03.2019 | Leitlinien, Stellungnahmen und Empfehlungen | Ausgabe 4/2019

Empfehlungen bei progredienter Myopie im Kindes- und Jugendalter

Stellungnahme von DOG und BVA. Stand Dezember 2018

19.02.2019 | Refraktionsfehler | CME | Ausgabe 3/2019 Open Access