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Erschienen in: Archives of Virology 1/2012

01.01.2012 | Original Article

Characterization of novel bovine papillomavirus type 12 (BPV-12) causing epithelial papilloma

verfasst von: Wei Zhu, Jianbao Dong, Erika Shimizu, Shinichi Hatama, Koichi Kadota, Yoshitaka Goto, Takeshi Haga

Erschienen in: Archives of Virology | Ausgabe 1/2012

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Abstract

Bovine papillomavirus type 12 (BPV-12, putative type BAA1) was detected in epithelial papilloma located on the tongue of an infected cow. Then, the whole genome was sequenced, and phylogenetic analysis illustrated that it should be classified as a member of the genus Xipapillomavirus. The viral genome is 7197 base pairs in length and contains five early ORFs (E1, E2, E4, E7 and E8), three late ORFs (L1, L2 and L3), and a long control region that possesses replication regulatory elements. Meanwhile, mRNA of each gene was detected in the papilloma sample. The papilloma was identified as epithelial papilloma by histological and immunohistochemical examination. Based on the genome information and pathological properties, BAA1 was designated as BPV-12 in this study.
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Metadaten
Titel
Characterization of novel bovine papillomavirus type 12 (BPV-12) causing epithelial papilloma
verfasst von
Wei Zhu
Jianbao Dong
Erika Shimizu
Shinichi Hatama
Koichi Kadota
Yoshitaka Goto
Takeshi Haga
Publikationsdatum
01.01.2012
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 1/2012
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-011-1140-7

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