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01.05.2019 | Anaphylaxis and Drug Allergy (DA Khan and M Castells, Section Editors) | Ausgabe 5/2019

Current Allergy and Asthma Reports 5/2019

Chlorhexidine Allergy: On the Rise and Often Overlooked

Zeitschrift:
Current Allergy and Asthma Reports > Ausgabe 5/2019
Autoren:
Morten Schjørring Opstrup, Gregor Borut Ernst Jemec, Lene Heise Garvey
Wichtige Hinweise
This article is part of the Topical Collection on Anaphylaxis and Drug Allergy

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Purpose of Review

In recent years, the risk of allergy to chlorhexidine is increasingly recognised. In this review, we discuss why the allergy is so easily overlooked and point out several preventative initiatives that can minimise the risk of both chlorhexidine sensitisation and allergy development and accidental re-exposure in patients with chlorhexidine allergy. Testing for chlorhexidine allergy is also discussed.

Recent Findings

Numerous reports have been published from many different specialties. Symptoms range from mild skin symptoms to life-threatening anaphylaxis. Testing for chlorhexidine allergy is based on skin testing and in vitro testing. Recently, it was found that both skin prick testing and specific IgE have high sensitivities and specificities.

Summary

This review gives an overview of chlorhexidine allergy with a special focus on preventative initiatives and testing.

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