Chordoma of the Head and Neck: A Review
- 04.10.2017
- Invited Review
- Verfasst von
- Jason K. Wasserman
- Denis Gravel
- Bibianna Purgina
- Erschienen in
- Head and Neck Pathology | Ausgabe 2/2018
Abstract
Chordoma is a rare malignant bone tumor that can arise anywhere along the central neural axis and many involve head and neck sites, most commonly the skull base. The relative rarity of these tumors, combined with the complex anatomy of the head and neck, pose diagnostic challenges to pathologists. This article describes the pertinent clinical, pathologic, and molecular features of chordomas and describes how these features can be used to aid in formulating a differential diagnosis. Emphasis is placed on key diagnostic pitfalls and the importance of incorporating immunohistochemical information into the diagnosis.
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- Titel
- Chordoma of the Head and Neck: A Review
- Verfasst von
-
Jason K. Wasserman
Denis Gravel
Bibianna Purgina
- Publikationsdatum
- 04.10.2017
- Verlag
- Springer US
- Erschienen in
-
Head and Neck Pathology / Ausgabe 2/2018
Elektronische ISSN: 1936-0568 - DOI
- https://doi.org/10.1007/s12105-017-0860-8
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