Skip to main content
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 11/2020

29.08.2020 | Retinal Disorders

Choroidal vascularity index and choriocapillary changes in retinal vein occlusions

verfasst von: Yavuz Kemal Aribas, Ahmet M. Hondur, Tongalp H. Tezel

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 11/2020

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To evaluate the changes in the choroidal structure in the setting of retinal vein occlusion (RVO).

Methods

Changes in the structure of the choroid were studied in sixty-four eyes with unilateral central or branch RVO using optical coherence tomography (OCT) with enhanced depth imaging and OCT-angiography (OCT-A). Choroidal vascularity index (CVI), Haller layer/choroidal thickness (H/C) ratio, and choriocapillaris flow density were used to compare the structural characteristics of the choroid with fellow eyes and the eyes of thirty-four age-, gender-, and systemic co-morbidity–matched controls.

Results

Eyes with RVO had a higher H/C ratio but a lower choriocapillaris flow density compared to both fellow and control eyes (p < 0.001). CVI was significantly lower in both eyes of the patients with RVO compared with control eyes (p < 0.05) with a more robust decrease in the eye that had developed RVO (p < 0.001). The H/C ratio (r = 0.303 p < 0.001), CVI (r = − 0.268, p = 0.001), and choriocapillaris flow density (r = − 0.237, p = 0.003) were all correlated with logMAR visual acuity, and other clinical features.

Conclusion

Retinal vein occlusions alter the hemodynamic properties of the choroid leading to structural changes. These changes may be secondary to a compensatory mechanism to supply oxygen to hypoxic retina.
Literatur
5.
Zurück zum Zitat Khodabandeh A, Shahraki K, Roohipoor R, Riazi-Esfahani H, Yaseri M, Faghihi H, Bazvand F (2018) Quantitative measurement of vascular density and flow using optical coherence tomography angiography (OCTA) in patients with central retinal vein occlusion: can OCTA help in distinguishing ischemic from non-ischemic type? Int J Retin Vitreous 4:47–47. https://doi.org/10.1186/s40942-018-0152-9CrossRef Khodabandeh A, Shahraki K, Roohipoor R, Riazi-Esfahani H, Yaseri M, Faghihi H, Bazvand F (2018) Quantitative measurement of vascular density and flow using optical coherence tomography angiography (OCTA) in patients with central retinal vein occlusion: can OCTA help in distinguishing ischemic from non-ischemic type? Int J Retin Vitreous 4:47–47. https://​doi.​org/​10.​1186/​s40942-018-0152-9CrossRef
6.
Zurück zum Zitat Mastropasqua R, Toto L, Di Antonio L, Borrelli E, Senatore A, Di Nicola M, Di Martino G, Ciancaglini M, Carpineto P (2017) Optical coherence tomography angiography microvascular findings in macular edema due to central and branch retinal vein occlusions. Sci Rep 7:40763. https://doi.org/10.1038/srep40763CrossRefPubMed Mastropasqua R, Toto L, Di Antonio L, Borrelli E, Senatore A, Di Nicola M, Di Martino G, Ciancaglini M, Carpineto P (2017) Optical coherence tomography angiography microvascular findings in macular edema due to central and branch retinal vein occlusions. Sci Rep 7:40763. https://​doi.​org/​10.​1038/​srep40763CrossRefPubMed
10.
Zurück zum Zitat Sonoda S, Sakamoto T, Yamashita T, Shirasawa M, Uchino E, Terasaki H, Tomita M (2014) Choroidal structure in normal eyes and after photodynamic therapy determined by Binarization of optical coherence tomographic ImagesBinarization of OCT on choroid. Invest Ophthalmol Vis Sci 55(6):3893–3899. https://doi.org/10.1167/iovs.14-14447CrossRefPubMed Sonoda S, Sakamoto T, Yamashita T, Shirasawa M, Uchino E, Terasaki H, Tomita M (2014) Choroidal structure in normal eyes and after photodynamic therapy determined by Binarization of optical coherence tomographic ImagesBinarization of OCT on choroid. Invest Ophthalmol Vis Sci 55(6):3893–3899. https://​doi.​org/​10.​1167/​iovs.​14-14447CrossRefPubMed
12.
Zurück zum Zitat Shao Z, Dorfman AL, Seshadri S, Djavari M, Kermorvant-Duchemin E, Sennlaub F, Blais M, Polosa A, Varma DR, Joyal JS, Lachapelle P, Hardy P, Sitaras N, Picard E, Mancini J, Sapieha P, Chemtob S (2011) Choroidal involution is a key component of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 52(9):6238–6248. https://doi.org/10.1167/iovs.10-6742CrossRefPubMed Shao Z, Dorfman AL, Seshadri S, Djavari M, Kermorvant-Duchemin E, Sennlaub F, Blais M, Polosa A, Varma DR, Joyal JS, Lachapelle P, Hardy P, Sitaras N, Picard E, Mancini J, Sapieha P, Chemtob S (2011) Choroidal involution is a key component of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 52(9):6238–6248. https://​doi.​org/​10.​1167/​iovs.​10-6742CrossRefPubMed
20.
Zurück zum Zitat Schroder K, Ackermann P, Brachert M, Bairov S, Geerling G, Guthoff R (2016) Does OCT morphology provide indications for prognosis of visual acuity after venous occlusion? : SD-OCT analysis in retinal vein occlusion before and after resolution of initial macular edema. Ophthalmologe 113(6):500–506. https://doi.org/10.1007/s00347-016-0234-8CrossRefPubMed Schroder K, Ackermann P, Brachert M, Bairov S, Geerling G, Guthoff R (2016) Does OCT morphology provide indications for prognosis of visual acuity after venous occlusion? : SD-OCT analysis in retinal vein occlusion before and after resolution of initial macular edema. Ophthalmologe 113(6):500–506. https://​doi.​org/​10.​1007/​s00347-016-0234-8CrossRefPubMed
21.
Zurück zum Zitat Costanzo E, Parravano M, Gilardi M, Cavalleri M, Sacconi R, Aragona E, Varano M, Bandello F, Querques G (2019) Microvascular retinal and choroidal changes in retinal vein occlusion analyzed by two different optical coherence tomography angiography devices. Ophthalmologica 242(1):8–15. https://doi.org/10.1159/000496195CrossRefPubMed Costanzo E, Parravano M, Gilardi M, Cavalleri M, Sacconi R, Aragona E, Varano M, Bandello F, Querques G (2019) Microvascular retinal and choroidal changes in retinal vein occlusion analyzed by two different optical coherence tomography angiography devices. Ophthalmologica 242(1):8–15. https://​doi.​org/​10.​1159/​000496195CrossRefPubMed
Metadaten
Titel
Choroidal vascularity index and choriocapillary changes in retinal vein occlusions
verfasst von
Yavuz Kemal Aribas
Ahmet M. Hondur
Tongalp H. Tezel
Publikationsdatum
29.08.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 11/2020
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-020-04886-3

Weitere Artikel der Ausgabe 11/2020

Graefe's Archive for Clinical and Experimental Ophthalmology 11/2020 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Open Access 22.02.2024 | Peeling | Originalien

Selektive Vitalfarbstoffe in der Makulachirurgie

Erhöhen sie die Wahrscheinlichkeit der intraoperativen ILM-Identifizierung auch bei einem erfahrenen Operateur?

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.