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Erschienen in:
29.11.2021 | Sleep Breathing Physiology and Disorders • Original Article
Choroidal vascularity index in obstructive sleep apnea syndrome
Erschienen in: Sleep and Breathing | Ausgabe 4/2022
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Background
There is growing evidence supporting an association between obstructive sleep apnea syndrome (OSAS) and systemic vascular disorders. However, the data on choroidal microvasculature are limited. In recent years, choroidal thickness (CT) and choroidal vascularity index (CVI) have been of considerable interest as objective markers of choroidal vascularity. We hypothesized that the imbalance of vascular regulation in OSAS may adversely affect the CT and CVI and may help to assess the vascular risk in these patients.
Purpose
This study aimed to evaluate the choroidal morphology in patients with OSAS.
Materials and methods
Patients with moderate OSAS were included to this study. The subfoveal, nasal, and temporal CT were calculated. The choroidal area (CA) was binarized to the luminal area (LA) and stromal area (SA) using ImageJ software. The CVI was calculated as the proportion of the LA to the total CA.
Results
Of 40 eyes of 40 patients, the mean subfoveal CT was significantly decreased in the OSAS group in comparison to the controls (p = 0.032). The mean CA, LA, and SA were decreased in the OSAS group compared with the controls, but the differences did not reach a statistical significance (p = 0.132, p = 0.104, and p = 0.184, respectively). The CVI was not significantly changed in patients with OSAS (p = 1.000).
Conclusion
Unlike CT, there were no significant differences in choroidal structural parameters and CVI in patients with OSAS.