CLIPPERS is a recently described rare inflammatory central nervous system (CNS) disease, which is considered as a T-cell-mediated cause of inflammatory lesions affecting predominantly the brainstem and often the basal ganglia, cerebellum and spinal cord, presenting as punctate patchy contrast enhancement on MRI images. The usual clinical features of CLIPPERS manifest in a subacute manner and include diplopia, dysarthria, facial paresthesias and gait ataxia. Its dramatic response and dependence on corticosteroids are also remarkable, as a hallmark of the disease [
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