Skip to main content
Erschienen in: Acta Diabetologica 6/2019

13.02.2019 | Short Communication

Circulating miRNA-375 levels are increased in autoantibodies-positive first-degree relatives of type 1 diabetes patients

verfasst von: L. Bertoccini, F. Sentinelli, M. Incani, D. Bailetti, F. A. Cimini, I. Barchetta, A. Lenzi, M. G. Cavallo, E. Cossu, M. G. Baroni

Erschienen in: Acta Diabetologica | Ausgabe 6/2019

Einloggen, um Zugang zu erhalten

Excerpt

Growing evidence suggests that microRNAs (miRNAs) play a key role in immune system functions as well as in beta-cell metabolism, proliferation, and apoptosis, all processes involved in the pathogenesis of type 1 diabetes (T1D) [1]. …
Literatur
1.
Zurück zum Zitat Assmann TS, Recamonde-Mendoza M, De Souza BM, Crispim D (2017) MicroRNA expression profiles and type 1 diabetes mellitus: systematic review and bioinformatics analysis. Endocr Connect 6:773–790CrossRefPubMedPubMedCentral Assmann TS, Recamonde-Mendoza M, De Souza BM, Crispim D (2017) MicroRNA expression profiles and type 1 diabetes mellitus: systematic review and bioinformatics analysis. Endocr Connect 6:773–790CrossRefPubMedPubMedCentral
2.
Zurück zum Zitat Marchand L, Jalabert A, Meugnier E et al (2016) miRNA-375 a sensor of glucotoxicity is altered in the serum of children with newly diagnosed type 1 diabetes. J Diabetes Res 2016:1869082CrossRefPubMedPubMedCentral Marchand L, Jalabert A, Meugnier E et al (2016) miRNA-375 a sensor of glucotoxicity is altered in the serum of children with newly diagnosed type 1 diabetes. J Diabetes Res 2016:1869082CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Zheng Y, Wang Z, Zhou Z (2017) miRNAs: novel regulators of autoimmunity-mediated pancreatic β-cell destruction in type 1 diabetes. Cell Mol Immunol 14:488–496CrossRefPubMedPubMedCentral Zheng Y, Wang Z, Zhou Z (2017) miRNAs: novel regulators of autoimmunity-mediated pancreatic β-cell destruction in type 1 diabetes. Cell Mol Immunol 14:488–496CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Sims EK, Evans-Molina C, Tersey SA, Eizirik DL, Mirmira RG (2018) Biomarkers of islet beta cell stress and death in type 1 diabetes. Diabetologia 61:2259–2265CrossRefPubMed Sims EK, Evans-Molina C, Tersey SA, Eizirik DL, Mirmira RG (2018) Biomarkers of islet beta cell stress and death in type 1 diabetes. Diabetologia 61:2259–2265CrossRefPubMed
5.
Zurück zum Zitat Incani M, Serafini C, Satta C et al (2017) High prevalence of diabetes-specific autoimmunity in first-degree relatives of Sardinian patients with type 1 diabetes. Diabetes Metab Res Rev 33(3):e2864CrossRef Incani M, Serafini C, Satta C et al (2017) High prevalence of diabetes-specific autoimmunity in first-degree relatives of Sardinian patients with type 1 diabetes. Diabetes Metab Res Rev 33(3):e2864CrossRef
Metadaten
Titel
Circulating miRNA-375 levels are increased in autoantibodies-positive first-degree relatives of type 1 diabetes patients
verfasst von
L. Bertoccini
F. Sentinelli
M. Incani
D. Bailetti
F. A. Cimini
I. Barchetta
A. Lenzi
M. G. Cavallo
E. Cossu
M. G. Baroni
Publikationsdatum
13.02.2019
Verlag
Springer Milan
Erschienen in
Acta Diabetologica / Ausgabe 6/2019
Print ISSN: 0940-5429
Elektronische ISSN: 1432-5233
DOI
https://doi.org/10.1007/s00592-019-01297-7

Weitere Artikel der Ausgabe 6/2019

Acta Diabetologica 6/2019 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.