Skip to main content
Erschienen in: Journal of General Internal Medicine 12/2018

24.09.2018 | Original Research

Circumstances Surrounding High-risk Sexual Experiences Among Primary Care Patients Living With and Without HIV

verfasst von: Rob J. Fredericksen, PhD, MPH, M. Walcott, PhD, F. M. Yang, PhD, L. E. Gibbons, PhD, E. Fitzsimmons, BA, S. Brown, MPH, MSW, K. H. Mayer, MD, T. C. Edwards, PhD, S. Loo, MSc, C. Gutierrez, BA, E. Paez, MsC, L. Dant, MPH, W. C. Mathews, MD, M. J. Mugavero, MD, D. L. Patrick, PhD, P. K. Crane, MD, H. M. Crane, MD

Erschienen in: Journal of General Internal Medicine | Ausgabe 12/2018

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Rates of sexually transmitted infection (STI) are rising in the USA, yet STI risk remains under-addressed by providers, even in HIV care, and with high-risk patients. We interviewed primary care patients living with and without HIV regarding circumstances surrounding sexual risk behavior to identify opportunities for providers to address and reduce STI risk.

Methods

We conducted semi-structured 1:1 interviews with patients living with and without HIV reporting ≥ 1 sex partner and varying STI exposure risk in the past 12 months from four geographically diverse US HIV and primary care clinics. We audio-recorded, transcribed, and coded interviews by circumstance type, using double-coding to ensure inter-coder reliability. We used Fisher’s exact and T tests to determine associations with demographic/risk factors.

Results

Patients (n = 91) identified a mean of 3 of 11 circumstances. These included substance use (54%), desire for physical/emotional intimacy (48%), lack of HIV/STI status disclosure (44%), psychological drivers (i.e., coping, depression; 38%), personal dislike of condoms (22%), partner condom dislike/refusal (19%), receiving payment for sex (13%), and condom unavailability (9%). Higher proportions of those who were high STI-exposure risk patients, defined as those with ≥ 2 sex partners in the past 3 months reporting never or sometimes using condoms, reported disliking condoms (p = .006); higher proportions of the high-risk and moderate-risk (≥ 2 partners and condom use “most of the time”) groups reported substance use as a circumstance (p = .04).

Conclusion

Circumstances surrounding perceived STI exposure risk were diverse, often overlapping, and dependent on internal, environmental, and partner-related factors and inadequate communication. Meaningful care-based interventions regarding HIV/STI transmission behavior must address the diversity and interplay of these factors.
Literatur
1.
Zurück zum Zitat Centers for Disease Control fact sheet: reported STD’s in the United States. 2016. Centers for Disease Control fact sheet: reported STD’s in the United States. 2016.
2.
Zurück zum Zitat Wimberly YH, Hogben M, Moore-Ruffin J, Moore SE, Fry-Johnson Y. Sexual history-taking among primary care physicians. J Natl Med Assoc. 2006,98:1924–1929.PubMedPubMedCentral Wimberly YH, Hogben M, Moore-Ruffin J, Moore SE, Fry-Johnson Y. Sexual history-taking among primary care physicians. J Natl Med Assoc. 2006,98:1924–1929.PubMedPubMedCentral
3.
Zurück zum Zitat Talking with patients about sexuality and sexual health. In: Clinical fact sheets. Washington, DC: Association of Reproductive Health Professionals; 2010. Talking with patients about sexuality and sexual health. In: Clinical fact sheets. Washington, DC: Association of Reproductive Health Professionals; 2010.
4.
Zurück zum Zitat Glaude-Hosch JA, Smith ML, Heckman TG, Miles TP, Olubajo BA, Ory MG. Sexual Behaviors, Healthcare Interactions, and HIV-Related Perceptions Among Adults Age 60 Years and Older: An Investigation by Race/Ethnicity. Curr HIV Res. 2015,13:359–368.CrossRef Glaude-Hosch JA, Smith ML, Heckman TG, Miles TP, Olubajo BA, Ory MG. Sexual Behaviors, Healthcare Interactions, and HIV-Related Perceptions Among Adults Age 60 Years and Older: An Investigation by Race/Ethnicity. Curr HIV Res. 2015,13:359–368.CrossRef
5.
Zurück zum Zitat Savasta AM. HIV: associated transmission risks in older adults--an integrative review of the literature. J Assoc Nurses AIDS Care. 2004,15:50–59.CrossRef Savasta AM. HIV: associated transmission risks in older adults--an integrative review of the literature. J Assoc Nurses AIDS Care. 2004,15:50–59.CrossRef
6.
Zurück zum Zitat Fredericksen R, Crane PK, Feldman BJ, Tufano J, Harrington RD, Dhanireddy S , et al. Impact of same-day pre-visit electronic patient-reported outcome (PRO) collection on provider assessment of sexual risk and other behaviors of HIV-infected patients in routine clinical care. In: American Public Health Association 139th Annual Meeting. Washington, D.C.; 2011. Fredericksen R, Crane PK, Feldman BJ, Tufano J, Harrington RD, Dhanireddy S , et al. Impact of same-day pre-visit electronic patient-reported outcome (PRO) collection on provider assessment of sexual risk and other behaviors of HIV-infected patients in routine clinical care. In: American Public Health Association 139th Annual Meeting. Washington, D.C.; 2011.
7.
Zurück zum Zitat Gardner LI, Metsch L, Strathdee SA, del Rio C, Mahoney P, Holmberg SD , et al. Frequency of discussing HIV prevention and care topics with patients with HIV: influence of physician gender, race/ethnicity, and practice characteristics. Gend Med. 2008,5:259–269.CrossRef Gardner LI, Metsch L, Strathdee SA, del Rio C, Mahoney P, Holmberg SD , et al. Frequency of discussing HIV prevention and care topics with patients with HIV: influence of physician gender, race/ethnicity, and practice characteristics. Gend Med. 2008,5:259–269.CrossRef
8.
Zurück zum Zitat Marquez C, Mitchell SJ, Hare CB, John M, Klausner JD. Methamphetamine use, sexual activity, patient-provider communication, and medication adherence among HIV-infected patients in care, San Francisco 2004-2006. AIDS Care. 2009,21:575–582.CrossRef Marquez C, Mitchell SJ, Hare CB, John M, Klausner JD. Methamphetamine use, sexual activity, patient-provider communication, and medication adherence among HIV-infected patients in care, San Francisco 2004-2006. AIDS Care. 2009,21:575–582.CrossRef
9.
Zurück zum Zitat Laws MB, Bradshaw YS, Safren SA, Beach MC, Lee Y, Rogers W , et al. Discussion of sexual risk behavior in HIV care is infrequent and appears ineffectual: a mixed methods study. AIDS Behav. 2011,15:812–822.CrossRef Laws MB, Bradshaw YS, Safren SA, Beach MC, Lee Y, Rogers W , et al. Discussion of sexual risk behavior in HIV care is infrequent and appears ineffectual: a mixed methods study. AIDS Behav. 2011,15:812–822.CrossRef
10.
Zurück zum Zitat Drainoni ML, Dekker D, Lee-Hood E, Boehmer U, Relf M. HIV medical care provider practices for reducing high-risk sexual behavior: results of a qualitative study. AIDS Patient Care STDS. 2009,23:347–356.CrossRef Drainoni ML, Dekker D, Lee-Hood E, Boehmer U, Relf M. HIV medical care provider practices for reducing high-risk sexual behavior: results of a qualitative study. AIDS Patient Care STDS. 2009,23:347–356.CrossRef
11.
Zurück zum Zitat Wolitski RJ, Fenton KA. Sexual health, HIV, and sexually transmitted infections among gay, bisexual, and other men who have sex with men in the United States. AIDS Behav. 2011,15 Suppl 1:S9–17.CrossRef Wolitski RJ, Fenton KA. Sexual health, HIV, and sexually transmitted infections among gay, bisexual, and other men who have sex with men in the United States. AIDS Behav. 2011,15 Suppl 1:S9–17.CrossRef
12.
Zurück zum Zitat van Liere GA, Hoebe CJ, Niekamp AM, Koedijk FD, Dukers-Muijrers NH. Standard symptom- and sexual history-based testing misses anorectal Chlamydia trachomatis and neisseria gonorrhoeae infections in swingers and men who have sex with men. Sex Transm Dis. 2013,40:285–289.CrossRef van Liere GA, Hoebe CJ, Niekamp AM, Koedijk FD, Dukers-Muijrers NH. Standard symptom- and sexual history-based testing misses anorectal Chlamydia trachomatis and neisseria gonorrhoeae infections in swingers and men who have sex with men. Sex Transm Dis. 2013,40:285–289.CrossRef
13.
Zurück zum Zitat Morin SF, Koester KA, Steward WT, Maiorana A, McLaughlin M, Myers JJ , et al. Missed opportunities: prevention with HIV-infected patients in clinical care settings. J Acquir Immune Defic Syndr. 2004,36:960–966.CrossRef Morin SF, Koester KA, Steward WT, Maiorana A, McLaughlin M, Myers JJ , et al. Missed opportunities: prevention with HIV-infected patients in clinical care settings. J Acquir Immune Defic Syndr. 2004,36:960–966.CrossRef
14.
Zurück zum Zitat Burd ID, Nevadunsky N, Bachmann G. Impact of physician gender on sexual history taking in a multispecialty practice. J Sex Med. 2006,3:194–200.CrossRef Burd ID, Nevadunsky N, Bachmann G. Impact of physician gender on sexual history taking in a multispecialty practice. J Sex Med. 2006,3:194–200.CrossRef
15.
Zurück zum Zitat Politi MC, Clark MA, Armstrong G, McGarry KA, Sciamanna CN. Patient-provider communication about sexual health among unmarried middle-aged and older women. J Gen Intern Med. 2009,24:511–516.CrossRef Politi MC, Clark MA, Armstrong G, McGarry KA, Sciamanna CN. Patient-provider communication about sexual health among unmarried middle-aged and older women. J Gen Intern Med. 2009,24:511–516.CrossRef
16.
Zurück zum Zitat Hayes V, Blondeau W, Bing-You RG. Assessment of Medical Student and Resident/Fellow Knowledge, Comfort, and Training With Sexual History Taking in LGBTQ Patients. Fam Med. 2015,47:383–387.PubMed Hayes V, Blondeau W, Bing-You RG. Assessment of Medical Student and Resident/Fellow Knowledge, Comfort, and Training With Sexual History Taking in LGBTQ Patients. Fam Med. 2015,47:383–387.PubMed
17.
Zurück zum Zitat Lurie N, Margolis K, McGovern PG, Mink P. Physician self-report of comfort and skill in providing preventive care to patients of the opposite sex. Arch Fam Med. 1998,7:134–137.CrossRef Lurie N, Margolis K, McGovern PG, Mink P. Physician self-report of comfort and skill in providing preventive care to patients of the opposite sex. Arch Fam Med. 1998,7:134–137.CrossRef
18.
Zurück zum Zitat Tao G, Irwin KL, Kassler WJ. Missed opportunities to assess sexually transmitted diseases in U.S. adults during routine medical checkups. Am J Prev Med. 2000,18:109–114.CrossRef Tao G, Irwin KL, Kassler WJ. Missed opportunities to assess sexually transmitted diseases in U.S. adults during routine medical checkups. Am J Prev Med. 2000,18:109–114.CrossRef
19.
Zurück zum Zitat Meanley S, Gale A, Harmell C, Jadwin-Cakmak L, Pingel E, Bauermeister JA. The role of provider interactions on comprehensive sexual healthcare among young men who have sex with men. AIDS Educ Prev. 2015,27:15–26.CrossRef Meanley S, Gale A, Harmell C, Jadwin-Cakmak L, Pingel E, Bauermeister JA. The role of provider interactions on comprehensive sexual healthcare among young men who have sex with men. AIDS Educ Prev. 2015,27:15–26.CrossRef
20.
Zurück zum Zitat Fisher JD, Fisher WA, Cornman DH, Amico RK, Bryan A, Friedland GH. Clinician-delivered intervention during routine clinical care reduces unprotected sexual behavior among HIV-infected patients. J Acquir Immune Defic Syndr. 2006,41:44–52.CrossRef Fisher JD, Fisher WA, Cornman DH, Amico RK, Bryan A, Friedland GH. Clinician-delivered intervention during routine clinical care reduces unprotected sexual behavior among HIV-infected patients. J Acquir Immune Defic Syndr. 2006,41:44–52.CrossRef
21.
Zurück zum Zitat Patel P, Bush T, Mayer K, Milam J, Richardson J, Hammer J, et al. Routine brief risk-reduction counseling with biannual STD testing reduces STD incidence among HIV-infected men who have sex with men in care. Sex Transm Dis. 2012,39:470–474.CrossRef Patel P, Bush T, Mayer K, Milam J, Richardson J, Hammer J, et al. Routine brief risk-reduction counseling with biannual STD testing reduces STD incidence among HIV-infected men who have sex with men in care. Sex Transm Dis. 2012,39:470–474.CrossRef
22.
Zurück zum Zitat Rose CD, Courtenay-Quirk C, Knight K, Shade SB, Vittinghoff E, Gomez C , et al. HIV intervention for providers study: a randomized controlled trial of a clinician-delivered HIV risk-reduction intervention for HIV-positive people. J Acquir Immune Defic Syndr. 2010,55:572–581.CrossRef Rose CD, Courtenay-Quirk C, Knight K, Shade SB, Vittinghoff E, Gomez C , et al. HIV intervention for providers study: a randomized controlled trial of a clinician-delivered HIV risk-reduction intervention for HIV-positive people. J Acquir Immune Defic Syndr. 2010,55:572–581.CrossRef
23.
Zurück zum Zitat Gardner LI, Marks G, O’Daniels CM, Wilson TE, Golin C, Wright J , et al. Implementation and evaluation of a clinic-based behavioral intervention: positive steps for patients with HIV. AIDS Patient Care STDS. 2008,22:627–635.CrossRef Gardner LI, Marks G, O’Daniels CM, Wilson TE, Golin C, Wright J , et al. Implementation and evaluation of a clinic-based behavioral intervention: positive steps for patients with HIV. AIDS Patient Care STDS. 2008,22:627–635.CrossRef
24.
Zurück zum Zitat Kamb ML, Fishbein M, Douglas JM, Jr., Rhodes F, Rogers J, Bolan G , et al. Efficacy of risk-reduction counseling to prevent human immunodeficiency virus and sexually transmitted diseases: a randomized controlled trial. Project RESPECT Study Group. JAMA. 1998,280:1161–1167. Kamb ML, Fishbein M, Douglas JM, Jr., Rhodes F, Rogers J, Bolan G , et al. Efficacy of risk-reduction counseling to prevent human immunodeficiency virus and sexually transmitted diseases: a randomized controlled trial. Project RESPECT Study Group. JAMA. 1998,280:1161–1167.
26.
Zurück zum Zitat Chen X, Murphy DA, Naar-King S, Parsons JT. Adolescent Medicine Trials Network for HIVAI. A clinic-based motivational intervention improves condom use among subgroups of youth living with HIV. J Adolesc Health. 2011,49:193–198.CrossRef Chen X, Murphy DA, Naar-King S, Parsons JT. Adolescent Medicine Trials Network for HIVAI. A clinic-based motivational intervention improves condom use among subgroups of youth living with HIV. J Adolesc Health. 2011,49:193–198.CrossRef
27.
Zurück zum Zitat Velasquez MM, von Sternberg K, Johnson DH, Green C, Carbonari JP, Parsons JT. Reducing sexual risk behaviors and alcohol use among HIV-positive men who have sex with men: a randomized clinical trial. J Consult Clin Psychol. 2009,77:657–667.CrossRef Velasquez MM, von Sternberg K, Johnson DH, Green C, Carbonari JP, Parsons JT. Reducing sexual risk behaviors and alcohol use among HIV-positive men who have sex with men: a randomized clinical trial. J Consult Clin Psychol. 2009,77:657–667.CrossRef
28.
Zurück zum Zitat Murphy DA, Brecht ML, Herbeck DM, Huang D. Trajectories of HIV risk behavior from age 15 to 25 in the national longitudinal survey of youth sample. J Youth Adolesc. 2009,38:1226–1239.CrossRef Murphy DA, Brecht ML, Herbeck DM, Huang D. Trajectories of HIV risk behavior from age 15 to 25 in the national longitudinal survey of youth sample. J Youth Adolesc. 2009,38:1226–1239.CrossRef
29.
Zurück zum Zitat Dedoose version 5.0.11, Web application for managing, analyzing, and presenting qualitative and mixed method research data. Los Angeles, CA: Sociocultural Research Consultants LLC; 2014. Dedoose version 5.0.11, Web application for managing, analyzing, and presenting qualitative and mixed method research data. Los Angeles, CA: Sociocultural Research Consultants LLC; 2014.
30.
Zurück zum Zitat Reback CJ, Larkins S, Shoptaw S. Changes in the meaning of sexual risk behaviors among gay and bisexual male methamphetamine abusers before and after drug treatment. AIDS Behav. 2004,8:87–98.CrossRef Reback CJ, Larkins S, Shoptaw S. Changes in the meaning of sexual risk behaviors among gay and bisexual male methamphetamine abusers before and after drug treatment. AIDS Behav. 2004,8:87–98.CrossRef
31.
Zurück zum Zitat Yi H, Sandfort TG, Shidlo A. Effects of disengagement coping with HIV risk on unprotected sex among HIV-negative gay men in New York City. Health Psychol. 2010,29:205–214.CrossRef Yi H, Sandfort TG, Shidlo A. Effects of disengagement coping with HIV risk on unprotected sex among HIV-negative gay men in New York City. Health Psychol. 2010,29:205–214.CrossRef
32.
Zurück zum Zitat Kelly BC, Bimbi DS, Izienicki H, Parsons JT. Stress and coping among HIV-positive barebackers. AIDS Behav. 2009,13:792–797.CrossRef Kelly BC, Bimbi DS, Izienicki H, Parsons JT. Stress and coping among HIV-positive barebackers. AIDS Behav. 2009,13:792–797.CrossRef
33.
Zurück zum Zitat Martin JI, Pryce JG, Leeper JD. Avoidance coping and HIV risk behavior among gay men. Health Soc Work. 2005,30:193–201.CrossRef Martin JI, Pryce JG, Leeper JD. Avoidance coping and HIV risk behavior among gay men. Health Soc Work. 2005,30:193–201.CrossRef
34.
Zurück zum Zitat Gowda C, Coppock D, Brickman C, Shaw PA, Gross R. Determinants of HIV Transmission Risk Among HIV-Infected Persons Engaged in Care. AIDS Educ Prev. 2016,28:440–452.CrossRef Gowda C, Coppock D, Brickman C, Shaw PA, Gross R. Determinants of HIV Transmission Risk Among HIV-Infected Persons Engaged in Care. AIDS Educ Prev. 2016,28:440–452.CrossRef
35.
Zurück zum Zitat Alvy LM, McKirnan DJ, Mansergh G, Koblin B, Colfax GN, Flores SA, et al. Depression is associated with sexual risk among men who have sex with men, but is mediated by cognitive escape and self-efficacy. AIDS Behav. 2011,15:1171–1179.CrossRef Alvy LM, McKirnan DJ, Mansergh G, Koblin B, Colfax GN, Flores SA, et al. Depression is associated with sexual risk among men who have sex with men, but is mediated by cognitive escape and self-efficacy. AIDS Behav. 2011,15:1171–1179.CrossRef
36.
Zurück zum Zitat Herbst JH, Sherba RT, Crepaz N, Deluca JB, Zohrabyan L, Stall RD, et al. A meta-analytic review of HIV behavioral interventions for reducing sexual risk behavior of men who have sex with men. J Acquir Immune Defic Syndr. 2005,39:228–241.PubMed Herbst JH, Sherba RT, Crepaz N, Deluca JB, Zohrabyan L, Stall RD, et al. A meta-analytic review of HIV behavioral interventions for reducing sexual risk behavior of men who have sex with men. J Acquir Immune Defic Syndr. 2005,39:228–241.PubMed
37.
Zurück zum Zitat Broeckaert L, Challacombe L. Disclosure programming: a review of the evidence. Prevention in Focus. 2016. Broeckaert L, Challacombe L. Disclosure programming: a review of the evidence. Prevention in Focus. 2016.
38.
Zurück zum Zitat Wolitski RJ, Gomez CA, Parsons JT. Effects of a peer-led behavioral intervention to reduce HIV transmission and promote serostatus disclosure among HIV-seropositive gay and bisexual men. AIDS. 2005,19 Suppl 1:S99–109.CrossRef Wolitski RJ, Gomez CA, Parsons JT. Effects of a peer-led behavioral intervention to reduce HIV transmission and promote serostatus disclosure among HIV-seropositive gay and bisexual men. AIDS. 2005,19 Suppl 1:S99–109.CrossRef
39.
Zurück zum Zitat Carballo-Dieguez A, Ventuneac A, Dowsett GW, Balan I, Bauermeister J, Remien RH, et al. Sexual pleasure and intimacy among men who engage in “bareback sex”. AIDS Behav. 2011,15 Suppl 1:S57–65.CrossRef Carballo-Dieguez A, Ventuneac A, Dowsett GW, Balan I, Bauermeister J, Remien RH, et al. Sexual pleasure and intimacy among men who engage in “bareback sex”. AIDS Behav. 2011,15 Suppl 1:S57–65.CrossRef
40.
Zurück zum Zitat Balan IC, Carballo-Dieguez A, Ventuneac A, Remien RH. Intentional condomless anal intercourse among Latino MSM who meet sexual partners on the Internet. AIDS Educ Prev. 2009,21:14–24.CrossRef Balan IC, Carballo-Dieguez A, Ventuneac A, Remien RH. Intentional condomless anal intercourse among Latino MSM who meet sexual partners on the Internet. AIDS Educ Prev. 2009,21:14–24.CrossRef
41.
Zurück zum Zitat Mallory C. African American women’s experience of infection with HIV in the rural southeastern United States. J Assoc Nurses AIDS Care. 2008,19:28–36.CrossRef Mallory C. African American women’s experience of infection with HIV in the rural southeastern United States. J Assoc Nurses AIDS Care. 2008,19:28–36.CrossRef
42.
Zurück zum Zitat Chariyeva Z, Golin CE, Earp JA, Suchindran C. Does motivational interviewing counseling time influence HIV-positive persons’ self-efficacy to practice safer sex?, Patient Educ Couns. 2012,87:101–107.CrossRef Chariyeva Z, Golin CE, Earp JA, Suchindran C. Does motivational interviewing counseling time influence HIV-positive persons’ self-efficacy to practice safer sex?, Patient Educ Couns. 2012,87:101–107.CrossRef
43.
Zurück zum Zitat Carey MP, Braaten LS, Maisto SA, Gleason JR, Forsyth AD, Durant LE, et al. Using information, motivational enhancement, and skills training to reduce the risk of HIV infection for low-income urban women: a second randomized clinical trial. Health Psychol. 2000,19:3–11.CrossRef Carey MP, Braaten LS, Maisto SA, Gleason JR, Forsyth AD, Durant LE, et al. Using information, motivational enhancement, and skills training to reduce the risk of HIV infection for low-income urban women: a second randomized clinical trial. Health Psychol. 2000,19:3–11.CrossRef
44.
Zurück zum Zitat Kiene SM, Barta WD. A brief individualized computer-delivered sexual risk reduction intervention increases HIV/AIDS preventive behavior. J Adolesc Health. 2006,39:404–410.CrossRef Kiene SM, Barta WD. A brief individualized computer-delivered sexual risk reduction intervention increases HIV/AIDS preventive behavior. J Adolesc Health. 2006,39:404–410.CrossRef
Metadaten
Titel
Circumstances Surrounding High-risk Sexual Experiences Among Primary Care Patients Living With and Without HIV
verfasst von
Rob J. Fredericksen, PhD, MPH
M. Walcott, PhD
F. M. Yang, PhD
L. E. Gibbons, PhD
E. Fitzsimmons, BA
S. Brown, MPH, MSW
K. H. Mayer, MD
T. C. Edwards, PhD
S. Loo, MSc
C. Gutierrez, BA
E. Paez, MsC
L. Dant, MPH
W. C. Mathews, MD
M. J. Mugavero, MD
D. L. Patrick, PhD
P. K. Crane, MD
H. M. Crane, MD
Publikationsdatum
24.09.2018
Verlag
Springer US
Erschienen in
Journal of General Internal Medicine / Ausgabe 12/2018
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-018-4675-4

Weitere Artikel der Ausgabe 12/2018

Journal of General Internal Medicine 12/2018 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.