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Erschienen in: Indian Journal of Thoracic and Cardiovascular Surgery 1/2019

09.10.2018 | Original Article

‘CLAS’ score: an objective tool to standardize and predict mitral valve repairability

verfasst von: Amber Malhotra, Sumbul Siddiqui, Vivek Wadhawa, Himani Pandya, Kartik Patel, Komal Shah, Hemang Gandhi, Pankaj Garg, Sudhir Adalti, Kamal Sharma

Erschienen in: Indian Journal of Thoracic and Cardiovascular Surgery | Ausgabe 1/2019

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Abstract

Purpose

Carpentier’s classification has been used to classify both stenotic and regurgitant lesions. However, given the extreme variability of lesions, a universal nomenclature suggestive of the complexity and the prognosis of the repair procedure for the entire spectrum of the mitral valve disease still remains elusive. We present the predictors of mitral valve repairability with the help of a four-level-based ‘CLAS’ scoring system.

Methods

A total of 394 patients undergoing mitral valve procedure were prospectively studied. The valvular apparatus was divided into four sub-units, namely Commissures (C), Leaflet (L), Annulus (A), and Subvalvular apparatus (S), and the components were scored individually and the summation scores were calculated. Based on our results, three CLAS groups were formulated.

Results

A total of 376 (n = 394) patients underwent successful MVRep (95.43%; on-table failure in 18 patients). A total of 276 were rheumatic, 51 degenerative, 28 congenital, and 16 had infective endocarditis. Thirty-day mortality was 14 (3.72%) while delayed re-intervention rate was 8 (2.12%). The mean follow-up period was 30 months. One hundred percent patients with a CLAS score ≤ 8 had a successful repair as compared to 93.33 and 69.69%, respectively, for patients with scores between 9 and 12 and > 12, respectively. The cardio pulmonary bypass time, aortic-cross-clamp time, and ICU stay also showed a significant correlation with the patient’s ‘CLAS’ groups.

Conclusion

The CLAS score is highly predictive of a successful repair. We thus propose that, in the patients with a score of ≤ 8, repair should always be attempted irrespective of the pathology. The patients expected to be scored > 8 should be referred to a repair reference center.
Literatur
1.
Zurück zum Zitat Rothenbühler M, O'Sullivan CJ, Stortecky S, et al. Active surveillance for rheumatic heart disease in endemic regions: a systematic review and meta-analysis of prevalence among children and adolescents. Lancet Glob Health. 2014;2:e717–26.CrossRefPubMed Rothenbühler M, O'Sullivan CJ, Stortecky S, et al. Active surveillance for rheumatic heart disease in endemic regions: a systematic review and meta-analysis of prevalence among children and adolescents. Lancet Glob Health. 2014;2:e717–26.CrossRefPubMed
2.
Zurück zum Zitat Choudhary SK, Talwar S, Dubey B, Chopra A, Saxena A, Kumar AS. Mitral valve repair in a predominantly rheumatic population: long-term results. Tex Heart Inst J. 2001;28:8–15.PubMedPubMedCentral Choudhary SK, Talwar S, Dubey B, Chopra A, Saxena A, Kumar AS. Mitral valve repair in a predominantly rheumatic population: long-term results. Tex Heart Inst J. 2001;28:8–15.PubMedPubMedCentral
3.
Zurück zum Zitat Carpentier A. Cardiac valve surgery—the “French correction”. J Thorac Cardiovasc Surg. 1983;86:323–37. Carpentier A. Cardiac valve surgery—the “French correction”. J Thorac Cardiovasc Surg. 1983;86:323–37.
4.
Zurück zum Zitat Wheeler R, Steeds R, Rana B, et al. A minimum dataset for a standard transoesophageal echocardiogram: a guideline protocol from the British Society of Echocardiography. Echo Res Pract. 2015;2:G29–45.CrossRefPubMedPubMedCentral Wheeler R, Steeds R, Rana B, et al. A minimum dataset for a standard transoesophageal echocardiogram: a guideline protocol from the British Society of Echocardiography. Echo Res Pract. 2015;2:G29–45.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Guiraudon GM, Ofiesh JG, Kaushik R. Extended vertical transatrial septal approach to the mitral valve. Ann Thorac Surg. 1991;52:1058–62.CrossRefPubMed Guiraudon GM, Ofiesh JG, Kaushik R. Extended vertical transatrial septal approach to the mitral valve. Ann Thorac Surg. 1991;52:1058–62.CrossRefPubMed
6.
Zurück zum Zitat Sampath Kumar A, Talwar S, Saxena A, Singh R, Velayoudam D. Results of mitral valve repair in rheumatic mitral regurgitation. Interact Cardiovasc Thorac Surg. 2006;5:356–61.CrossRef Sampath Kumar A, Talwar S, Saxena A, Singh R, Velayoudam D. Results of mitral valve repair in rheumatic mitral regurgitation. Interact Cardiovasc Thorac Surg. 2006;5:356–61.CrossRef
7.
Zurück zum Zitat Pomerantzeff PM, Brandão CM, Leite Filho OA, et al. Mitral valve repair in rheumatic patients with mitral insuficiency: twenty years of techniques and results. Rev Bras Cir Cardiovasc. 2009;24:485–9.CrossRefPubMed Pomerantzeff PM, Brandão CM, Leite Filho OA, et al. Mitral valve repair in rheumatic patients with mitral insuficiency: twenty years of techniques and results. Rev Bras Cir Cardiovasc. 2009;24:485–9.CrossRefPubMed
8.
Zurück zum Zitat Castillo JG, Anyanwu AC, Fuster V. Adams DH. A near 100% repair rate for mitral valve prolapse is achievable in a reference center: implications for future guidelines. J Thorac Cardiovasc Surg. 2012;144:308–12.CrossRef Castillo JG, Anyanwu AC, Fuster V. Adams DH. A near 100% repair rate for mitral valve prolapse is achievable in a reference center: implications for future guidelines. J Thorac Cardiovasc Surg. 2012;144:308–12.CrossRef
9.
Zurück zum Zitat Chauvaud S, Fuzellier JF, Berrebi A, Deloche A, Fabiani JN, Carpentier A. Long-term (29 years) results of reconstructive surgery in rheumatic mitral valve insufficiency. Circulation. 2001;104:112–5.CrossRef Chauvaud S, Fuzellier JF, Berrebi A, Deloche A, Fabiani JN, Carpentier A. Long-term (29 years) results of reconstructive surgery in rheumatic mitral valve insufficiency. Circulation. 2001;104:112–5.CrossRef
10.
Zurück zum Zitat Dillon J, Yakub MA, Kong PK, Ramli MF, Jaffar N, Gaffar IF. Comparative long-term results of mitral valve repair in adults with chronic rheumatic disease and degenerative disease: Is repair for “burnt-out” rheumatic disease still inferior to repair for degenerative disease in the current era? J Thorac Cardiovasc Surg. 2015;149:771–9. Dillon J, Yakub MA, Kong PK, Ramli MF, Jaffar N, Gaffar IF. Comparative long-term results of mitral valve repair in adults with chronic rheumatic disease and degenerative disease: Is repair for “burnt-out” rheumatic disease still inferior to repair for degenerative disease in the current era? J Thorac Cardiovasc Surg. 2015;149:771–9.
11.
Zurück zum Zitat Acar C, de Ibarra JS, Lansac E. Anterior leaflet augmentation with autologous pericardium for mitral repair in rheumatic valve insufficiency. J Heart Valve Dis. 2004;13:741–6.PubMed Acar C, de Ibarra JS, Lansac E. Anterior leaflet augmentation with autologous pericardium for mitral repair in rheumatic valve insufficiency. J Heart Valve Dis. 2004;13:741–6.PubMed
12.
Zurück zum Zitat Chotivatanapong T, Lerdsomboon P, Sungkahapong V. Rheumatic mitral valve repair: experience of 221 cases from Central Chest Institute of Thailand. J Med Assoc Thai. 2012;95:S51–7.PubMed Chotivatanapong T, Lerdsomboon P, Sungkahapong V. Rheumatic mitral valve repair: experience of 221 cases from Central Chest Institute of Thailand. J Med Assoc Thai. 2012;95:S51–7.PubMed
13.
Zurück zum Zitat Adams DH, Anyanwu AC, Rahmanian PB, Abascal V, Salzberg SP, Filsoufi F. Large annuloplasty rings facilitate mitral valve repair in Barlow’s disease. Ann Thorac Surg. 2006;82:2096–100.CrossRefPubMed Adams DH, Anyanwu AC, Rahmanian PB, Abascal V, Salzberg SP, Filsoufi F. Large annuloplasty rings facilitate mitral valve repair in Barlow’s disease. Ann Thorac Surg. 2006;82:2096–100.CrossRefPubMed
14.
Zurück zum Zitat David TE, Armstrong S, Ivanov J. Chordal replacement with polytetrafluoroethylene sutures for mitral valve repair: a 25-year experience. J Thorac Cardiovasc Surg. 2013;145:1563–9.CrossRefPubMed David TE, Armstrong S, Ivanov J. Chordal replacement with polytetrafluoroethylene sutures for mitral valve repair: a 25-year experience. J Thorac Cardiovasc Surg. 2013;145:1563–9.CrossRefPubMed
16.
Zurück zum Zitat Calafiore AM, Scandura S, Iacò AL, et al. A simple method to obtain the correct length of the artificial chordae in complex chordal replacement. J Card Surg. 2008;23:204–6.CrossRefPubMed Calafiore AM, Scandura S, Iacò AL, et al. A simple method to obtain the correct length of the artificial chordae in complex chordal replacement. J Card Surg. 2008;23:204–6.CrossRefPubMed
Metadaten
Titel
‘CLAS’ score: an objective tool to standardize and predict mitral valve repairability
verfasst von
Amber Malhotra
Sumbul Siddiqui
Vivek Wadhawa
Himani Pandya
Kartik Patel
Komal Shah
Hemang Gandhi
Pankaj Garg
Sudhir Adalti
Kamal Sharma
Publikationsdatum
09.10.2018
Verlag
Springer Singapore
Erschienen in
Indian Journal of Thoracic and Cardiovascular Surgery / Ausgabe 1/2019
Print ISSN: 0970-9134
Elektronische ISSN: 0973-7723
DOI
https://doi.org/10.1007/s12055-018-0721-4

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