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Erschienen in: Forensic Science, Medicine and Pathology 2/2019

07.08.2018 | Lessons from the Museum

Classical syphilitic lesions from the museum

verfasst von: Roger W. Byard

Erschienen in: Forensic Science, Medicine and Pathology | Ausgabe 2/2019

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Abstract

Syphilis is an increasingly diagnosed venereal disease which has four distinctive stages that may last over decades if appropriate treatment is not given. Review of the files of the Pathology Museum in the Faculty of Medicine at The University of Adelaide revealed three cases with classical cardiovascular and neurological findings. Case 1: An 80-year-old man with a large syphilitic aneurysm of the ascending aorta with a smaller aneurysm of the proximal descending aorta. Case 2: A 56-year-old man with chronic syphilitic meningoencephalitis with cerebral atrophy. Case 3: A 77-year-old man with tabes dorsalis. Given the increase in cases coming to medical attention in recent years due to high-risk sexual activity, migration, travel and reduced access to medical treatment, an awareness of the classical features of syphilis is appropriate as some cases will undoubtedly require medicolegal evaluation.
Literatur
4.
Zurück zum Zitat Hook EW. Syphilis. In: Goldman L, Schafer AI, editors. Goldman’s Cecil medicine. 24th ed. Toronto: Elsevier; 2011. p. 1922–9. Hook EW. Syphilis. In: Goldman L, Schafer AI, editors. Goldman’s Cecil medicine. 24th ed. Toronto: Elsevier; 2011. p. 1922–9.
5.
Zurück zum Zitat Byard RW. Syphilis – cardiovascular manifestations of the great imitator. J Forensic Sci. 2018;64:1312–5.CrossRef Byard RW. Syphilis – cardiovascular manifestations of the great imitator. J Forensic Sci. 2018;64:1312–5.CrossRef
9.
Zurück zum Zitat La Fond RE, Lukehart SA. Biological basis for syphilis. Clin Microbiol Rev. 2006;19:29–49.CrossRef La Fond RE, Lukehart SA. Biological basis for syphilis. Clin Microbiol Rev. 2006;19:29–49.CrossRef
10.
Zurück zum Zitat Tsokos M. Syphilitic aortic aneurysm rupture as cause of sudden death. Forensic Sci Med Pathol. 2012;8:325–6.CrossRefPubMed Tsokos M. Syphilitic aortic aneurysm rupture as cause of sudden death. Forensic Sci Med Pathol. 2012;8:325–6.CrossRefPubMed
11.
Zurück zum Zitat Roberts WC, Barbin CM, Weissenborn MR, Ko JM, Henry AC. Syphilis as a cause of thoracic aortic aneurysm. Am J Cardiol. 2015;116:1298–303.CrossRefPubMed Roberts WC, Barbin CM, Weissenborn MR, Ko JM, Henry AC. Syphilis as a cause of thoracic aortic aneurysm. Am J Cardiol. 2015;116:1298–303.CrossRefPubMed
12.
Zurück zum Zitat Roberts WC, Ko JM, Vowels TJ. Natural history of syphilitic aortitis. Am J Cardiol. 2009;104:1578–87.CrossRefPubMed Roberts WC, Ko JM, Vowels TJ. Natural history of syphilitic aortitis. Am J Cardiol. 2009;104:1578–87.CrossRefPubMed
13.
14.
15.
Zurück zum Zitat Stern R. A study of the histopathology of tabes dorsalis with special reference to Richter’s theory of its pathogenesis. Brain. 1929;52:295–316.CrossRef Stern R. A study of the histopathology of tabes dorsalis with special reference to Richter’s theory of its pathogenesis. Brain. 1929;52:295–316.CrossRef
16.
Zurück zum Zitat Brown E, Gray F. Bacterial infections. In: Love S, Louis D, Ellison DW, editors. Greenfield’s Neuropathology. 8th ed. Boca Raton: CRC Press; 2008. p. 1431. Brown E, Gray F. Bacterial infections. In: Love S, Louis D, Ellison DW, editors. Greenfield’s Neuropathology. 8th ed. Boca Raton: CRC Press; 2008. p. 1431.
17.
Zurück zum Zitat Park KH, Lee MS, Hong IK, et al. Bone involvement in secondary syphilis: a case report and systematic review of the literature. Sex Transm Dis. 2014;41:532–7.CrossRefPubMed Park KH, Lee MS, Hong IK, et al. Bone involvement in secondary syphilis: a case report and systematic review of the literature. Sex Transm Dis. 2014;41:532–7.CrossRefPubMed
19.
Zurück zum Zitat Son C, Samples D, Brenner A, Floyd J. Osteolytic calvarial lesions as initial presentation of latent neurosyphilis. J Clin Neurosci. 2010;22:909–10.CrossRef Son C, Samples D, Brenner A, Floyd J. Osteolytic calvarial lesions as initial presentation of latent neurosyphilis. J Clin Neurosci. 2010;22:909–10.CrossRef
20.
Zurück zum Zitat Newman L, Kamb M, Hawkes S, Gomez G, Say L, Seuc A, et al. Global estimates of syphilis in pregnancy and associated adverse outcomes: analysis of multinational antenatal surveillance data. PLoS Med. 2013;10:e1001396.CrossRefPubMedPubMedCentral Newman L, Kamb M, Hawkes S, Gomez G, Say L, Seuc A, et al. Global estimates of syphilis in pregnancy and associated adverse outcomes: analysis of multinational antenatal surveillance data. PLoS Med. 2013;10:e1001396.CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Nyatsanza F, Tipple C. Syphilis: presentations in general medicine. Clin Med. 2016;16:184–8.CrossRef Nyatsanza F, Tipple C. Syphilis: presentations in general medicine. Clin Med. 2016;16:184–8.CrossRef
22.
Zurück zum Zitat Forrest CE, Ward A. Clinical diagnosis of syphilis: a ten-year retrospective analysis in a south Australian urban sexual health clinic. Int J STD AIDS. 2016;27:1334–7.CrossRefPubMed Forrest CE, Ward A. Clinical diagnosis of syphilis: a ten-year retrospective analysis in a south Australian urban sexual health clinic. Int J STD AIDS. 2016;27:1334–7.CrossRefPubMed
Metadaten
Titel
Classical syphilitic lesions from the museum
verfasst von
Roger W. Byard
Publikationsdatum
07.08.2018
Verlag
Springer US
Erschienen in
Forensic Science, Medicine and Pathology / Ausgabe 2/2019
Print ISSN: 1547-769X
Elektronische ISSN: 1556-2891
DOI
https://doi.org/10.1007/s12024-018-0012-9

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