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Infection

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06.09.2018 | Brief Report

Clinical and microbiological characteristics of adult invasive Haemophilus influenzae infections: results of a 14-year single-center experience from Hungary

verfasst von: Balint Gergely Szabo, Katalin Szidonia Lenart, Tamas Tirczka, Eszter Ostorhazi

Erschienen in: Infection | Ausgabe 6/2018

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Abstract

To describe the characteristics of adult invasive H. influenzae disease, 34 patients diagnosed at a single tertiary center between 2004 and 2017 were analyzed in a retrospective case series study. The annual estimated incidence was 0.1 cases/100.000 inhabitants. Dominant source of infection was pneumonia accompanied by sepsis (62%) and caused by nontypeable strains (74%) with low ampicillin resistance (14%). Survival (94%) and complication rates were high (35%). Main empirical treatments were ceftriaxone or levofloxacine.

Ieven M, Coenen S, Loens K, Lammens C, Coenjaerts F, Vanderstraeten A, et al. Aetiology of lower respiratory tract infection in adults in primary care: a prospective study in 11 European countries. Clin Microbiol Infect. 2018;2–7. https://doi.org/10.1016/j.cmi.2018.02.004 CrossRef

Shimol SB, Dagan R. Haemophilus influenzae: still a relevant invasive pathogen. Isr Med Assoc J. 2012;14:432–4.PubMed

Falla T, Crook D, Brophy L, Maskell D, Kroll J, Moxon E. PCR for capsular typing of Haemophilus influenzae. J Clin Microbiol. 1994;32:2382–6.PubMedPubMedCentral

National Bacteriological Surveillance Management Team. NBS Annual Reports, 2005–2016 [Internet]. National Center for Epidemiology (Budapest, Hungary). 2017. Available from: http://www.oek.hu/oek.web?to=2479&nid=505&pid=1&lang=hun. Accessed 15 Jan 2018.

Ladhani S, Slack MP, Heath PT, Von Gottberg A, Chandra M, Ramsay ME, et al. Invasive Haemophilus influenzae disease, Europe, 1996–2006. Emerg Infect Dis. 2010;16:455–63.CrossRef

Whittaker R, Economopoulou A, Dias JG, Bancroft E, Ramliden M, Celentano LP. Epidemiology of invasive Haemophilus influenzae disease, Europe, 2007–2014. Emerg Infect Dis. 2017;23:396–404.CrossRef

MacNeil JR, Cohn AC, Farley M, Mair R, Baumbach J, Bennett N, et al. Current epidemiology and trends in invasive Haemophilus influenzae disease—United States, 1989–2008. Clin Infect Dis. 2011;53:1230–6.CrossRef

Puig C, Grau I, Marti S, Tubau F, Calatayud L, Pallares R, et al. Clinical and molecular epidemiology of Haemophilus influenzae causing invasive disease in adult patients. PLoS One. 2014;9:1–7.

Blain A, MacNeil J, Wang X, Bennett N, Farley M, Harrison LH, et al. Invasive Haemophilus influenzae disease in adults ≥ 65 years, United States, 2011. Open Forum Infect Dis. 2014;1:ofu044.CrossRef

10.

Kiliç H, Akyol S, Parkan ÕM, Dinç G, Sav H, Aydemir G. Molecular characterization and antibiotic susceptibility of Haemophilus influenzae clinical isolates. Inf Med. 2017;25:27–32.

11.

Bae S, Lee J, Lee J, Kim E, Lee S, Yu J, et al. Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. Antimicrob Agents Chemother. 2010;54:65–71.CrossRef

12.

Ministry of Human Capacities National Public Health and Medical Officer Service Department of Hospital Hygiene and Epidemiology Surveillance. Annual reports on the national epidemiological situation and outbreaks, 2001–2016 [Internet]. National Center for Epidemiology (Budapest, Hungary). 2017. http://www.oek.hu/oek.web?to=2475,2465&nid=509&pid=1&lang=hun. Accessed 15 Jan 2018.

13.

Van Wessel K, Rodenburg GD, Veenhoven RH, Spanjaard L, Van Der Ende A, Sanders EAM. Nontypeable Haemophilus influenzae invasive disease in the Netherlands: a retrospective surveillance study 2001–2008. Clin Infect Dis. 2011;53:8–12.

14.

Laupland KB, Schønheyder HC, Østergaard C, Knudsen JD, Valiquette L, Galbraith J, et al. Epidemiology of Haemophilus influenzae Bacteremia: a multi-national population-based assessment. J Infect. 2011;62:142–8.CrossRef

Titel: Clinical and microbiological characteristics of adult invasive Haemophilus influenzae infections: results of a 14-year single-center experience from Hungary
verfasst von: Balint Gergely Szabo
Katalin Szidonia Lenart
Tamas Tirczka
Eszter Ostorhazi
Publikationsdatum: 06.09.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Infection / Ausgabe 6/2018
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-018-1213-6

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Clinical and microbiological characteristics of adult invasive Haemophilus influenzae infections: results of a 14-year single-center experience from Hungary

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