Skip to main content
main-content

29.10.2019 | Clinical Investigation | Ausgabe 6/2019

Japanese Journal of Ophthalmology 6/2019

Clinical characteristics of cuticular drusen in the Japanese population

Zeitschrift:
Japanese Journal of Ophthalmology > Ausgabe 6/2019
Autoren:
Yoichi Sakurada, Koji Tanaka, Akiko Miki, Hidetaka Matsumoto, Akiyuki Kawamura, Ryo Mukai, Hideo Akiyama, Shigeru Honda, Ryusaburo Mori, Hiroyuki Iijima
Wichtige Hinweise
Corresponding author: Yoichi Sakurada

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Purpose

To investigate the clinical characteristics of eyes with cuticular drusen in Japanese individuals, while paying special attention to large colloid drusen (LCD).

Study design

Retrospective case series.

Methods

Eyes with cuticular drusen, from patients of 4 medical institutes in Japan, were investigated. Multimodal imaging findings were used to diagnose cuticular drusen. LCD was defined as cuticular drusen > 200 µm.

Results

Twenty-four eyes from 12 patients (8 women, 4 men) were diagnosed with cuticular drusen. The mean age of all patients (n = 12) was 60.8 years. The mean age of patients without additional macular pathology (n = 5) was 55.4 years. Of the 7 patients with additional macular pathology, 6 (85.7%) exhibited age-related macular degeneration-associated macular pathology, including drusenoid pigment epithelial detachment (PED) (8 eyes from 4 patients), geographic atrophy (2 eyes from 1 patient), and occult choroidal neovascularization (1 eye). LCD were found in 6 eyes of 3 patients (25%), those with LCD were on average 53.7 ± 8.7 years old and those without 69.9 ± 14.1 years of age (P = 0.064, Mann–Whitney U test).

Conclusions

Cuticular drusen were predominantly seen in females, and drusenoid PED was most frequently seen in eyes with additional macular pathology. LCD were seen in 25% of eyes with cuticular drusen.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 6/2019

Japanese Journal of Ophthalmology 6/2019 Zur Ausgabe

Scientific Reviewers

Scientific Reviewers

Neu im Fachgebiet Augenheilkunde

22.10.2019 | Erkrankungen der Lider | CME | Ausgabe 11/2019

Floppy-Eyelid-Syndrom

Ein häufig unterdiagnostiziertes Krankheitsbild mit interdisziplinärer Bedeutung

24.09.2019 | Der Ophthalmologe | CME | Ausgabe 10/2019

Konjunktivale Malignome

18.09.2019 | Leitthema | Ausgabe 10/2019

Toxizität von schweren Flüssigkeiten