The online version of this article (doi:10.1186/1471-2253-14-27) contains supplementary material, which is available to authorized users.
Taek Kyu Park, Jeong Hoon Yang contributed equally to this work.
The authors declare that they have no competing interests.
All authors contributed to the study design, acquisition of data, or analysis and interpretation of data and have been involved in drafting the manuscript. JHY, S-HC, YBS, J-YH, J-HC, KS, YTL and H-CG participated in the enrolment of patients, performed the procedures, and contributed to clinical follow-up. TKP, JHY, S-HC, YBS, J-YH, J-HC, KS, YTL and H-CG participated in data collection. TKP, JHY, and S-HC participated in the data analysis. TKP, JHY, S-HC, YBS, J-YH, J-HC, KS, YTL and H-CG contributed to data interpretation. TKP, JHY and S-HC contributed to writing of the manuscript. All authors gave final approval of the manuscript for publication.
There is no available data on clinical outcome in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock who are supported by an intra-aortic balloon pump (IABP) in combination with extracorporeal life support (ECLS).
We analysed 96 consecutive patients with AMI and complicating cardiogenic shock who were assisted by an ECLS system between January 2004 and December 2011. The primary outcome was in-hospital mortality. The secondary outcomes were the success rate of weaning from ECLS and the lactate clearance for 48 hours (%).
A combination of IABP and ECLS was used in 41 (42.7%) patients. In-hospital mortality occurred for 51 patients (ECLS with IABP versus ECLS alone; 51.2% vs. 54.5%, p = 0.747). The success rate of weaning from ECLS was similar between the two groups (63.4% vs. 58.2%, p = 0.604). Complications such as ischemia of a lower extremity or bleeding at the ECLS insertion site (p = 0.521 and p = 0.667, respectively) did not increase when ECLS was combined with IABP. Among patients who survived for 24 hours after intervention, lactate clearance was not significantly different between patients who received ECLS alone and those who received ECLS with IABP (p = 0.918).
The combined use of ECLS and IABP did not improve in-hospital survival in patients with AMI complicated by cardiogenic shock.
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- Clinical impact of intra-aortic balloon pump during extracorporeal life support in patients with acute myocardial infarction complicated by cardiogenic shock
Taek Kyu Park
Jeong Hoon Yang
Young Bin Song
Young Tak Lee
- BioMed Central
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